DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts D Roulois, HL Yau, R Singhania, Y Wang, A Danesh, SY Shen, H Han, ... Cell 162 (5), 961-973, 2015 | 1263 | 2015 |
Sensitive tumour detection and classification using plasma cell-free DNA methylomes SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ... Nature 563 (7732), 579-583, 2018 | 703 | 2018 |
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ... Nature medicine 26 (7), 1041-1043, 2020 | 212 | 2020 |
Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes F Nassiri, A Chakravarthy, S Feng, SY Shen, R Nejad, JA Zuccato, ... Nature medicine 26 (7), 1044-1047, 2020 | 210 | 2020 |
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2 S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ... Cancer cell 30 (2), 337-348, 2016 | 207 | 2016 |
Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA SY Shen, JM Burgener, SV Bratman, DD De Carvalho Nature protocols 14 (10), 2749-2780, 2019 | 137 | 2019 |
Seasonal variation of bacterial endophytes in urban trees SY Shen, R Fulthorpe Frontiers in microbiology 6, 127068, 2015 | 94 | 2015 |
Bacterial endophytes isolated from plants in natural oil seep soils with chronic hydrocarbon contamination R Lumactud, SY Shen, M Lau, R Fulthorpe Frontiers in microbiology 7, 185762, 2016 | 74 | 2016 |
Tumor-naïve multimodal profiling of circulating tumor DNA in head and neck squamous cell carcinoma JM Burgener, J Zou, Z Zhao, Y Zheng, SY Shen, SH Huang, S Keshavarzi, ... Clinical Cancer Research 27 (15), 4230-4244, 2021 | 63 | 2021 |
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells HL Yau, E Bell, I Ettayebi, FC de Almeida, GM Boukhaled, SY Shen, ... Molecular cell 81 (7), 1469-1483. e8, 2021 | 62 | 2021 |
An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors K Taylor, HL Yau, A Chakravarthy, B Wang, SY Shen, I Ettayebi, CA Ishak, ... Journal for immunotherapy of cancer 8 (2), 2020 | 44 | 2020 |
The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors S Chen, J Petricca, W Ye, J Guan, Y Zeng, N Cheng, L Gong, SY Shen, ... Nature communications 13 (1), 6467, 2022 | 30 | 2022 |
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet C Viner, CA Ishak, J Johnson, NJ Walker, H Shi, MK Sjöberg-Herrera, ... Genome biology 25 (1), 11, 2024 | 27 | 2024 |
Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment MR Peter, M Bilenky, R Isserlin, GD Bader, SY Shen, DD De Carvalho, ... Epigenomics 12 (15), 1317-1332, 2020 | 16 | 2020 |
Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification JA Zuccato, V Patil, S Mansouri, M Voisin, A Chakravarthy, SY Shen, ... Neuro-oncology 25 (8), 1452-1460, 2023 | 14 | 2023 |
Seasonal variation of bacterial endophytes in urban trees. Front Microbiol 6: 427 SY Shen, R Fulthorpe | 12 | 2015 |
PacBio SMRT assembly of a complex multi-replicon genome reveals chlorocatechol degradative operon in a region of genome plasticity N Ricker, SY Shen, J Goordial, S Jin, RR Fulthorpe Gene 586 (2), 239-247, 2016 | 11 | 2016 |
Fungal endophytes increase biomass production in pale swallow-wort (Vincetoxicum rossicum (Kleopow) Barbar.) RB Dickinson, RS Bourchier, RR Fulthorpe, SY Shen, IM Jones, SM Smith Botany 99 (6), 337-353, 2021 | 6 | 2021 |
Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls SL Wilson, SY Shen, L Harmon, JM Burgener, T Triche, SV Bratman, ... Cell Reports Methods 2 (9), 2022 | 3 | 2022 |
Methods of capturing cell-free methylated dna and uses of same DD De Carvalho, SY Shen, R Singhania | 3 | 2017 |