| Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ... Nature medicine 25 (1), 165-175, 2019 | 681 | 2019 |
| Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease ST Ferreira, JR Clarke, TR Bomfim, FG De Felice Alzheimer's & dementia 10 (1), S76-S83, 2014 | 417 | 2014 |
| TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013 | 392 | 2013 |
| Plastic modifications induced by object recognition memory processing JR Clarke, M Cammarota, A Gruart, I Izquierdo, JM Delgado-García Proceedings of the National Academy of Sciences 107 (6), 2652-2657, 2010 | 323 | 2010 |
| The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease AF Batista, L Forny‐Germano, JR Clarke, NM Lyra e Silva, J Brito‐Moreira, ... The Journal of pathology 245 (1), 85-100, 2018 | 203 | 2018 |
| Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers CP Figueiredo, JR Clarke, JH Ledo, FC Ribeiro, CV Costa, HM Melo, ... Journal of Neuroscience 33 (23), 9626-9634, 2013 | 203 | 2013 |
| Alzheimer‐associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation JR Clarke, NM Lyra e Silva, CP Figueiredo, RL Frozza, JH Ledo, ... EMBO molecular medicine 7 (2), 190-210, 2015 | 199 | 2015 |
| Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice JH Ledo, EP Azevedo, JR Clarke, FC Ribeiro, CP Figueiredo, D Foguel, ... Molecular psychiatry 18 (10), 1053-1054, 2013 | 162 | 2013 |
| Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice CP Figueiredo, FGQ Barros-Aragão, RLS Neris, PS Frost, C Soares, ... Nature communications 10 (1), 3890, 2019 | 147 | 2019 |
| Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease NM Lyra e Silva, RA Gonçalves, TA Pascoal, RAS Lima-Filho, ... Translational psychiatry 11 (1), 251, 2021 | 134 | 2021 |
| Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs object recognition long-term memory JR Clarke, JI Rossato, S Monteiro, LRM Bevilaqua, I Izquierdo, ... Neurobiology of learning and memory 90 (2), 374-381, 2008 | 107 | 2008 |
| Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice GC Kincheski, IS Valentim, JR Clarke, D Cozachenco, ... Brain, behavior, and immunity 64, 140-151, 2017 | 102 | 2017 |
| Acute and chronic neurological consequences of early-life Zika virus infection in mice I Nem de Oliveira Souza, PS Frost, JV França, JB Nascimento-Viana, ... Science translational medicine 10 (444), eaar2749, 2018 | 91 | 2018 |
| Palmitate is increased in the cerebrospinal fluid of humans with obesity and induces memory impairment in mice via pro-inflammatory TNF-α HM Melo, GSS da Silva, MR Sant’Ana, CVL Teixeira, JR Clarke, ... Cell Reports 30 (7), 2180-2194. e8, 2020 | 89 | 2020 |
| Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice J Brito-Moreira, MV Lourenco, MM Oliveira, FC Ribeiro, JH Ledo, LP Diniz, ... Journal of Biological Chemistry 292 (18), 7327-7337, 2017 | 87 | 2017 |
| Metabolic dysfunction in Alzheimer’s disease: from basic neurobiology to clinical approaches JR Clarke, FC Ribeiro, RL Frozza, FG De Felice, MV Lourenco Journal of Alzheimer's Disease 64 (s1), S405-S426, 2018 | 81 | 2018 |
| SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice FL Fontes-Dantas, GG Fernandes, EG Gutman, EV De Lima, LS Antonio, ... Cell reports 42 (3), 2023 | 47 | 2023 |
| Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson’s disease-like symptoms in mice JTS Fortuna, M Gralle, D Beckman, FS Neves, LP Diniz, PS Frost, ... Behavioural brain research 333, 150-160, 2017 | 42 | 2017 |
| The socio-economics of forest and woodland resource use: a hidden economy J Clarke, IM Grundy Indigenous forests and woodlands in South Africa. policy, people and …, 2004 | 35 | 2004 |
| Brain-defective insulin signaling is associated to late cognitive impairment in post-septic mice FS Neves, PT Marques, F Barros‑Aragão, JB Nunes, AM Venancio, ... Molecular Neurobiology 55, 435-444, 2018 | 34 | 2018 |
