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Constantinos Zambirinis
Constantinos Zambirinis
Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey
E-mail confirmado em rutgers.edu
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The pancreatic cancer microbiome promotes oncogenesis by induction of innate and adaptive immune suppression
S Pushalkar, M Hundeyin, D Daley, CP Zambirinis, E Kurz, A Mishra, ...
Cancer discovery 8 (4), 403-416, 2018
984*2018
Extracellular vesicle and particle biomarkers define multiple human cancers
A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ...
Cell 182 (4), 1044-1061. e18, 2020
8152020
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL
B Aykut, S Pushalkar, R Chen, Q Li, R Abengozar, JI Kim, SA Shadaloey, ...
Nature 574 (7777), 264-267, 2019
5952019
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
L Seifert, G Werba, S Tiwari, NN Giao Ly, S Alothman, D Alqunaibit, ...
Nature 532 (7598), 245-249, 2016
5252016
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
A Ochi, AH Nguyen, AS Bedrosian, HM Mushlin, S Zarbakhsh, R Barilla, ...
The Journal of Experimental Medicine 209 (9), 1671-1687, 2012
3222012
γδ T cells support pancreatic oncogenesis by restraining αβ T cell activation
D Daley, CP Zambirinis, L Seifert, N Akkad, N Mohan, G Werba, R Barilla, ...
Cell 166 (6), 1485-1499. e15, 2016
3042016
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
D Daley, VR Mani, N Mohan, N Akkad, A Ochi, DW Heindel, KB Lee, ...
Nature medicine 23 (5), 556-567, 2017
2962017
Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans
A Ochi, CS Graffeo, CP Zambirinis, A Rehman, M Hackman, N Fallon, ...
The Journal of clinical investigation 122 (11), 4118-4129, 2012
2172012
Pancreatic cancer, inflammation, and microbiome
CP Zambirinis, S Pushalkar, D Saxena, G Miller
The Cancer Journal 20 (3), 195-202, 2014
1932014
Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice
JR Henning, CS Graffeo, A Rehman, NC Fallon, CP Zambirinis, A Ochi, ...
Hepatology 58 (2), 589-602, 2013
1812013
Dendritic Cell Populations with Different Concentrations of Lipid Regulate Tolerance and Immunity in Mouse and Human Liver
J Ibrahim, AH Nguyen, A Rehman, A Ochi, M Jamal, CS Graffeo, ...
Gastroenterology, 2012
1702012
TLR9 ligation in pancreatic stellate cells promotes tumorigenesis
CP Zambirinis, E Levie, S Nguy, A Avanzi, R Barilla, Y Xu, L Seifert, ...
Journal of Experimental Medicine 212 (12), 2077-2094, 2015
1602015
Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury
M Deutsch, CS Graffeo, R Rokosh, M Pansari, A Ochi, EM Levie, ...
Cell death & disease 6 (5), e1759-e1759, 2015
1302015
Role of fatty-acid synthesis in dendritic cell generation and function
A Rehman, KC Hemmert, A Ochi, M Jamal, JR Henning, R Barilla, ...
The Journal of Immunology 190 (9), 4640-4649, 2013
1062013
Dectin-1 regulates hepatic fibrosis and hepatocarcinogenesis by suppressing TLR4 signaling pathways
L Seifert, M Deutsch, S Alothman, D Alqunaibit, G Werba, M Pansari, ...
Cell reports 13 (9), 1909-1921, 2015
902015
Interleukin 17–producing γδT cells promote hepatic regeneration in Mice
R Rao, CS Graffeo, R Gulati, M Jamal, S Narayan, CP Zambirinis, ...
Gastroenterology 147 (2), 473-484. e2, 2014
792014
TGF-β blockade reduces mortality and metabolic changes in a validated murine model of pancreatic cancer cachexia
SH Greco, L Tomkötter, AK Vahle, R Rokosh, A Avanzi, SK Mahmood, ...
PloS one 10 (7), e0132786, 2015
742015
P53 and EGFR expression in colorectal cancer: a reappraisal of ‘old’tissue markers in patients with long follow-up
GE Theodoropoulos, E Karafoka, JG Papailiou, P Stamopoulos, ...
Anticancer research 29 (2), 785-791, 2009
732009
Adoptive immunotherapy of epithelial ovarian cancer with Vγ9Vδ2 T cells, potentiated by liposomal alendronic acid
AC Parente-Pereira, H Shmeeda, LM Whilding, CP Zambirinis, J Foster, ...
The Journal of Immunology 193 (11), 5557-5566, 2014
642014
Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer
J Zheng, JM Hernandez, A Doussot, L Bojmar, CP Zambirinis, ...
Hpb 20 (7), 597-604, 2018
552018
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