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Jaydeep K. Srimani
Jaydeep K. Srimani
Takeda Pharmaceutical
E-mail confirmado em takeda.com
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Persistence and reversal of plasmid-mediated antibiotic resistance
AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer, R Durrett, L You
Nature communications 8 (1), 1689, 2017
2942017
Antibiotics as a selective driver for conjugation dynamics
AJ Lopatkin, S Huang, RP Smith, JK Srimani, TA Sysoeva, S Bewick, ...
Nature microbiology 1 (6), 1-8, 2016
2562016
Collective antibiotic tolerance: mechanisms, dynamics and intervention
HR Meredith, JK Srimani, AJ Lee, AJ Lopatkin, L You
Nature chemical biology 11 (3), 182-188, 2015
1632015
The inoculum effect and band‐pass bacterial response to periodic antibiotic treatment
C Tan, R Phillip Smith, JK Srimani, KA Riccione, S Prasada, M Kuehn, ...
Molecular systems biology 8 (1), 617, 2012
1192012
Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control
P Dong, MV Maddali, JK Srimani, F Thélot, JR Nevins, B Mathey-Prevot, ...
Nature communications 5 (1), 4750, 2014
832014
Programmed Allee effect in bacteria causes a tradeoff between population spread and survival
R Smith, C Tan, JK Srimani, A Pai, KA Riccione, H Song, L You
Proceedings of the National Academy of Sciences 111 (5), 1969-1974, 2014
762014
Activity of transgene-produced B-domain–deleted factor VIII in human plasma following AAV5 gene therapy
S Rosen, S Tiefenbacher, M Robinson, M Huang, J Srimani, D Mackenzie, ...
Blood, The Journal of the American Society of Hematology 136 (22), 2524-2534, 2020
582020
Drug detoxification dynamics explain the postantibiotic effect
JK Srimani, S Huang, AJ Lopatkin, L You
Molecular Systems Biology 13 (10), 948, 2017
352017
Dynamic control and quantification of bacterial population dynamics in droplets
S Huang, JK Srimani, AJ Lee, Y Zhang, AJ Lopatkin, KW Leong, L You
Biomaterials 61, 239-245, 2015
312015
Persistence and reversal of plasmid-mediated antibiotic resistance. Nat Commun 8: 1689
AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer, R Durrett, L You
Nature Publishing Group, 2017
192017
Antibiotics as a selective driver for conjugation dynamics. Nat Microbiol 1: 16044
AJ Lopatkin, S Huang, RP Smith, JK Srimani, TA Sysoeva, S Bewick, ...
152016
Generic metric to quantify quorum sensing activation dynamics
A Pai, JK Srimani, Y Tanouchi, L You
ACS synthetic biology 3 (4), 220-227, 2014
122014
Persistence and reversal of plasmid-mediated antibiotic resistance. Nat Commun. 2017; 8: 1689
AJ Lopatkin, HR Meredith, JK Srimani, C Pfeiffer, R Durrett, L You
PUBMED, 0
9
Population pharmacokinetic/pharmacodynamic joint modeling of ixazomib efficacy and safety using data from the pivotal phase III TOURMALINE‐MM1 study in multiple myeloma patients
JK Srimani, PM Diderichsen, MJ Hanley, K Venkatakrishnan, R Labotka, ...
CPT: Pharmacometrics & Systems Pharmacology 11 (8), 1085-1099, 2022
42022
Linear population allocation by bistable switches in response to transient stimulation
JK Srimani, G Yao, J Neu, Y Tanouchi, TJ Lee, L You
PLoS One 9 (8), e105408, 2014
42014
Lack of germline transmission in male mice following a single intravenous administration of AAV5-hFVIII-SQ gene therapy
C Fonck, C Su, J Arens, E Koziol, J Srimani, J Henshaw, A Van Tuyl, ...
Gene Therapy 30 (7), 581-586, 2023
32023
Young mice administered adult doses of AAV5-hFVIII-SQ achieve therapeutic factor VIII expression into adulthood
L Zhang, B Yates, R Murphy, S Liu, L Xie, B Handyside, CR Sihn, ...
Molecular Therapy-Methods & Clinical Development 26, 519-531, 2022
32022
Emergent dynamics from quorum eavesdropping
JK Srimani, L You
Chemistry & biology 21 (12), 1601-1602, 2014
32014
Dose Titration of Ixazomib Maintenance Therapy in Transplant‐Ineligible Multiple Myeloma: Exposure–Response Analysis of the TOURMALINE‐MM4 Study
JK Srimani, PM Diderichsen, MJ Hanley, R Labotka, N Gupta
Clinical Pharmacology & Therapeutics 114 (1), 220-229, 2023
22023
A distributed system for fast alignment of next-generation sequencing data
JK Srimani, PY Wu, JH Phan, MD Wang
2010 IEEE International Conference on Bioinformatics and Biomedicine …, 2010
22010
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Artigos 1–20