Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis LS Poritz, KI Garver, C Green, L Fitzpatrick, F Ruggiero, WA Koltun Journal of Surgical Research 140 (1), 12-19, 2007 | 480 | 2007 |
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses WW Reiley, W Jin, AJ Lee, A Wright, X Wu, EF Tewalt, TO Leonard, ... The Journal of experimental medicine 204 (6), 1475-1485, 2007 | 285 | 2007 |
Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase LW Maines, LR Fitzpatrick, KJ French, Y Zhuang, Z Xia, SN Keller, ... Digestive diseases and sciences 53, 997-1012, 2008 | 206 | 2008 |
Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review A Salaritabar, B Darvishi, F Hadjiakhoondi, A Manayi, A Sureda, ... World journal of gastroenterology 23 (28), 5097, 2017 | 186 | 2017 |
Caffeic acid phenethyl ester, an inhibitor of nuclear factor-κB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats LR Fitzpatrick, J Wang, T Le Journal of Pharmacology and Experimental Therapeutics 299 (3), 915-920, 2001 | 114 | 2001 |
Le T. Caffeic acid phenethyl ester, an inhibitor of nuclear factor-kappaB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats LR Fitzpatrick, J Wang J Pharmacol Exp Ther 299 (3), 915-20, 2001 | 98 | 2001 |
Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn’s disease LW Maines, LR Fitzpatrick, CL Green, Y Zhuang, CD Smith Inflammopharmacology 18, 73-85, 2010 | 93 | 2010 |
MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease S Banerjee, B Oneda, LM Yap, DP Jewell, GL Matters, LR Fitzpatrick, ... Mucosal immunology 2 (3), 220-231, 2009 | 87 | 2009 |
OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability A Banan, L Fitzpatrick, Y Zhang, A Keshavarzian Free Radical Biology and Medicine 30 (3), 287-298, 2001 | 81 | 2001 |
4SC-101, a novel immunosuppressive drug, inhibits IL-17 and attenuates colitis in two murine models of inflammatory bowel disease† LR Fitzpatrick, L Deml, C Hofmann, JS Small, M Groeppel, S Hamm, ... Inflammatory bowel diseases 16 (10), 1763-1777, 2010 | 74 | 2010 |
Antiinflammatory effects of various drugs on acetic acid induced colitis in the rat LR Fitzpatrick, JS Bostwick, M Renzetti, RG Pendleton, DL Decktor Agents and actions 30, 393-402, 1990 | 71 | 1990 |
In vitro and in vivo effects of the probiotic Escherichia coli strain M-17: immunomodulation and attenuation of murine colitis LR Fitzpatrick, J Small, RA Hoerr, EF Bostwick, L Maines, WA Koltun British journal of nutrition 100 (3), 530-541, 2008 | 69 | 2008 |
Probiotics for the treatment of Clostridium difficile associated disease LR Fitzpatrick World Journal of Gastrointestinal Pathophysiology 4 (3), 47, 2013 | 68 | 2013 |
Novel pharmacological approaches for inflammatory bowel disease: targeting key intracellular pathways and the IL-23/IL-17 axis LR Fitzpatrick International Journal of Inflammation 2012, 2012 | 67 | 2012 |
In vitro and in vivo effects of gliotoxin, a fungal metabolite LR Fitzpatrick, J Wang, T Le Digestive diseases and sciences 45, 2327-2336, 2000 | 66 | 2000 |
Effects of the probiotic formulation VSL# 3 on colitis in weanling rats LR Fitzpatrick, KL Hertzog, AL Quatse, WA Koltun, JS Small, K Vrana Journal of pediatric gastroenterology and nutrition 44 (5), 561-570, 2007 | 65 | 2007 |
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase LR Fitzpatrick, C Green, EE Frauenhoffer, KJ French, Y Zhuang, ... Inflammopharmacology 19, 75-87, 2011 | 63 | 2011 |
NF-κB1 p105 regulates T cell homeostasis and prevents chronic inflammation M Chang, AJ Lee, L Fitzpatrick, M Zhang, SC Sun The Journal of Immunology 182 (5), 3131-3138, 2009 | 61 | 2009 |
Inhibition of IL-17 as a pharmacological approach for IBD LR Fitzpatrick International reviews of immunology 32 (5-6), 544-555, 2013 | 59 | 2013 |
Dextran sulfate sodium-induced colitis is associated with enhanced low molecular mass polypeptide 2 (LMP2) expression and is attenuated in LMP2 knockout mice LR Fitzpatrick, V Khare, JS Small, WA Koltun Digestive diseases and sciences 51, 1269-1276, 2006 | 54 | 2006 |