Siddharthan Chandran
Siddharthan Chandran
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Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ...
Nature neuroscience 14 (4), 452-458, 2011
A new method for the rapid and long term growth of human neural precursor cells
CN Svendsen, MG ter Borg, RJE Armstrong, AE Rosser, S Chandran, ...
Journal of neuroscience methods 85 (2), 141-152, 1998
Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study
P Connick, M Kolappan, C Crawley, DJ Webber, R Patani, AW Michell, ...
The Lancet Neurology 11 (2), 150-156, 2012
Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations
NH Alami, RB Smith, MA Carrasco, LA Williams, CS Winborn, SSW Han, ...
Neuron 81 (3), 536-543, 2014
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms: a novel role for oligodendrocyte-derived glial cell line-derived neurotrophic …
A Wilkins, H Majed, R Layfield, A Compston, S Chandran
Journal of Neuroscience 23 (12), 4967-4974, 2003
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
SJ Barmada, A Serio, A Arjun, B Bilican, A Daub, DM Ando, A Tsvetkov, ...
Nature chemical biology 10 (8), 677-685, 2014
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ...
Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
A Serio, B Bilican, SJ Barmada, DM Ando, C Zhao, R Siller, K Burr, ...
Proceedings of the National Academy of Sciences 110 (12), 4697-4702, 2013
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis
PL Foley, HM Vesterinen, BJ Laird, ES Sena, LA Colvin, S Chandran, ...
PAIN® 154 (5), 632-642, 2013
Efficient generation of neural precursors from adult human skin: astrocytes promote neurogenesis from skin-derived stem cells
A Joannides, P Gaughwin, C Schwiening, H Majed, J Sterling, ...
The Lancet 364 (9429), 172-178, 2004
FUS-SMN protein interactions link the motor neuron diseases ALS and SMA
T Yamazaki, S Chen, Y Yu, B Yan, TC Haertlein, MA Carrasco, JC Tapia, ...
Cell reports 2 (4), 799-806, 2012
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
AC Devlin, K Burr, S Borooah, JD Foster, EM Cleary, I Geti, L Vallier, ...
Nature communications 6 (1), 1-12, 2015
Modeling ALS with motor neurons derived from human induced pluripotent stem cells
S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ...
Nature neuroscience 19 (4), 542-553, 2016
Lineage-specific distribution of high levels of genomic
A Ruzov, Y Tsenkina, A Serio, T Dudnakova, J Fletcher, Y Bai, ...
Cell research 21 (9), 1332-1342, 2011
A role for oligodendrocyte‐derived IGF‐1 in trophic support of cortical neurons
A Wilkins, S Chandran, A Compston
Glia 36 (1), 48-57, 2001
Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells
L Vallier, T Touboul, S Brown, C Cho, B Bilican, M Alexander, J Cedervall, ...
Stem cells 27 (11), 2655-2666, 2009
A highly enriched niche of precursor cells with neuronal and glial potential within the hair follicle dermal papilla of adult skin
DPJ Hunt, PN Morris, J Sterling, JA Anderson, A Joannides, C Jahoda, ...
Stem cells 26 (1), 163-172, 2008
Improving the translational hit of experimental treatments in multiple sclerosis
HM Vesterinen, ES Sena, C Ffrench-Constant, A Williams, S Chandran, ...
Multiple Sclerosis Journal 16 (9), 1044-1055, 2010
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