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Leonie Young
Leonie Young
E-mail confirmado em rcsi.ie
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Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15, 1-37, 2013
5032013
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised …
P Dandona, C Mathieu, M Phillip, L Hansen, SC Griffen, D Tschöpe, ...
The lancet Diabetes & endocrinology 5 (11), 864-876, 2017
3022017
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression
L Qin, L Liao, A Redmond, L Young, Y Yuan, H Chen, BW O'Malley, J Xu
Molecular and cellular biology 28 (19), 5937-5950, 2008
2242008
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer
E Myers, ADK Hill, G Kelly, EW McDermott, NJ O'Higgins, Y Buggy, ...
Clinical Cancer Research 11 (6), 2111-2122, 2005
1722005
Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1
FJ Fleming, E Myers, G Kelly, TB Crotty, EW McDermott, NJ O’higgins, ...
Journal of clinical pathology 57 (10), 1069-1074, 2004
1682004
Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.
LAV Priedigkeit N, Hartmaier RJ, Chen Y, Vareslija D, Basudan A, Watters RJ ...
JAMA Oncology 3 (5), 666-671, 2017
1602017
Inverse relationship between ER-β and SRC-1 predicts outcome in endocrine-resistant breast cancer
E Myers, FJ Fleming, TB Crotty, G Kelly, EW McDermott, NJ O'higgins, ...
British journal of cancer 91 (9), 1687-1693, 2004
1532004
Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen …
FJ Fleming, ADK Hill, EW McDermott, NJ O’Higgins, LS Young
The Journal of Clinical Endocrinology & Metabolism 89 (1), 375-383, 2004
1272004
The function of steroid receptor coactivator-1 in normal tissues and cancer
CA Walsh, L Qin, JCY Tien, LS Young, J Xu
International journal of biological sciences 8 (4), 470, 2012
1192012
CD44 increases the efficiency of distant metastasis of breast cancer
S McFarlane, JA Coulter, P Tibbits, A O'Grady, C McFarlane, ...
Oncotarget 6 (13), 11465, 2015
1172015
Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer.
OS Pathiraja TN1, Nayak SR, Xi Y, Jiang S, Garee JP, Edwards DP, Lee AV ...
Science Translational Medicine. 6 (229), 229ra41, 2014
1152014
Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence
AM Redmond, FT Bane, AT Stafford, M McIlroy, MF Dillon, TB Crotty, ...
Clinical Cancer Research 15 (6), 2098-2106, 2009
1152009
Transcriptome characterization of matched primary breast and brain metastatic tumors to detect novel actionable targets
D Varešlija, N Priedigkeit, A Fagan, S Purcell, N Cosgrove, PJ O’Halloran, ...
JNCI: Journal of the National Cancer Institute 111 (4), 388-398, 2019
942019
Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation
R Varadarajan, L Golden-Mason, L Young, P McLoughlin, N Nolan, ...
Transplantation 78 (2), 250-256, 2004
922004
Growth factor-dependent regulation of survivin by c-myc in human breast cancer
N Cosgrave, ADK Hill, LS Young
Journal of molecular endocrinology 37 (3), 377-390, 2006
902006
Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow
NJ Hegarty, LS Young, CN Kirwan, AJ O'Neill, DM Bouchier-Hayes, ...
Kidney international 59 (3), 1059-1065, 2001
882001
Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1
J McBryan, SM Theissen, C Byrne, E Hughes, S Cocchiglia, S Sande, ...
Cancer research 72 (2), 548-559, 2012
832012
Review of effects of water pollution on the breeding success of waterbirds, with particular reference to ardeids in Hong Kong
SB De Luca-Abbott, BSF Wong, DB Peakall, PKS Lam, L Young, ...
Ecotoxicology 10, 327-349, 2001
782001
Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer
M McIlroy, D McCartan, S Early, PO Gaora, S Pennington, ADK Hill, ...
Cancer research 70 (4), 1585-1594, 2010
762010
Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer
D Al-Azawi, M Mc Ilroy, G Kelly, AM Redmond, FT Bane, S Cocchiglia, ...
Oncogene 27 (21), 3021-3031, 2008
762008
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