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Darren M Riddy
Darren M Riddy
E-mail confirmado em monash.edu
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G protein–coupled receptors targeting insulin resistance, obesity, and type 2 diabetes mellitus
DM Riddy, P Delerive, RJ Summers, PM Sexton, CJ Langmead
Pharmacological reviews 70 (1), 39-67, 2018
1212018
New advances in targeting the resolution of inflammation: implications for specialized pro-resolving mediator GPCR drug discovery
J Park, CJ Langmead, DM Riddy
ACS pharmacology & translational science 3 (1), 88-106, 2020
892020
Fevipiprant (QAW039), a slowly dissociating CRTh2 antagonist with the potential for improved clinical efficacy
DA Sykes, ME Bradley, DM Riddy, E Willard, J Reilly, A Miah, C Bauer, ...
Molecular pharmacology 89 (5), 593-605, 2016
732016
Fevipiprant (QAW039), a slowly dissociating CRTh2 antagonist with the potential for improved clinical efficacy
DA Sykes, ME Bradley, DM Riddy, E Willard, J Reilly, A Miah, C Bauer, ...
Molecular pharmacology 89 (5), 593-605, 2016
732016
Investigating the molecular mechanisms through which FTY720‐P causes persistent S1P1 receptor internalization
DA Sykes, DM Riddy, C Stamp, ME Bradley, N McGuiness, A Sattikar, ...
British journal of pharmacology 171 (21), 4797-4807, 2014
582014
Isoform-specific biased agonism of histamine H3 receptor agonists
DM Riddy, AE Cook, NA Diepenhorst, S Bosnyak, R Brady, CM La Cour, ...
Molecular Pharmacology 91 (2), 87-99, 2017
46*2017
Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research
DM Riddy, E Goy, P Delerive, RJ Summers, PM Sexton, CJ Langmead
PloS one 13 (5), e0197177, 2018
412018
A prospective study of isolated human hepatocyte function following liver resection for colorectal liver metastases: the effects of prior exposure to chemotherapy
JC Hewes, D Riddy, RW Morris, AJ Woodrooffe, BR Davidson, B Fuller
Journal of hepatology 45 (2), 263-270, 2006
352006
Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma
DA Sandham, L Barker, L Brown, Z Brown, D Budd, SJ Charlton, ...
ACS Medicinal Chemistry Letters 8 (5), 582-586, 2017
332017
Acetylcholine muscarinic M4 receptors as a therapeutic target for alcohol use disorder: converging evidence from humans and rodents
LC Walker, AE Berizzi, NA Chen, P Rueda, VM Perreau, K Huckstep, ...
Biological Psychiatry 88 (12), 898-909, 2020
312020
Label-free kinetics: exploiting functional hemi-equilibrium to derive rate constants for muscarinic receptor antagonists
DM Riddy, C Valant, P Rueda, WN Charman, PM Sexton, RJ Summers, ...
Molecular pharmacology 88 (4), 779-790, 2015
202015
Reassessment of the pharmacology of Sphingosine‐1‐phosphate S1P3 receptor ligands using the DiscoveRx PathHunter™ and Ca2+ release functional assays
DM Riddy, C Stamp, DA Sykes, SJ Charlton, MR Dowling
British journal of pharmacology 167 (4), 868-880, 2012
152012
Multipathway In vitro pharmacological characterization of specialized proresolving G protein-coupled receptors
J Merlin, J Park, TH Vandekolk, SA Fabb, J Allinne, RJ Summers, ...
Molecular Pharmacology 101 (4), 246-256, 2022
92022
Mannoury la Cour C., Mocaer E., Summers RJ, Charman WN, Sexton PM, Christopoulos A., Langmead CJ, 2016. Isoform-specific biased agonism of histamine H3 receptor agonists
DM Riddy, AE Cook, NA Diepenhorst, S Bosnyak, R Brady
Mol Pharmacol 91 (2), 87-99, 0
6
Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms
DM Riddy, HL Kammoun, AJ Murphy, S Bosnyak-Gladovic, ...
BMJ Open Diabetes Research and Care 9 (2), e002285, 2021
52021
Mannoury la Cour C., Sors A., Charman WN, Summers RJ, Sexton PM, et al. Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 …
DM Riddy, AE Cook, DM Shackleford, TL Pierce, E Mocaer
Neuropharmacology 144, 244-255, 2019
42019
Effect of alosetron and tegaserod at the 5-HT2B receptor in human colon
RA Borman, J Wade, J Root, D Riddy, K Clark, B Coleman
Gastroenterology 128 (4), A271-A271, 2005
32005
Pharmacology of S1P3 ligands using the DiscoverRx PathHunterTM and Ca2+ release functional assays: Re-assessment of the pharmacology of VPC24191 and VPC23019.
D Riddy, C Stamp, D Sykes, S Charlton, M Dowling
British Journal of Pharmacology, 2012
12012
Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates
MK Rinne, L Urvas, I Mandrika, D Fridmanis, DM Riddy, CJ Langmead, ...
Scientific Reports 14 (1), 7690, 2024
2024
MUSCARINIC ACETYLCHOLINE RECEPTORS IN ALCOHOL USE DISORDER
LC Walker, AE Berrizi, NA Chen, P Rueda, VM Perreau, K Huckstep, ...
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 44, 37-37, 2020
2020
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