| Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins LH Gremski, D Trevisan-Silva, VP Ferrer, FH Matsubara, GO Meissner, ... Toxicon 83, 91-120, 2014 | 150 | 2014 |
| Brown spider dermonecrotic toxin directly induces nephrotoxicity OM Chaim, YB Sade, RB da Silveira, L Toma, E Kalapothakis, ... Toxicology and applied pharmacology 211 (1), 64-77, 2006 | 148 | 2006 |
| Identification, cloning, expression and functional characterization of an astacin-like metalloprotease toxin from Loxosceles intermedia (brown spider) venom RB Da Silveira, ACM Wille, OM Chaim, MH Appel, DT Silva, CRC Franco, ... Biochemical Journal 406 (2), 355-363, 2007 | 118 | 2007 |
| A novel expression profile of the Loxosceles intermedia spider venomous gland revealed by transcriptome analysis LH Gremski, RB da Silveira, OM Chaim, CM Probst, VP Ferrer, J Nowatzki, ... Molecular Biosystems 6 (12), 2403-2416, 2010 | 115 | 2010 |
| Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes OM Chaim, D Trevisan-Silva, D Chaves-Moreira, ACM Wille, VP Ferrer, ... Toxins 3 (3), 309-344, 2011 | 112 | 2011 |
| Astacin-like metalloproteases are a gene family of toxins present in the venom of different species of the brown spider (genus Loxosceles) D Trevisan-Silva, LH Gremski, OM Chaim, RB da Silveira, GO Meissner, ... Biochimie 92 (1), 21-32, 2010 | 110 | 2010 |
| Molecular cloning and functional characterization of two isoforms of dermonecrotic toxin from Loxosceles intermedia (brown spider) venom gland RB da Silveira, RB Pigozzo, OM Chaim, MH Appel, JL Dreyfuss, L Toma, ... Biochimie 88 (9), 1241-1253, 2006 | 100 | 2006 |
| Experimental Evidence for a Direct Cytotoxicity of Loxosceles intermedia (Brown Spider) Venom in Renal Tissue MN Luciano, PH da Silva, OM Chaim, VLP dos Santos, CRC Franco, ... Journal of Histochemistry & Cytochemistry 52 (4), 455-467, 2004 | 98 | 2004 |
| A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization VP Ferrer, TL de Mari, LH Gremski, D Trevisan Silva, RB da Silveira, ... PLoS neglected tropical diseases 7 (5), e2206, 2013 | 84 | 2013 |
| Hyaluronidases in Loxosceles intermedia (Brown spider) venom are endo-β-N-acetyl-d-hexosaminidases hydrolases RB da Silveira, OM Chaim, OC Mangili, W Gremski, CP Dietrich, ... Toxicon 49 (6), 758-768, 2007 | 84 | 2007 |
| Two novel dermonecrotic toxins LiRecDT4 and LiRecDT5 from brown spider (Loxosceles intermedia) venom: from cloning to functional characterization RB da Silveira, RB Pigozzo, OM Chaim, MH Appel, DT Silva, JL Dreyfuss, ... Biochimie 89 (3), 289-300, 2007 | 81 | 2007 |
| Identification, cloning and functional characterization of a novel dermonecrotic toxin (phospholipase D) from brown spider (Loxosceles intermedia) venom MH Appel, RB da Silveira, OM Chaim, KS Paludo, DT Silva, DM Chaves, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (2), 167-178, 2008 | 80 | 2008 |
| Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity J Kusma, OM Chaim, ACM Wille, VP Ferrer, YB Sade, L Donatti, ... Biochimie 90 (11-12), 1722-1736, 2008 | 77 | 2008 |
| Biotechnological applications of brown spider (Loxosceles genus) venom toxins A Senff-Ribeiro, PH da Silva, OM Chaim, LH Gremski, KS Paludo, ... Biotechnology advances 26 (3), 210-218, 2008 | 69 | 2008 |
| Identification of a direct hemolytic effect dependent on the catalytic activity induced by phospholipase‐D (dermonecrotic toxin) from brown spider venom D Chaves‐Moreira, OM Chaim, YB Sade, KS Paludo, LH Gremski, ... Journal of cellular biochemistry 107 (4), 655-666, 2009 | 64 | 2009 |
| Analysis of therapeutic benefits of antivenin at different time intervals after experimental envenomation in rabbits by venom of the brown spider (Loxosceles intermedia) I Pauli, JC Minozzo, PH da Silva, OM Chaim, SS Veiga Toxicon 53 (6), 660-671, 2009 | 64 | 2009 |
| The relationship between calcium and the metabolism of plasma membrane phospholipids in hemolysis induced by brown spider venom phospholipase‐D toxin D Chaves‐Moreira, FN Souza, RTH Fogaça, OC Mangili, W Gremski, ... Journal of cellular biochemistry 112 (9), 2529-2540, 2011 | 62 | 2011 |
| Phospholipase-D activity and inflammatory response induced by brown spider dermonecrotic toxin: endothelial cell membrane phospholipids as targets for toxicity OM Chaim, RB da Silveira, D Trevisan-Silva, VP Ferrer, YB Sade, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2011 | 62 | 2011 |
| Biological and structural comparison of recombinant phospholipase D toxins from Loxosceles intermedia (brown spider) venom ROS Ribeiro, OM Chaim, RB da Silveira, LH Gremski, YB Sade, ... Toxicon 50 (8), 1162-1174, 2007 | 62 | 2007 |
| YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity OM Yu, JA Benitez, SW Plouffe, D Ryback, A Klein, J Smith, J Greenbaum, ... Oncogene 37 (41), 5492-5507, 2018 | 61 | 2018 |
Dilza Trevisan SilvaAssistant Director, Biomolecular Analysis Facility, University of Virginia.E-mail confirmado em virginia.edu
