Juan A. Varela
Juan A. Varela
Reader in Biophysics and Biophotonics, University of St Andrews
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FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
S Qamar*, GZ Wang*, SJ Randle*, FS Ruggeri*, JA Varela*, JQ Lin*, ...
Cell 173 (3), 720-734. e15, 2018
Effects of transport inhibitors on the cellular uptake of carboxylated polystyrene nanoparticles in different cell lines
T Dos Santos, J Varela, I Lynch, A Salvati, KA Dawson
PloS one 6 (9), e24438, 2011
Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics
A Salvati, C Åberg, T dos Santos, J Varela, P Pinto, I Lynch, KA Dawson
Nanomedicine: Nanotechnology, Biology and Medicine 7 (6), 818-826, 2011
Quantitative assessment of the comparative nanoparticle‐uptake efficiency of a range of cell lines
T Dos Santos, J Varela, I Lynch, A Salvati, KA Dawson
Small 7 (23), 3341-3349, 2011
Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission
C Murphy-Royal, JP Dupuis, JA Varela, A Panatier, B Pinson, J Baufreton, ...
Nature neuroscience 18 (2), 219-226, 2015
Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain
AG Godin*, JA Varela*, Z Gao*, N Danné, JP Dupuis, B Lounis, L Groc, ...
Nature nanotechnology 12 (3), 238-243, 2017
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ...
Nature communications 10 (1), 1541, 2019
Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells
JA Varela, MG Bexiga, C Åberg, JC Simpson, KA Dawson
Journal of nanobiotechnology 10 (1), 1-6, 2012
Cationic nanoparticles induce caspase 3-, 7-and 9-mediated cytotoxicity in a human astrocytoma cell line
MG Bexiga, JA Varela, F Wang, F Fenaroli, A Salvati, I Lynch, JC Simpson, ...
Nanotoxicology 5 (4), 557-567, 2011
Surface dynamics of G lu N 2 B‐NMDA receptors controls plasticity of maturing glutamate synapses
JP Dupuis, L Ladépêche, H Seth, L Bard, J Varela, L Mikasova, ...
The EMBO journal 33 (8), 842-861, 2014
Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
JA Varela, JP Dupuis, L Etchepare, A Espana, L Cognet, L Groc
Nature communications 7 (1), 10947, 2016
Hyper-bright near-infrared emitting fluorescent organic nanoparticles for single particle tracking
E Genin, Z Gao, JA Varela, J Daniel, T Bsaibess, I Gosse, L Groc, ...
Advanced Materials 26 (14), 2258-2261, 2014
ThX–a next-generation probe for the early detection of amyloid aggregates
LM Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, ...
Chemical Science 11 (18), 4578-4583, 2020
Toward the suppression of cellular toxicity from single-walled carbon nanotubes
Z Gao, JA Varela, L Groc, B Lounis, L Cognet
Biomaterials science 4 (2), 230-244, 2016
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, ...
Angewandte Chemie 130 (18), 4980-4984, 2018
Comparative analysis of photoluminescence and upconversion emission from individual carbon nanotubes for bioimaging applications
N Danné, AG Godin, Z Gao, JA Varela, L Groc, B Lounis, L Cognet
ACS photonics 5 (2), 359-364, 2018
Single nanoparticle tracking of N-methyl-D-aspartate receptors in cultured and intact brain tissue
JA Varela*, JS Ferreira*, JP Dupuis*, P Durand, D Bouchet, L Groc
Neurophotonics 3 (4), 041808-041808, 2016
Trajectory‐Based Co‐Localization Measures for Nanoparticle‐Cell Interaction Studies
JA Varela, C Åberg, JC Simpson, KA Dawson
Small 11 (17), 2026-2031, 2015
Spatial and structural metrics for living cells inspired by statistical mechanics
C Åberg*, JA Varela*, LW Fitzpatrick, KA Dawson
Scientific reports 6 (1), 34457, 2016
Two-layer stratified flows over pronounced obstacles at low-to-intermediate Froude numbers
C Cabeza, J Varela, I Bove, D Freire, AC Martí, LG Sarasua, G Usera, ...
Physics of fluids 21 (4), 2009
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Artigos 1–20