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alison simmons
alison simmons
Director, MRC Human Immunology Unit, UK. Professor of Gastroenterology, University of Oxford.
E-mail confirmado em imm.ox.ac.uk - Página inicial
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107642021
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ...
Nature genetics 47 (9), 979-986, 2015
24222015
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
R Cooney, J Baker, O Brain, B Danis, T Pichulik, P Allan, DJP Ferguson, ...
Nature medicine 16 (1), 90-97, 2010
12912010
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
12002017
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
NR West, AN Hegazy, BMJ Owens, SJ Bullers, B Linggi, S Buonocore, ...
Nature medicine 23 (5), 579-589, 2017
6702017
Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
H Chu, A Khosravi, IP Kusumawardhani, AHK Kwon, AC Vasconcelos, ...
Science 352 (6289), 1116-1120, 2016
5932016
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
5662019
Colonic epithelial cell diversity in health and inflammatory bowel disease
K Parikh, A Antanaviciute, D Fawkner-Corbett, M Jagielowicz, A Aulicino, ...
Nature 567 (7746), 49-55, 2019
5622019
Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease
J Kinchen, HH Chen, K Parikh, A Antanaviciute, M Jagielowicz, ...
Cell 175 (2), 372-386. e17, 2018
5242018
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ...
Nature genetics 47 (7), 717-726, 2015
4042015
Pattern of neuronal activity associated with conscious and unconscious processing of visual signals
A Sahraie, L Weiskrantz, JL Barbur, A Simmons, SCR Williams, ...
Proceedings of the National Academy of Sciences 94 (17), 9406-9411, 1997
3771997
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
A Simmons, V Aluvihare, A McMichael
Immunity 14 (6), 763-777, 2001
3632001
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
3302015
The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing
NA Kennedy, AW Walker, SH Berry, SH Duncan, FM Farquarson, P Louis, ...
PloS one 9 (2), e88982, 2014
3282014
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020
3082020
Spatiotemporal analysis of human intestinal development at single-cell resolution
D Fawkner-Corbett, A Antanaviciute, K Parikh, M Jagielowicz, AS Gerós, ...
Cell 184 (3), 810-826. e23, 2021
3012021
Circulating and tissue-resident CD4+ T cells with reactivity to intestinal microbiota are abundant in healthy individuals and function is altered during inflammation
AN Hegazy, NR West, MJT Stubbington, E Wendt, KIM Suijker, A Datsi, ...
Gastroenterology 153 (5), 1320-1337. e16, 2017
2962017
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
JC Lee, D Biasci, R Roberts, RB Gearry, JC Mansfield, T Ahmad, ...
Nature genetics 49 (2), 262-268, 2017
2602017
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway
JC Lee, M Espéli, CA Anderson, MA Linterman, JM Pocock, NJ Williams, ...
Cell 155 (1), 57-69, 2013
2602013
Embedded EthiCS: integrating ethics across CS education
BJ Grosz, DG Grant, K Vredenburgh, J Behrends, L Hu, A Simmons, ...
Communications of the ACM 62 (8), 54-61, 2019
2422019
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