| Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ... Genes & development 16 (7), 846-858, 2002 | 847 | 2002 |
| Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects DB Donoviel, AK Hadjantonakis, M Ikeda, H Zheng, PSG Hyslop, ... Genes & development 13 (21), 2801-2810, 1999 | 589 | 1999 |
| Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN DB Donoviel, DD Freed, H Vogel, DG Potter, E Hawkins, JP Barrish, ... Molecular and cellular biology 21 (14), 4829-4836, 2001 | 550 | 2001 |
| Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1 Z Zhang, P Nadeau, W Song, D Donoviel, M Yuan, A Bernstein, ... Nature cell biology 2 (7), 463-465, 2000 | 526 | 2000 |
| mdmx is a negative regulator of p53 activity in vivo RA Finch, DB Donoviel, D Potter, M Shi, A Fan, DD Freed, C Wang, ... Cancer research 62 (11), 3221-3225, 2002 | 258 | 2002 |
| Presenilin-1 and presenilin-2 exhibit distinct yet overlapping γ-secretase activities MT Lai, E Chen, MC Crouthamel, J DiMuzio-Mower, M Xu, Q Huang, ... Journal of Biological Chemistry 278 (25), 22475-22481, 2003 | 209 | 2003 |
| Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression N Sato, F Urano, J Yoon Leem, SH Kim, M Li, D Donoviel, A Bernstein, ... Nature cell biology 2 (12), 863-870, 2000 | 159 | 2000 |
| Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice A Shiels, S Bassnett, K Varadaraj, R Mathias, K Al-Ghoul, J Kuszak, ... Physiological genomics 7 (2), 179-186, 2001 | 158 | 2001 |
| Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice DB Donoviel, MA Shield, JN Buskin, HS Haugen, CH Clegg, ... Molecular and cellular biology, 1996 | 126 | 1996 |
| Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice G Donoho, MA Brenneman, TX Cui, D Donoviel, H Vogel, EH Goodwin, ... Genes, Chromosomes and Cancer 36 (4), 317-331, 2003 | 117 | 2003 |
| The impact of sex and gender on adaptation to space: executive summary S Mark, GBI Scott, DB Donoviel, LB Leveton, E Mahoney, JB Charles, ... Journal of women's health 23 (11), 941-947, 2014 | 93 | 2014 |
| Notch receptor cleavage depends on but is not directly executed by presenilins Y Taniguchi, H Karlström, J Lundkvist, T Mizutani, A Otaka, M Vestling, ... Proceedings of the National Academy of Sciences 99 (6), 4014-4019, 2002 | 80 | 2002 |
| Identification and characterization of presenilin-independent Notch signaling BE Berechid, M Kitzmann, DR Foltz, AH Roach, D Seiffert, LA Thompson, ... Journal of Biological Chemistry 277 (10), 8154-8165, 2002 | 71 | 2002 |
| High‐throughput screening of mouse knockout lines identifies true lean and obese phenotypes R Brommage, U Desai, JP Revelli, DB Donoviel, GK Fontenot, ... Obesity 16 (10), 2362-2367, 2008 | 62 | 2008 |
| Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor DB Donoviel, SL Amacher, KW Judge, P Bornstein Journal of cellular physiology 145 (1), 16-23, 1990 | 60 | 1990 |
| Structural analysis and expression of the human thrombospondin gene promoter. DB Donoviel, P Framson, CF Eldridge, M Cooke, S Kobayashi, ... Journal of Biological Chemistry 263 (35), 18590-18593, 1988 | 58 | 1988 |
| Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene DB Donoviel, MS Donoviel, E Fan, AK Hadjantonakis, A Bernstein Mechanisms of development 78 (1-2), 203-207, 1998 | 56 | 1998 |
| Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling T Takeda, M Asahi, O Yamaguchi, S Hikoso, H Nakayama, Y Kusakari, ... The FASEB journal 19 (14), 2069-2071, 2005 | 54 | 2005 |
| Functional characterization of novel presenilin-2 variants identified in human breast cancers MD To, N Gokgoz, TG Doyle, DB Donoviel, JA Knight, PS Hyslop, ... Oncogene 25 (25), 3557-3564, 2006 | 50 | 2006 |
| Novel indications for commonly used medications as radiation protectants in spaceflight MF McLaughlin, DB Donoviel, JA Jones Aerospace medicine and human performance 88 (7), 665-676, 2017 | 38 | 2017 |
