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Iris Romero
Iris Romero
University of Chciago
E-mail confirmado em babies.bsd.uchicago.edu
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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ...
Nature medicine 17 (11), 1498-1503, 2011
21972011
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ...
Nature reviews Cancer 15 (11), 668-679, 2015
11402015
Adipose tissue and adipocytes support tumorigenesis and metastasis
KM Nieman, IL Romero, B Van Houten, E Lengyel
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013
8252013
CD95 promotes tumour growth
L Chen, SM Park, AV Tumanov, A Hau, K Sawada, C Feig, JR Turner, ...
Nature 465 (7297), 492-496, 2010
4582010
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
HA Kenny, CY Chiang, EA White, EM Schryver, M Habis, IL Romero, ...
The Journal of clinical investigation 124 (10), 4614-4628, 2014
3112014
Metformin targets central carbon metabolism and reveals mitochondrial requirements in human cancers
X Liu, IL Romero, LM Litchfield, E Lengyel, JW Locasale
Cell metabolism 24 (5), 728-739, 2016
2292016
Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity
IL Romero, A McCormick, KA McEwen, SY Park, T Karrison, SD Yamada, ...
Obstetrics & Gynecology 119 (1), 61-67, 2012
2022012
Adipocyte-induced FABP4 expression in ovarian cancer cells promotes metastasis and mediates carboplatin resistance
A Mukherjee, CY Chiang, HA Daifotis, KM Nieman, JF Fahrmann, ...
Cancer research 80 (8), 1748-1761, 2020
1622020
Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis
M Zillhardt, SM Park, IL Romero, K Sawada, A Montag, T Krausz, ...
Clinical Cancer Research 17 (12), 4042-4051, 2011
1472011
Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models
E Lengyel, LM Litchfield, AK Mitra, KM Nieman, A Mukherjee, Y Zhang, ...
American journal of obstetrics and gynecology 212 (4), 479. e1-479. e10, 2015
1432015
A pan-ALDH1A inhibitor induces necroptosis in ovarian cancer stem-like cells
I Chefetz, E Grimley, K Yang, L Hong, EV Vinogradova, R Suciu, ...
Cell reports 26 (11), 3061-3075. e6, 2019
1182019
Molecular pathways: trafficking of metabolic resources in the tumor microenvironment
IL Romero, A Mukherjee, HA Kenny, LM Litchfield, E Lengyel
Clinical Cancer Research 21 (4), 680-686, 2015
952015
Old drug, new trick: repurposing metformin for gynecologic cancers?
T Febbraro, E Lengyel, IL Romero
Gynecologic oncology 135 (3), 614-621, 2014
882014
SPHK1 is a novel target of metformin in ovarian cancer
PC Hart, T Chiyoda, X Liu, M Weigert, M Curtis, CY Chiang, R Loth, ...
Molecular Cancer Research 17 (4), 870-881, 2019
622019
Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers
RSC Guindalini, Y Zheng, H Abe, K Whitaker, TF Yoshimatsu, T Walsh, ...
Clinical Cancer Research 25 (6), 1786-1794, 2019
592019
Association of metformin use with outcomes in advanced endometrial cancer treated with chemotherapy
O Ezewuiro, TA Grushko, M Kocherginsky, M Habis, JA Hurteau, KA Mills, ...
PloS one 11 (1), e0147145, 2016
572016
Statin therapy is associated with improved survival in patients with non-serous-papillary epithelial ovarian cancer: a retrospective cohort analysis
M Habis, K Wroblewski, M Bradaric, N Ismail, SD Yamada, L Litchfield, ...
PloS one 9 (8), e104521, 2014
552014
MAGENTA (Making Genetic testing accessible): a prospective randomized controlled trial comparing online genetic education and telephone genetic counseling for hereditary cancer …
N Rayes, DJ Bowen, T Coffin, D Nebgen, C Peterson, MF Munsell, ...
BMC cancer 19, 1-8, 2019
412019
Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer
LM Litchfield, A Mukherjee, MA Eckert, A Johnson, KA Mills, S Pan, ...
Oncotarget 6 (27), 23548, 2015
412015
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk
PC Hart, HA Kenny, N Grassl, KM Watters, LM Litchfield, F Coscia, ...
Cell reports 29 (12), 4086-4098. e6, 2019
312019
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