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Brendan Prideaux
Brendan Prideaux
University of Teaxs Medical Branch
E-mail confirmado em utmb.edu
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The association between sterilizing activity and drug distribution into tuberculosis lesions
B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ...
Nature medicine 21 (10), 1223-1227, 2015
4712015
Mass spectrometry imaging for drug distribution studies
B Prideaux, M Stoeckli
Journal of proteomics 75 (16), 4999-5013, 2012
3082012
Inflammatory signaling in human tuberculosis granulomas is spatially organized
MJ Marakalala, RM Raju, K Sharma, YJ Zhang, EA Eugenin, B Prideaux, ...
Nature medicine 22 (5), 531-538, 2016
2932016
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions
B Prideaux, V Dartois, D Staab, DM Weiner, A Goh, LE Via, CE Barry III, ...
Analytical chemistry 83 (6), 2112-2118, 2011
2852011
Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development
EG Solon, A Schweitzer, M Stoeckli, B Prideaux
The AAPS journal 12, 11-26, 2010
2802010
Fatty acid synthesis is required for breast cancer brain metastasis
GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ...
Nature cancer 2 (4), 414-428, 2021
1652021
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice
SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ...
ACS infectious diseases 2 (4), 251-267, 2016
1292016
Statin adjunctive therapy shortens the duration of TB treatment in mice
NK Dutta, N Bruiners, ML Pinn, MD Zimmerman, B Prideaux, V Dartois, ...
Journal of Antimicrobial Chemotherapy 71 (6), 1570-1577, 2016
1062016
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development
T Beites, K O’Brien, D Tiwari, CA Engelhart, S Walters, J Andrews, ...
Nature communications 10 (1), 4970, 2019
972019
Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific
V Guerrini, B Prideaux, L Blanc, N Bruiners, R Arrigucci, S Singh, ...
PLoS pathogens 14 (8), e1007223, 2018
912018
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives
LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ...
ACS infectious diseases 1 (5), 203-214, 2015
822015
Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model
Y Zhao, B Prideaux, Y Nagasaki, MH Lee, PY Chen, L Blanc, H Ho, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 01009-17, 2017
812017
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy
M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ...
Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017
792017
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling
B Prideaux, MS ElNaggar, M Zimmerman, JM Wiseman, X Li, V Dartois
International journal of mass spectrometry 377, 699-708, 2015
752015
Visualization of mycobacterial biomarkers and tuberculosis drugs in infected tissue by MALDI-MS imaging
L Blanc, A Lenaerts, V Dartois, B Prideaux
Analytical chemistry 90 (10), 6275-6282, 2018
722018
Tumor drug penetration measurements could be the neglected piece of the personalized cancer treatment puzzle
IH Bartelink, EF Jones, SK Shahidi‐Latham, PRE Lee, Y Zheng, P Vicini, ...
Clinical Pharmacology & Therapeutics 106 (1), 148-163, 2019
712019
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach
E Pienaar, J Sarathy, B Prideaux, J Dietzold, V Dartois, DE Kirschner, ...
PLoS computational biology 13 (8), e1005650, 2017
652017
Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer
M Holzlechner, E Eugenin, B Prideaux
Cancer reports 2 (6), e1229, 2019
552019
High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types
L Blanc, IB Daudelin, BK Podell, PY Chen, M Zimmerman, AJ Martinot, ...
Elife 7, e41115, 2018
542018
Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations
J Sarathy, L Blanc, N Alvarez-Cabrera, P O’brien, I Dias-Freedman, ...
Antimicrobial agents and chemotherapy 63 (5), 10.1128/aac. 02516-18, 2019
532019
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