|Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models|
MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ...
Nature medicine 25 (1), 165-175, 2019
|Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease|
ST Ferreira, JR Clarke, TR Bomfim, FG De Felice
Alzheimer's & dementia 10 (1), S76-S83, 2014
|TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys|
MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ...
Cell metabolism 18 (6), 831-843, 2013
|Plastic modifications induced by object recognition memory processing|
JR Clarke, M Cammarota, A Gruart, I Izquierdo, JM Delgado-García
Proceedings of the National Academy of Sciences 107 (6), 2652-2657, 2010
|Alzheimer‐associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation|
JR Clarke, NM Lyra e Silva, CP Figueiredo, RL Frozza, JH Ledo, ...
EMBO molecular medicine 7 (2), 190-210, 2015
|Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers|
CP Figueiredo, JR Clarke, JH Ledo, FC Ribeiro, CV Costa, HM Melo, ...
Journal of Neuroscience 33 (23), 9626-9634, 2013
|The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease|
AF Batista, L Forny‐Germano, JR Clarke, NM Lyra e Silva, J Brito‐Moreira, ...
The Journal of pathology 245 (1), 85-100, 2018
|Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice|
JH Ledo, EP Azevedo, JR Clarke, FC Ribeiro, CP Figueiredo, D Foguel, ...
Molecular psychiatry 18 (10), 1053-1054, 2013
|Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs object recognition long-term memory|
JR Clarke, JI Rossato, S Monteiro, LRM Bevilaqua, I Izquierdo, ...
Neurobiology of learning and memory 90 (2), 374-381, 2008
|Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice|
CP Figueiredo, FGQ Barros-Aragão, RLS Neris, PS Frost, C Soares, ...
Nature communications 10 (1), 1-16, 2019
|Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice|
GC Kincheski, IS Valentim, JR Clarke, D Cozachenco, ...
Brain, behavior, and immunity 64, 140-151, 2017
|Acute and chronic neurological consequences of early-life Zika virus infection in mice|
I Nem de Oliveira Souza, PS Frost, JV França, JB Nascimento-Viana, ...
Science translational medicine 10 (444), eaar2749, 2018
|Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice|
J Brito-Moreira, MV Lourenco, MM Oliveira, FC Ribeiro, JH Ledo, LP Diniz, ...
Journal of Biological Chemistry 292 (18), 7327-7337, 2017
|Metabolic dysfunction in Alzheimer’s disease: from basic neurobiology to clinical approaches|
JR Clarke, FC Ribeiro, RL Frozza, FG De Felice, MV Lourenco
Journal of Alzheimer's Disease 64 (s1), S405-S426, 2018
|Palmitate is increased in the cerebrospinal fluid of humans with obesity and induces memory impairment in mice via pro-inflammatory TNF-α|
HM Melo, GSS da Silva, MR Sant’Ana, CVL Teixeira, JR Clarke, ...
Cell Reports 30 (7), 2180-2194. e8, 2020
|The socio-economics of forest and woodland resource use: a hidden economy.|
J Clarke, IM Grundy
Indigenous forests and woodlands in South Africa: policy, people and …, 2004
|Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson’s disease-like symptoms in mice|
JTS Fortuna, M Gralle, D Beckman, FS Neves, LP Diniz, PS Frost, ...
Behavioural Brain Research 333, 150-160, 2017
|Brain-defective insulin signaling is associated to late cognitive impairment in post-septic mice|
FS Neves, PT Marques, F Barros‑Aragão, JB Nunes, AM Venancio, ...
Molecular Neurobiology 55 (1), 435-444, 2018
|Late neurological consequences of zika virus infection: Risk factors and pharmaceutical approaches|
INO Souza, FGQ Barros-Aragão, PS Frost, CP Figueiredo, JR Clarke
Pharmaceuticals 12 (2), 60, 2019
|Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice|
PS Frost, F Barros-Aragão, RT da Silva, A Venancio, I Matias, ...
Cell death & disease 10 (4), 1-13, 2019