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Christopher M. Rath
Christopher M. Rath
Totus Medicines
E-mail confirmado em totusmedicines.com - Página inicial
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Molecular networking as a dereplication strategy
JY Yang, LM Sanchez, CM Rath, X Liu, PD Boudreau, N Bruns, E Glukhov, ...
Journal of natural products 76 (9), 1686-1699, 2013
6502013
Molecular cartography of the human skin surface in 3D
A Bouslimani, C Porto, CM Rath, M Wang, Y Guo, A Gonzalez, ...
Proceedings of the National Academy of Sciences 112 (17), E2120-E2129, 2015
3892015
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743
CM Rath, B Janto, J Earl, A Ahmed, FZ Hu, L Hiller, M Dahlgren, R Kreft, ...
ACS chemical biology 6 (11), 1244-1256, 2011
2412011
Structures and Cytotoxic Properties of Trichoverroids and Their Macrolide Analogues Produced by Saltwater Culture of Myrothecium verrucaria
T Amagata, C Rath, JF Rigot, N Tarlov, K Tenney, FA Valeriote, P Crews
Journal of Medicinal Chemistry 46 (20), 4342-4350, 2003
952003
Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations
CM Rath, T Alexandrov, SK Higginbottom, J Song, ME Milla, ...
Analytical chemistry 84 (21), 9259-9267, 2012
872012
In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont
NB Lopanik, JA Shields, TJ Buchholz, CM Rath, J Hothersall, ...
Chemistry & biology 15 (11), 1175-1186, 2008
862008
Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin
DA Hansen, CM Rath, EB Eisman, ARH Narayan, JD Kittendorf, ...
Journal of the American Chemical Society 135 (30), 11232-11238, 2013
762013
Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid …
J Bojkovic, DL Richie, DA Six, CM Rath, WS Sawyer, Q Hu, CR Dean
Journal of bacteriology 198 (4), 731-741, 2016
752016
The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes
CM Rath, PC Dorrestein
Current opinion in microbiology 15 (2), 147-154, 2012
752012
Structural and functional analysis of AsbF: origin of the stealth 3, 4-dihydroxybenzoic acid subunit for petrobactin biosynthesis
BF Pfleger, Y Kim, TD Nusca, N Maltseva, JY Lee, CM Rath, JB Scaglione, ...
Proceedings of the National Academy of Sciences 105 (44), 17133-17138, 2008
752008
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor
JA Chemler, TJ Buchholz, TW Geders, DL Akey, CM Rath, GE Chlipala, ...
Journal of the American Chemical Society 134 (17), 7359-7366, 2012
722012
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase
JB Scaglione, DL Akey, R Sullivan, JD Kittendorf, CM Rath, ES Kim, ...
Angewandte Chemie (International ed. in English) 49 (33), 5726, 2010
672010
Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module
Y Ding, CM Rath, KL Bolduc, K Håkansson, DH Sherman
Journal of the American Chemical Society 133 (37), 14492-14495, 2011
532011
Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase
TJ Buchholz, CM Rath, NB Lopanik, NP Gardner, K Håkansson, ...
Chemistry & biology 17 (10), 1092-1100, 2010
472010
Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate
ME Rateb, Y Zhai, E Ehrner, CM Rath, X Wang, J Tabudravu, R Ebel, ...
Organic & Biomolecular Chemistry 13 (37), 9585-9592, 2015
462015
Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism
D Dovala, CM Rath, Q Hu, WS Sawyer, S Shia, RA Elling, MS Knapp, ...
Proceedings of the National Academy of Sciences 113 (41), E6064-E6071, 2016
442016
Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS
SA Bonnett, CM Rath, AR Shareef, JR Joels, JA Chemler, K Håkansson, ...
Chemistry & biology 18 (9), 1075-1081, 2011
372011
Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606
CRD Daryl L. Richie, Kenneth T. Takeoka, Jade Bojkovic, Louis E. Metzger IV ...
PLOSone 11 (8), e0160918, 2016
32*2016
Rapid analysis of protein expression and solubility with the SpyTag–SpyCatcher system
Dustin Dovala, William S. Sawyer, Christopher M. Rath, Louis E. Metzger IV
Protein Expression and Purification, 2015
28*2015
Discovery and optimization of phosphopantetheine adenylyltransferase inhibitors with gram-negative antibacterial activity
CK Skepper, RJ Moreau, BA Appleton, BM Benton, JE Drumm III, BY Feng, ...
Journal of Medicinal Chemistry 61 (8), 3325-3349, 2018
272018
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