Philip Hawkins
Philip Hawkins
Professor of Medicine
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NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
L Agostini, F Martinon, K Burns, MF McDermott, PN Hawkins, J Tschopp
Immunity 20 (3), 319-325, 2004
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International …
MA Gertz, R Comenzo, RH Falk, JP Fermand, BP Hazenberg, ...
American journal of hematology 79 (4), 319-328, 2005
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
DR Booth, M Sunde, V Bellotti, CV Robinson, WL Hutchinson, PE Fraser, ...
Nature 385 (6619), 787-793, 1997
Cardiovascular magnetic resonance in cardiac amyloidosis
AM Maceira, J Joshi, SK Prasad, JC Moon, E Perugini, I Harding, ...
Circulation 111 (2), 186-193, 2005
Patisiran, an RNAi therapeutic, for hereditary transthyretin amyloidosis
D Adams, A Gonzalez-Duarte, WD O’Riordan, CC Yang, M Ueda, ...
New England Journal of Medicine 379 (1), 11-21, 2018
Natural history and outcome in systemic AA amyloidosis
HJ Lachmann, HJB Goodman, JA Gilbertson, JR Gallimore, CA Sabin, ...
New England Journal of Medicine 356 (23), 2361-2371, 2007
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
R Goldbach-Mansky, NJ Dailey, SW Canna, A Gelabert, J Jones, BI Rubin, ...
New England Journal of Medicine 355 (6), 581-592, 2006
Use of canakinumab in the cryopyrin-associated periodic syndrome
HJ Lachmann, I Kone-Paut, JB Kuemmerle-Deschner, KS Leslie, ...
New England Journal of Medicine 360 (23), 2416-2425, 2009
Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease.
DM Vigushin, MB Pepys, PN Hawkins
The Journal of clinical investigation 91 (4), 1351-1357, 1993
Targeting C-reactive protein for the treatment of cardiovascular disease
MB Pepys, GM Hirschfield, GA Tennent, JR Gallimore, MC Kahan, ...
Nature 440 (7088), 1217-1221, 2006
Safety and efficacy of RNAi therapy for transthyretin amyloidosis
T Coelho, D Adams, A Silva, P Lozeron, PN Hawkins, T Mant, J Perez, ...
New England Journal of Medicine 369 (9), 819-829, 2013
Nonbiopsy diagnosis of cardiac transthyretin amyloidosis
JD Gillmore, MS Maurer, RH Falk, G Merlini, T Damy, A Dispenzieri, ...
Circulation 133 (24), 2404-2412, 2016
Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis
HJ Lachmann, DR Booth, SE Booth, A Bybee, JA Gilbertson, JD Gillmore, ...
New England Journal of Medicine 346 (23), 1786-1791, 2002
Human lysozyme gene mutations cause hereditary systemic amyloidosis
MB Pepys, PN Hawkins, DR Booth, DM Vigushin, GA Tennent, AK Soutar, ...
Nature 362 (6420), 553-557, 1993
Spectrum of clinical features in Muckle‐Wells syndrome and response to anakinra
PN Hawkins, HJ Lachmann, E Aganna, MF McDermott
Arthritis & Rheumatism: Official Journal of the American College of …, 2004
New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes
G Palladini, A Dispenzieri, MA Gertz, S Kumar, A Wechalekar, ...
Journal of clinical oncology 30 (36), 4541-4549, 2012
Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein
JD Gillmore, LB Lovat, MR Persey, MB Pepys, PN Hawkins
The Lancet 358 (9275), 24-29, 2001
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
MB Pepys, J Herbert, WL Hutchinson, GA Tennent, HJ Lachmann, ...
Nature 417 (6886), 254-259, 2002
Clinical improvement and amyloid regression after liver transplantation in hereditary transthyretin amyloidosis
G Holmgren, L Steen, O Suhr, BG Ericzon, CG Groth, O Andersen, ...
The Lancet 341 (8853), 1113-1116, 1993
Evaluation of Systemic Amyloidosis by Scintigraphy with 123I-Labeled Serum Amyloid P Component
PN Hawkins, JP Lavender, MB Pepys
New England Journal of Medicine 323 (8), 508-513, 1990
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