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Photini Sinnis
Photini Sinnis
Johns Hopkins School of Public Health
E-mail confirmado em jhu.edu - Página inicial
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Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes.
U Frevert, P Sinnis, C Cerami, W Shreffler, B Takacs, V Nussenzweig
The Journal of experimental medicine 177 (5), 1287-1298, 1993
4631993
The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites
C Cerami, U Frevert, P Sinnis, B Takacs, P Clavijo, MJ Santos, ...
Cell 70 (6), 1021-1033, 1992
4581992
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
A Coppi, R Natarajan, G Pradel, BL Bennett, ER James, MA Roggero, ...
Journal of Experimental Medicine 208 (2), 341-356, 2011
3862011
Plasmodium sporozoites trickle out of the injection site
LM Yamauchi, A Coppi, G Snounou, P Sinnis
Cellular microbiology 9 (5), 1215-1222, 2007
3742007
Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells
A Coppi, R Tewari, JR Bishop, BL Bennett, R Lawrence, JD Esko, ...
Cell host & microbe 2 (5), 316-327, 2007
3592007
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ...
Cell host & microbe 4 (6), 567-578, 2008
3382008
Quantitative Dynamics of Plasmodium yoelii Sporozoite Transmission by Infected Anopheline Mosquitoes
DL Medica, P Sinnis
Infection and immunity 73 (7), 4363-4369, 2005
2762005
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
NK Kisalu, AH Idris, C Weidle, Y Flores-Garcia, BJ Flynn, BK Sack, ...
Nature medicine 24 (4), 408-416, 2018
2732018
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion
A Coppi, C Pinzon-Ortiz, C Hutter, P Sinnis
The Journal of experimental medicine 201 (1), 27-33, 2005
2672005
Malaria in India: the center for the study of complex malaria in India
A Das, AR Anvikar, LJ Cator, RC Dhiman, A Eapen, N Mishra, BN Nagpal, ...
Acta tropica 121 (3), 267-273, 2012
2162012
Proteasome Inhibitors Block Development ofPlasmodium spp
SM Gantt, JM Myung, MRS Briones, WD Li, EJ Corey, S Omura, ...
Antimicrobial agents and chemotherapy 42 (10), 2731-2738, 1998
2151998
Antimalarial activity of allicin, a biologically active compound from garlic cloves
A Coppi, M Cabinian, D Mirelman, P Sinnis
Antimicrobial Agents and chemotherapy 50 (5), 1731-1737, 2006
2112006
Total and putative surface proteomics of malaria parasite salivary gland sporozoites
SE Lindner, KE Swearingen, A Harupa, AM Vaughan, P Sinnis, RL Moritz, ...
Molecular & cellular proteomics 12 (5), 1127-1143, 2013
2002013
Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass …
KE Swearingen, SE Lindner, L Shi, MJ Shears, A Harupa, CS Hopp, ...
PLoS pathogens 12 (4), e1005606, 2016
1902016
The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites
JM Myung, P Marshall, P Sinnis
Molecular and biochemical parasitology 133 (1), 53-59, 2004
1862004
The Binding of the Circumsporozoite Protein to Cell Surface Heparan Sulfate Proteoglycans Is Required for PlasmodiumSporozoite Attachment to Target Cells
C Pinzon-Ortiz, J Friedman, J Esko, P Sinnis
Journal of Biological Chemistry 276 (29), 26784-26791, 2001
1802001
Structural and functional properties of region II-plus of the malaria circumsporozoite protein.
P Sinnis, P Clavijo, D Fenyö, BT Chait, C Cerami, V Nussenzweig
The Journal of experimental medicine 180 (1), 297-306, 1994
1721994
Plasmodium sporozoite–host interactions from the dermis to the hepatocyte
I Ejigiri, P Sinnis
Current opinion in microbiology 12 (4), 401-407, 2009
1592009
Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition
CS Hopp, K Chiou, DRT Ragheb, AM Salman, SM Khan, AJ Liu, P Sinnis
Elife 4, e07789, 2015
1452015
Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity
I Ejigiri, DRT Ragheb, P Pino, A Coppi, BL Bennett, D Soldati-Favre, ...
PLoS pathogens 8 (7), e1002725, 2012
1362012
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