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Christopher Mariani
Christopher Mariani
Massachusetts General Hospital
E-mail confirmado em partners.org
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Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy
MY Zhang, JE Churpek, SB Keel, T Walsh, MK Lee, KR Loeb, S Gulsuner, ...
Nature genetics 47 (2), 180-185, 2015
4082015
Fumarate and succinate regulate expression of hypoxia-inducible genes via TET enzymes
T Laukka, CJ Mariani, T Ihantola, JZ Cao, J Hokkanen, WG Kaelin, ...
Journal of Biological Chemistry 291 (8), 4256-4265, 2016
3092016
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma
CJ Mariani, A Vasanthakumar, J Madzo, A Yesilkanal, T Bhagat, Y Yu, ...
Cell reports 7 (5), 1343-1352, 2014
1782014
Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann− Pick type C disease therapeutics
AI Rosenbaum, CC Cosner, CJ Mariani, FR Maxfield, O Wiest, P Helquist
Journal of medicinal chemistry 53 (14), 5281-5289, 2010
1012010
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer
CG Chapman, CJ Mariani, F Wu, K Meckel, F Butun, A Chuang, J Madzo, ...
Scientific reports 5 (1), 17568, 2015
702015
New themes in the biological functions of 5‐methylcytosine and 5‐hydroxymethylcytosine
EL Moen, CJ Mariani, H Zullow, M Jeff‐Eke, E Litwin, JN Nikitas, ...
Immunological reviews 263 (1), 36-49, 2015
592015
Alterations of 5-hydroxymethylcytosine in human cancers
CJ Mariani, J Madzo, EL Moen, A Yesilkanal, LA Godley
Cancers 5 (3), 786-814, 2013
502013
Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients
MA Applebaum, AR Jha, C Kao, KM Hernandez, G DeWane, HR Salwen, ...
Oncotarget 7 (47), 76816, 2016
372016
Investigation of N-Aryl-3-alkylidenepyrrolinones as Potential Niemann−Pick Type C Disease Therapeutics
CC Cosner, JT Markiewicz, P Bourbon, CJ Mariani, O Wiest, M Rujoi, ...
Journal of medicinal chemistry 52 (20), 6494-6498, 2009
362009
Recent developments in the synthesis of 1, 2, 5-thiadiazoles and 2, 1, 3-benzothiadiazoles
OA Rakitin
Synthesis 51 (23), 4338-4347, 2019
312019
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer (vol 5, 17568, 2015)
CG Chapman, CJ Mariani, F Wu, K Meckel, F Butun, A Chuang, J Madzo, ...
SCIENTIFIC REPORTS 6, 2016
2016
Abstract A01: Evaluation of hypoxia adaptation in neuroblastoma identifies reproducible transcriptional and phenotypic responses
MA Aplebaum, A Jha, A Chlenski, C Mariani, C Kao, M Nelson, ...
Cancer Research 76 (5_Supplement), A01-A01, 2016
2016
EVALUATION OF HYPOXIA ADAPTATION IN NEUROBLASTOMA IDENTIFIES REPRODUCIBLE TRANSCRIPTIONAL AND PHENOTYPIC RESPONSES
MA Applebaum, A Jha, C Mariani, K White, B Stranger, S Cohn
CLINICAL PHARMACOLOGY & THERAPEUTICS 99, S30-S31, 2016
2016
Identification of evolutionarily conserved hypoxia-induced genomic pathways responsible for aggressive neuroblastoma phenotypes
MA Applebaum, AR Jha, A Chlenski, K Hernandez, CJ Mariani, ...
CANCER RESEARCH 75 (22), 2015
2015
IDENTIFICATION OF CONSERVED HYPOXIA-INDUCED GENOMIC PATHWAYS THAT DRIVE AGGRESSIVE NEUROBLASTOMA PHENOTYPES
MA Applebaum, AR Jha, K Hernandez, CJ Mariani, BE Stranger, SL Cohn
CLINICAL PHARMACOLOGY & THERAPEUTICS 97, S30-S30, 2015
2015
Chromosomal Dynamics and Stability
CJ MARIANI, EL MOEN, T MACRAE, M DAUNOV, KR OSTLER, ...
Cancer Biology Review: A Case-Based Approach, 45, 2013
2013
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