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M. Tyler Guinn
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Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression
Y Li, R Moore, M Guinn, L Bleris
Scientific reports 2 (1), 897, 2012
1132012
Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition
JGT Zańudo, MT Guinn, K Farquhar, M Szenk, SN Steinway, G Balázsi, ...
Physical biology 16 (3), 031002, 2019
482019
Noise-reducing optogenetic negative-feedback gene circuits in human cells
MT Guinn, G Balázsi
Nucleic acids research 47 (14), 7703-7714, 2019
362019
Observation and control of gene expression noise: barrier crossing analogies between drug resistance and metastasis
MT Guinn, Y Wan, S Levovitz, D Yang, MR Rosner, G Balázsi
Frontiers in Genetics 11, 586726, 2020
242020
Biological 2-input decoder circuit in human cells
M Guinn, L Bleris
ACS synthetic biology 3 (8), 627-633, 2014
182014
Reconfigurable hybrid interface for molecular marker diagnostics and in-situ reporting
K Ehrhardt, MT Guinn, T Quarton, MQ Zhang, L Bleris
Biosensors and Bioelectronics 74, 744-750, 2015
112015
Intragraft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics
MT Guinn, ES Szuter, T Yokose, J Ge, IA Rosales, K Chetal, RI Sadreyev, ...
American Journal of Transplantation 23 (9), 1319-1330, 2023
62023
Reliably engineering and controlling stable optogenetic gene circuits in mammalian cells
MT Guinn, D Coraci, L Guinn, G Balázsi
JoVE (Journal of Visualized Experiments), e62109, 2021
22021
Infiltrating CD8+ Cytotoxic T Cells Are Converted to a Regulatory Phenotype in Accepted Kidney Allografts.
T Yokose, ES Szuter, MT Guinn, J Ge, I Rosales, M Ford, PS Russell, ...
AMERICAN JOURNAL OF TRANSPLANTATION 22, 890-890, 2022
12022
Synthetic Gene Circuits for Antimicrobial Resistance and Cancer Research
KS Farquhar, MT Guinn, G Balázsi, DA Charlebois
Synthetic Genomics-From BioBricks to Synthetic Genomes, 2021
12021
Engineering human cells with synthetic gene circuits elucidates how protein levels generate phenotypic landscapes
MT Guinn
State University of New York at Stony Brook, 2020
12020
Dysfunction of infiltrating cytotoxic CD8+ T cells within the graft promotes murine kidney allotransplant tolerance
T Yokose, ES Szuter, I Rosales, MT Guinn, AS Liss, T Baba, DA Ruddy, ...
The Journal of Clinical Investigation, 2024
2024
Commentary: The power of a patch: Utilizing exosome therapy to treat heart disease
MT Guinn, TK Rosengart
The Journal of Thoracic and Cardiovascular Surgery 166 (6), e533-e534, 2023
2023
Development of an M2 Macrophage Signature in Spontaneously Accepted Kidney Allografts.
MT Guinn, ES Szuter, T Yokose, J Ge, B Kwon, I Rosales, PS Russell, ...
AMERICAN JOURNAL OF TRANSPLANTATION 22, 886-886, 2022
2022
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft.
ES Szuter, T Yokose, MT Guinn, J Ge, I Rosales, B Kwon, PS Russell, ...
AMERICAN JOURNAL OF TRANSPLANTATION 22, 593-593, 2022
2022
Trajectory Analysis of Single Cell RNAseq Data Suggest Intrarenal Induction of Tregs in Spontaneously Accepted Kidney Allografts
M Guinn, ES Szuter, T Yokose, J Ge, B Kwon, I Rosales, PS Russell, ...
AMERICAN JOURNAL OF TRANSPLANTATION 22, 604-604, 2022
2022
Synthetic Gene Circuits Reveal how KRAS(G12V) Affects Cell Proliferation & Migration Patterns
T Guinn, G Coraci, Damiano, Balazsi
APS Meeting Abstracts, 2020
2020
Book Review: Quantitative Biology: Theory, Computational Methods, and Models. Edited by Brian Munsky, William S. Hlavacek, and Lev S. Tsimring. Cambridge (Massachusetts): MIT …
MT Guinn, G Balazsi
The Quarterly Review of Biology 94 (4), 425-426, 2019
2019
Mammalian Gene Expression Control & Noise Reduction using Optogenetic Negative Feedback Circuits
MT Guinn, G Balazsi
qBio 2019 Conference, 2019
2019
Noise-Reducing Optogenetic Circuits in Mammalian Cells
MT Guinn, G Balazsi
2019 Synthetic Biology: Engineering, Evolution & Design (SEED), 2019
2019
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