Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. U Frevert, P Sinnis, C Cerami, W Shreffler, B Takacs, V Nussenzweig The Journal of experimental medicine 177 (5), 1287-1298, 1993 | 463 | 1993 |
The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites C Cerami, U Frevert, P Sinnis, B Takacs, P Clavijo, MJ Santos, ... Cell 70 (6), 1021-1033, 1992 | 458 | 1992 |
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host A Coppi, R Natarajan, G Pradel, BL Bennett, ER James, MA Roggero, ... Journal of Experimental Medicine 208 (2), 341-356, 2011 | 386 | 2011 |
Plasmodium sporozoites trickle out of the injection site LM Yamauchi, A Coppi, G Snounou, P Sinnis Cellular microbiology 9 (5), 1215-1222, 2007 | 374 | 2007 |
Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells A Coppi, R Tewari, JR Bishop, BL Bennett, R Lawrence, JD Esko, ... Cell host & microbe 2 (5), 316-327, 2007 | 359 | 2007 |
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ... Cell host & microbe 4 (6), 567-578, 2008 | 338 | 2008 |
Quantitative Dynamics of Plasmodium yoelii Sporozoite Transmission by Infected Anopheline Mosquitoes DL Medica, P Sinnis Infection and immunity 73 (7), 4363-4369, 2005 | 276 | 2005 |
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite NK Kisalu, AH Idris, C Weidle, Y Flores-Garcia, BJ Flynn, BK Sack, ... Nature medicine 24 (4), 408-416, 2018 | 273 | 2018 |
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion A Coppi, C Pinzon-Ortiz, C Hutter, P Sinnis The Journal of experimental medicine 201 (1), 27-33, 2005 | 267 | 2005 |
Malaria in India: the center for the study of complex malaria in India A Das, AR Anvikar, LJ Cator, RC Dhiman, A Eapen, N Mishra, BN Nagpal, ... Acta tropica 121 (3), 267-273, 2012 | 216 | 2012 |
Proteasome Inhibitors Block Development ofPlasmodium spp SM Gantt, JM Myung, MRS Briones, WD Li, EJ Corey, S Omura, ... Antimicrobial agents and chemotherapy 42 (10), 2731-2738, 1998 | 215 | 1998 |
Antimalarial activity of allicin, a biologically active compound from garlic cloves A Coppi, M Cabinian, D Mirelman, P Sinnis Antimicrobial Agents and chemotherapy 50 (5), 1731-1737, 2006 | 211 | 2006 |
Total and putative surface proteomics of malaria parasite salivary gland sporozoites SE Lindner, KE Swearingen, A Harupa, AM Vaughan, P Sinnis, RL Moritz, ... Molecular & cellular proteomics 12 (5), 1127-1143, 2013 | 200 | 2013 |
Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass … KE Swearingen, SE Lindner, L Shi, MJ Shears, A Harupa, CS Hopp, ... PLoS pathogens 12 (4), e1005606, 2016 | 190 | 2016 |
The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites JM Myung, P Marshall, P Sinnis Molecular and biochemical parasitology 133 (1), 53-59, 2004 | 186 | 2004 |
The Binding of the Circumsporozoite Protein to Cell Surface Heparan Sulfate Proteoglycans Is Required for PlasmodiumSporozoite Attachment to Target Cells C Pinzon-Ortiz, J Friedman, J Esko, P Sinnis Journal of Biological Chemistry 276 (29), 26784-26791, 2001 | 180 | 2001 |
Structural and functional properties of region II-plus of the malaria circumsporozoite protein. P Sinnis, P Clavijo, D Fenyö, BT Chait, C Cerami, V Nussenzweig The Journal of experimental medicine 180 (1), 297-306, 1994 | 172 | 1994 |
Plasmodium sporozoite–host interactions from the dermis to the hepatocyte I Ejigiri, P Sinnis Current opinion in microbiology 12 (4), 401-407, 2009 | 159 | 2009 |
Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition CS Hopp, K Chiou, DRT Ragheb, AM Salman, SM Khan, AJ Liu, P Sinnis Elife 4, e07789, 2015 | 145 | 2015 |
Shedding of TRAP by a rhomboid protease from the malaria sporozoite surface is essential for gliding motility and sporozoite infectivity I Ejigiri, DRT Ragheb, P Pino, A Coppi, BL Bennett, D Soldati-Favre, ... PLoS pathogens 8 (7), e1002725, 2012 | 136 | 2012 |