Justin Hines
Justin Hines
David M. '70 and Linda Roth Professor of Chemistry, Lafayette College
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Specificity of the J-protein Sis1 in the propagation of 3 yeast prions
T Higurashi, JK Hines, C Sahi, R Aron, EA Craig
Proceedings of the National Academy of Sciences 105 (43), 16596-16601, 2008
[SWI+], the Prion Formed by the Chromatin Remodeling Factor Swi1, Is Highly Sensitive to Alterations in Hsp70 Chaperone System Activity
JK Hines, X Li, Z Du, T Higurashi, L Li, EA Craig
PLoS genetics 7 (2), e1001309, 2011
Novel allosteric activation site in Escherichia coli fructose-1, 6-bisphosphatase
JK Hines, HJ Fromm, RB Honzatko
Journal of Biological Chemistry 281 (27), 18386-18393, 2006
Structure of inhibited fructose-1, 6-bisphosphatase from Escherichia coli: distinct allosteric inhibition sites for AMP and glucose 6-phosphate and the characterization of a …
JK Hines, CE Kruesel, HJ Fromm, RB Honzatko
Journal of Biological Chemistry 282 (34), 24697-24706, 2007
Functional diversification of hsp40: distinct j-protein functional requirements for two prions allow for chaperone-dependent prion selection
JM Harris, PP Nguyen, MJ Patel, ZA Sporn, JK Hines
PLoS genetics 10 (7), e1004510, 2014
Structures of activated fructose-1, 6-bisphosphatase from Escherichia coli: coordinate regulation of bacterial metabolism and the conservation of the r-state
JK Hines, HJ Fromm, RB Honzatko
Journal of Biological Chemistry 282 (16), 11696-11704, 2007
Broadening the functionality of a J-protein/Hsp70 molecular chaperone system
BA Schilke, SJ Ciesielski, T Ziegelhoffer, E Kamiya, M Tonelli, W Lee, ...
PLoS genetics 13 (10), e1007084, 2017
Influence of prion variant and yeast strain variation on prion-molecular chaperone requirements
JK Hines, T Higurashi, M Srinivasan, EA Craig
Prion 5 (4), 238-244, 2011
Swa2, the yeast homolog of mammalian auxilin, is specifically required for the propagation of the prion variant [URE3‐1]
EM Troisi, ME Rockman, PP Nguyen, EE Oliver, JK Hines
Molecular microbiology 97 (5), 926-941, 2015
Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity
ZA Sporn, JK Hines
Prion 9 (2), 80-89, 2015
Low-dose immune challenges result in detectable levels of oxidative damage
EM Armour, TL Bruner, JK Hines, MW Butler
Journal of Experimental Biology 223 (6), jeb220095, 2020
Variant‐specific and reciprocal Hsp40 functions in Hsp104‐mediated prion elimination
MT Astor, E Kamiya, ZA Sporn, SE Berger, JK Hines
Molecular Microbiology 109 (1), 41-62, 2018
Structures of mammalian and bacterial fructose-1, 6-bisphosphatase reveal the basis for synergism in AMP/fructose 2, 6-bisphosphate inhibition
JK Hines, X Chen, JC Nix, HJ Fromm, RB Honzatko
Journal of Biological Chemistry 282 (49), 36121-36131, 2007
Evolutionary Conservation and Emerging Functional Diversity of the Cytosolic Hsp70:J Protein Chaperone Network of Arabidopsis thaliana
AK Verma, D Diwan, S Raut, N Dobriyal, RE Brown, V Gowda, JK Hines, ...
G3: Genes, Genomes, Genetics 7 (6), 1941-1954, 2017
The expanding world of plant J-domain proteins
AK Verma, C Tamadaddi, Y Tak, SS Lal, SJ Cole, JK Hines, C Sahi
Critical reviews in plant sciences 38 (5-6), 382-400, 2019
The sensitive [SWI+] prion: New perspectives on yeast prion diversity
JK Hines, EA Craig
Prion 5 (3), 164-168, 2011
Three J-proteins impact Hsp104-mediated variant-specific prion elimination: a new critical role for a low-complexity domain
SE Berger, AM Nolte, E Kamiya, JK Hines
Current genetics 66 (1), 51-58, 2020
Impact of amyloid polymorphism on prion-chaperone interactions in yeast
AN Killian, SC Miller, JK Hines
Viruses 11 (4), 349, 2019
Chaperone functional specificity promotes yeast prion diversity
AN Killian, JK Hines
PLoS pathogens 14 (1), e1006695, 2018
Prion-specific Hsp40 function: The role of the auxilin homolog Swa2
EE Oliver, EM Troisi, JK Hines
Prion 11 (3), 174-185, 2017
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