Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice P Sonveaux, F Végran, T Schroeder, MC Wergin, J Verrax, ZN Rabbani, ... The Journal of clinical investigation 118 (12), 3930-3942, 2008 | 1881 | 2008 |
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis P Sonveaux, T Copetti, CJ De Saedeleer, F Vegran, J Verrax, ... PloS one 7 (3), e33418, 2012 | 562 | 2012 |
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver LB Bindels, P Porporato, EM Dewulf, J Verrax, AM Neyrinck, JC Martin, ... British journal of cancer 107 (8), 1337-1344, 2012 | 299 | 2012 |
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects J Verrax, PB Calderon Free Radical Biology and Medicine 47 (1), 32-40, 2009 | 288 | 2009 |
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells CJ De Saedeleer, T Copetti, PE Porporato, J Verrax, O Feron, ... Public Library of Science 7 (10), e46571, 2012 | 280 | 2012 |
Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model LB Bindels, R Beck, O Schakman, JC Martin, F De Backer, FM Sohet, ... PloS one 7 (6), e37971, 2012 | 271 | 2012 |
Regulation of catalase expression in healthy and cancerous cells C Glorieux, M Zamocky, JM Sandoval, J Verrax, PB Calderon Free Radical Biology and Medicine 87, 84-97, 2015 | 270 | 2015 |
Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy C Glorieux, N Dejeans, B Sid, R Beck, PB Calderon, J Verrax Biochemical pharmacology 82 (10), 1384-1390, 2011 | 185 | 2011 |
Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease B Sid, J Verrax, PB Calderon Biochemical pharmacology 86 (2), 200-209, 2013 | 148 | 2013 |
Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents J Benites, JA Valderrama, K Bettega, RC Pedrosa, PB Calderon, J Verrax European journal of medicinal chemistry 45 (12), 6052-6057, 2010 | 134 | 2010 |
The controversial place of vitamin C in cancer treatment J Verrax, PB Calderon biochemical pharmacology 76 (12), 1644-1652, 2008 | 133 | 2008 |
Arsenic trioxide treatment decreases the oxygen consumption rate of tumor cells and radiosensitizes solid tumors C Diepart, O Karroum, J Magat, O Feron, J Verrax, PB Calderon, ... Cancer research 72 (2), 482-490, 2012 | 130 | 2012 |
Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death J Verrax, J Cadrobbi, C Marques, H Taper, Y Habraken, J Piette, ... Apoptosis 9, 223-233, 2004 | 130 | 2004 |
Comparison of methods for measuring oxygen consumption in tumor cells in vitro C Diepart, J Verrax, PB Calderon, O Feron, BF Jordan, B Gallez Analytical biochemistry 396 (2), 250-256, 2010 | 129 | 2010 |
Role of oxidative stress in the pathogenesis of alcohol-induced liver disease B Sid, J Verrax, PB Calderon Free radical research 47 (11), 894-904, 2013 | 117 | 2013 |
Overexpression of GRP94 in breast cancer cells resistant to oxidative stress promotes high levels of cancer cell proliferation and migration: implications for tumor recurrence N Dejeans, C Glorieux, S Guenin, R Beck, B Sid, R Rousseau, B Bisig, ... Free Radical Biology and Medicine 52 (6), 993-1002, 2012 | 112 | 2012 |
Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study J Verrax, M Delvaux, N Beghein, H Taper, B Gallez, P Buc Calderon Free radical research 39 (6), 649-657, 2005 | 112 | 2005 |
The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy J Verrax, J Cadrobbi, M Delvaux, JM Jamison, J Gilloteaux, JL Summers, ... European journal of medicinal chemistry 38 (5), 451-457, 2003 | 108 | 2003 |
Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice J Verrax, J Stockis, A Tison, HS Taper, PB Calderon Biochemical pharmacology 72 (6), 671-680, 2006 | 102 | 2006 |
Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death R Beck, J Verrax, T Gonze, M Zappone, RC Pedrosa, H Taper, O Feron, ... Biochemical pharmacology 77 (3), 375-383, 2009 | 90 | 2009 |