Brian Kennedy
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Geroscience: linking aging to chronic disease
BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ...
Cell 159 (4), 709-713, 2014
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
M Kaeberlein, RW Powers III, KK Steffen, EA Westman, D Hu, N Dang, ...
Science 310 (5751), 1193-1196, 2005
Extension of chronological life span in yeast by decreased TOR pathway signaling
RW Powers, M Kaeberlein, SD Caldwell, BK Kennedy, S Fields
Genes & development 20 (2), 174-184, 2006
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ...
Cancer discovery 7 (2), 165-176, 2017
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ...
Cell metabolism 19 (3), 407-417, 2014
Substrate-specific activation of sirtuins by resveratrol
M Kaeberlein, T McDonagh, B Heltweg, J Hixon, EA Westman, ...
Journal of Biological Chemistry 280 (17), 17038-17045, 2005
A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan
S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ...
Cell metabolism 22 (1), 86-99, 2015
Sirtuins in aging and age-related disease
VD Longo, BK Kennedy
Cell 126 (2), 257-268, 2006
Histone H4 lysine 16 acetylation regulates cellular lifespan
W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ...
Nature 459 (7248), 802-807, 2009
Replicative and chronological aging in Saccharomyces cerevisiae
VD Longo, GS Shadel, M Kaeberlein, B Kennedy
Cell metabolism 16 (1), 18-31, 2012
Interventions to slow aging in humans: are we ready?
VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ...
Aging cell 14 (4), 497-510, 2015
Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae
BK Kennedy, NR Austriaco Jr, J Zhang, L Guarente
Cell 80 (3), 485-496, 1995
Sir2-independent life span extension by calorie restriction in yeast
M Kaeberlein, KT Kirkland, S Fields, BK Kennedy
PLoS biology 2 (9), e296, 2004
The mechanistic target of rapamycin: the grand conducTOR of metabolism and aging
BK Kennedy, DW Lamming
Cell metabolism 23 (6), 990-1003, 2016
The TOR pathway comes of age
MN Stanfel, LS Shamieh, M Kaeberlein, BK Kennedy
Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1067-1074, 2009
LMNA mutations in atypical Werner's syndrome
L Chen, L Lee, BA Kudlow, HG Dos Santos, O Sletvold, Y Shafeghati, ...
The Lancet 362 (9382), 440-445, 2003
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4
KK Steffen, VL MacKay, EO Kerr, M Tsuchiya, D Hu, LA Fox, N Dang, ...
Cell 133 (2), 292-302, 2008
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae
BK Kennedy, M Gotta, DA Sinclair, K Mills, DS McNabb, M Murthy, ...
Cell 89 (3), 381-391, 1997
Progeria syndromes and ageing: what is the connection?
CR Burtner, BK Kennedy
Nature reviews Molecular cell biology 11 (8), 567-578, 2010
NPAT links cyclin E–Cdk2 to the regulation of replication-dependent histone gene transcription
J Zhao, BK Kennedy, BD Lawrence, DA Barbie, AG Matera, JA Fletcher, ...
Genes & development 14 (18), 2283-2297, 2000
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