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Janet Lord
Janet Lord
Professor of Immune Cell Biology, University of Birmingham, UK
E-mail confirmado em bham.ac.uk - Página inicial
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Serine/threonine protein kinases and apoptosis
TG Cross, D Scheel-Toellner, NV Henriquez, E Deacon, M Salmon, ...
Experimental cell research 256 (1), 34-41, 2000
8582000
Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation
CD Buckley, D Pilling, JM Lord, AN Akbar, D Scheel-Toellner, M Salmon
Trends in immunology 22 (4), 199-204, 2001
6612001
Aging of the innate immune system
AC Shaw, S Joshi, H Greenwood, A Panda, JM Lord
Current opinion in immunology 22 (4), 507-513, 2010
6412010
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
K Raza, F Falciani, SJ Curnow, EJ Ross, CY Lee, AN Akbar, JM Lord, ...
Arthritis research & therapy 7 (4), 1-12, 2005
5942005
RGD peptides induce apoptosis by direct caspase-3 activation
CD Buckley, D Pilling, NV Henriquez, G Parsonage, K Threlfall, ...
Nature 397 (6719), 534-539, 1999
5681999
The systemic immune response to trauma: an overview of pathophysiology and treatment
JM Lord, MJ Midwinter, YF Chen, A Belli, K Brohi, EJ Kovacs, ...
The Lancet 384 (9952), 1455-1465, 2014
5212014
Human innate immunosenescence: causes and consequences for immunity in old age
A Panda, A Arjona, E Sapey, F Bai, E Fikrig, RR Montgomery, JM Lord, ...
Trends in immunology 30 (7), 325-333, 2009
4922009
Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans
SK Butcher, H Chahal, L Nayak, A Sinclair, NV Henriquez, E Sapey, ...
Journal of leukocyte biology 70 (6), 881-886, 2001
4222001
Persistent induction of the chemokine receptor CXCR4 by TGF-β1 on synovial T cells contributes to their accumulation within the rheumatoid synovium
CD Buckley, N Amft, PF Bradfield, D Pilling, E Ross, ...
The Journal of Immunology 165 (6), 3423-3429, 2000
3902000
Frailty and sarcopenia: the potential role of an aged immune system
D Wilson, T Jackson, E Sapey, JM Lord
Ageing research reviews 36, 1-10, 2017
3502017
Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence
E Sapey, H Greenwood, G Walton, E Mann, A Love, N Aaronson, ...
Blood, The Journal of the American Society of Hematology 123 (2), 239-248, 2014
2872014
PKC-δ is an apoptotic lamin kinase
T Cross, G Griffiths, E Deacon, R Sallis, M Gough, D Watters, JM Lord
Oncogene 19 (19), 2331-2337, 2000
2782000
Spontaneous neutrophil apoptosis involves caspase 3-mediated activation of protein kinase C-δ
J Pongracz, P Webb, K Wang, E Deacon, OJ Lunn, JM Lord
Journal of Biological Chemistry 274 (52), 37329-37334, 1999
2351999
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals
J Hazeldine, P Harris, IL Chapple, M Grant, H Greenwood, A Livesey, ...
Aging cell 13 (4), 690-698, 2014
2292014
Diacylglycerol and phosphatidate generated by phospholipases C and D, respectively, have distinct fatty acid compositions and functions: phospholipase D-derived diacylglycerol …
TR Pettitt, A Martin, T Horton, C Liossis, JM Lord, MJO Wakelam
Journal of Biological Chemistry 272 (28), 17354-17359, 1997
2261997
The impact of ageing on natural killer cell function and potential consequences for health in older adults
J Hazeldine, JM Lord
Ageing research reviews 12 (4), 1069-1078, 2013
2242013
Neutrophil ageing and immunesenescence
JM Lord, S Butcher, V Killampali, D Lascelles, M Salmon
Mechanisms of ageing and development 122 (14), 1521-1535, 2001
2202001
Reactive oxygen species limit neutrophil life span by activating death receptor signaling
D Scheel-Toellner, K Wang, R Craddock, PR Webb, HM McGettrick, ...
Blood 104 (8), 2557-2564, 2004
2152004
Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate
JM Challacombe, A Suhrbier, PG Parsons, B Jones, P Hampson, ...
The Journal of Immunology 177 (11), 8123-8132, 2006
2032006
Immune-endocrine biomarkers as predictors of frailty and mortality: a 10-year longitudinal study in community-dwelling older people
D Baylis, DB Bartlett, HE Syddall, G Ntani, CR Gale, C Cooper, JM Lord, ...
Age 35 (3), 963-971, 2013
2022013
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