The prodrug approach: A successful tool for improving drug solubility DH Jornada, GF dos Santos Fernandes, DE Chiba, TRF De Melo, ... Molecules 21 (1), 42, 2015 | 271 | 2015 |
Advances in prodrug design AT de Albuquerque Silva, MC Chung, LF Castro, RV Carvalho Guido, ... Mini reviews in medicinal chemistry 5 (10), 893-914, 2005 | 136 | 2005 |
Interações medicamentosas de fitoterápicos e fármacos: Hypericum perforatum e Piper methysticum CHG Cordeiro, MC Chung, LVS Do Sacramento Revista Brasileira de Farmacognosia 15, 272-278, 2005 | 129 | 2005 |
Synthesis and in vitro anti Mycobacterium tuberculosis activity of a series of phthalimide derivatives JL Santos, PR Yamasaki, CM Chin, CH Takashi, FR Pavan, CQF Leite Bioorganic & medicinal chemistry 17 (11), 3795-3799, 2009 | 126 | 2009 |
Unraveling the anticancer effect of curcumin and resveratrol AR Pavan, GDB Silva, DH Jornada, DE Chiba, GFS Fernandes, ... Nutrients 8 (11), 628, 2016 | 118 | 2016 |
Synthesis and in vitro evaluation of potential antichagasic hydroxymethylnitrofurazone (NFOH-121): a new nitrofurazone prodrug MC Chung, RVC Güido, TF Martinelli, MF Gonçalves, MC Polli, ... Bioorganic & medicinal chemistry 11 (22), 4779-4783, 2003 | 111 | 2003 |
Current advances in drug discovery for Chagas disease CB Scarim, DH Jornada, RC Chelucci, L de Almeida, JL Dos Santos, ... European journal of medicinal chemistry 155, 824-838, 2018 | 105 | 2018 |
Epigenetic regulatory mechanisms induced by resveratrol GFS Fernandes, GDB Silva, AR Pavan, DE Chiba, CM Chin, ... Nutrients 9 (11), 1201, 2017 | 105 | 2017 |
Prodrugs for the treatment of neglected diseases MC Chung, EI Ferreira, JL Santos, J Giarolla, DG Rando, AE Almeida, ... Molecules 13 (3), 616-677, 2008 | 102 | 2008 |
Anti-inflammatory drug design using a molecular hybridization approach PL Bosquesi, TRF Melo, EO Vizioli, JL Santos, MC Chung Pharmaceuticals 4 (11), 1450-1474, 2011 | 97 | 2011 |
Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis GF dos Santos Fernandes, PC de Souza, LB Marino, K Chegaev, ... European Journal of Medicinal Chemistry 123, 523-531, 2016 | 88 | 2016 |
A prodrug approach to improve the physico-chemical properties and decrease the genotoxicity of nitro compounds M Chin Chung, P Longhin Bosquesi, J Leandro dos Santos Current pharmaceutical design 17 (32), 3515-3526, 2011 | 72 | 2011 |
Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria CB Scarim, DH Jornada, MGM Machado, CMR Ferreira, JL Dos Santos, ... European journal of medicinal chemistry 162, 378-395, 2019 | 71 | 2019 |
O processo de latenciação no planejamento de fármacos MC Chung, EI Ferreira Química Nova 22, 75-84, 1999 | 70 | 1999 |
Design, Synthesis, and Pharmacological Evaluation of Novel Hybrid Compounds to Treat Sickle Cell Disease Symptoms. Part II: Furoxan Derivatives JL Dos Santos, C Lanaro, RC Chelucci, S Gambero, PL Bosquesi, ... Journal of Medicinal Chemistry 55 (17), 7583-7592, 2012 | 67 | 2012 |
Design, synthesis, and characterization of N-oxide-containing heterocycles with in vivo sterilizing antitubercular activity GF dos Santos Fernandes, PC De Souza, E Moreno-Viguri, ... Journal of Medicinal Chemistry 60 (20), 8647-8660, 2017 | 64 | 2017 |
Advances in drug discovery of new antitubercular multidrug-resistant compounds GFS Fernandes, C Man Chin, JL Dos Santos Pharmaceuticals 10 (2), 51, 2017 | 58 | 2017 |
Leishmanicidal activities of novel synthetic furoxan and benzofuroxan derivatives LA Dutra, L de Almeida, TG Passalacqua, JS Reis, FAE Torres, I Martinez, ... Antimicrobial Agents and Chemotherapy 58 (8), 4837-4847, 2014 | 58 | 2014 |
Qualidade dos medicamentos contendo dipirona encontrados nas residências de Araraquara e sua relação com a atenção farmacêutica EOP Serafim, A Del Vecchio, J Gomes, A Miranda, AH Moreno, ... Revista Brasileira de Ciências Farmacêuticas 43, 127-135, 2007 | 58 | 2007 |
Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms JL dos Santos, C Lanaro, LM Lima, S Gambero, CF Franco-Penteado, ... Journal of medicinal chemistry 54 (16), 5811-5819, 2011 | 54 | 2011 |