| Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3β/β-catenin signaling Y Mao, X Ge, CL Frank, JM Madison, AN Koehler, MK Doud, C Tassa, ... Cell 136 (6), 1017-1031, 2009 | 898 | 2009 |
| Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration KK Singh, KJ Park, EJ Hong, BM Kramer, ME Greenberg, DR Kaplan, ... Nature neuroscience 11 (6), 649-658, 2008 | 271 | 2008 |
| Understanding the role of DISC1 in psychiatric disease and during normal development NJ Brandon, JK Millar, C Korth, H Sive, KK Singh, A Sawa Journal of Neuroscience 29 (41), 12768-12775, 2009 | 253 | 2009 |
| Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits E Kelly, F Meng, H Fujita, F Morgado, Y Kazemi, LC Rice, C Ren, ... Nature neuroscience 23 (9), 1102-1110, 2020 | 177 | 2020 |
| Dixdc1 is a critical regulator of DISC1 and embryonic cortical development KK Singh, X Ge, Y Mao, L Drane, K Meletis, BA Samuels, LH Tsai Neuron 67 (1), 33-48, 2010 | 166 | 2010 |
| Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling M Richter, N Murtaza, R Scharrenberg, SH White, O Johanns, S Walker, ... Molecular psychiatry 24 (9), 1329-1350, 2019 | 145 | 2019 |
| Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development KK Singh, G De Rienzo, L Drane, Y Mao, Z Flood, J Madison, M Ferreira, ... Neuron 72 (4), 545-558, 2011 | 144 | 2011 |
| Complete disruption of autism-susceptibility genes by gene editing predominantly reduces functional connectivity of isogenic human neurons E Deneault, SH White, DC Rodrigues, PJ Ross, M Faheem, K Zaslavsky, ... Stem cell reports 11 (5), 1211-1225, 2018 | 127 | 2018 |
| Wnt signaling networks in autism spectrum disorder and intellectual disability V Kwan, BK Unda, KK Singh Journal of neurodevelopmental disorders 8, 1-10, 2016 | 124 | 2016 |
| Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse JK Atwal, KK Singh, M Tessier-Lavigne, FD Miller, DR Kaplan Journal of Neuroscience 23 (20), 7602-7609, 2003 | 124 | 2003 |
| Activity regulates positive and negative neurotrophin-derived signals to determine axon competition KK Singh, FD Miller Neuron 45 (6), 837-845, 2005 | 92 | 2005 |
| OTUD7A regulates neurodevelopmental phenotypes in the 15q13. 3 microdeletion syndrome M Uddin, BK Unda, V Kwan, NT Holzapfel, SH White, L Chalil, ... The American Journal of Human Genetics 102 (2), 278-295, 2018 | 90 | 2018 |
| Single transcription factor conversion of human blood fate to NPCs with CNS and PNS developmental capacity JH Lee, RR Mitchell, JD McNicol, Z Shapovalova, S Laronde, ... Cell reports 11 (9), 1367-1376, 2015 | 90 | 2015 |
| CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks E Deneault, M Faheem, SH White, DC Rodrigues, S Sun, W Wei, ... Elife 8, e40092, 2019 | 79 | 2019 |
| Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin O Durak, FC de Anda, KK Singh, MP Leussis, TL Petryshen, P Sklar, ... Molecular psychiatry 20 (3), 388-397, 2015 | 78 | 2015 |
| An emerging role for Wnt and GSK3 signaling pathways in schizophrenia KK Singh Clinical genetics 83 (6), 511-517, 2013 | 56 | 2013 |
| A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths CLK Hung, T Maiuri, LE Bowie, R Gotesman, S Son, M Falcone, ... Molecular Biology of the Cell 29 (23), 2809-2820, 2018 | 37 | 2018 |
| Adult skin-derived precursor Schwann cells exhibit superior myelination and regeneration supportive properties compared to chronically denervated nerve-derived Schwann cells R Kumar, S Sinha, A Hagner, M Stykel, E Raharjo, KK Singh, R Midha, ... Experimental neurology 278, 127-142, 2016 | 33 | 2016 |
| DIXDC1 phosphorylation and control of dendritic morphology are impaired by rare genetic variants V Kwan, DP Meka, SH White, CL Hung, NT Holzapfel, S Walker, ... Cell reports 17 (7), 1892-1904, 2016 | 29 | 2016 |
| Report of the first patient with a homozygous OTUD7A variant responsible for epileptic encephalopathy and related proteasome dysfunction P Garret, F Ebstein, G Delplancq, B Dozieres‐Puyravel, A Boughalem, ... Clinical Genetics 97 (4), 567-575, 2020 | 22 | 2020 |
