A novel community driven software for functional enrichment analysis of extracellular vesicles data M Pathan, S Keerthikumar, D Chisanga, R Alessandro, CS Ang, ... Journal of extracellular vesicles 6 (1), 1321455, 2017 | 342 | 2017 |
Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells C Cossetti, N Iraci, TR Mercer, T Leonardi, E Alpi, D Drago, ... Molecular cell 56 (2), 193-204, 2014 | 330 | 2014 |
Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles N Iraci, T Leonardi, F Gessler, B Vega, S Pluchino International journal of molecular sciences 17 (2), 171, 2016 | 300 | 2016 |
Macrophage-derived extracellular succinate licenses neural stem cells to suppress chronic neuroinflammation L Peruzzotti-Jametti, JD Bernstock, N Vicario, ASH Costa, CK Kwok, ... Cell stem cell 22 (3), 355-368. e13, 2018 | 241 | 2018 |
microRNAs in Parkinson’s disease: from pathogenesis to novel diagnostic and therapeutic approaches L Leggio, S Vivarelli, F L’Episcopo, C Tirolo, S Caniglia, N Testa, ... International journal of molecular sciences 18 (12), 2698, 2017 | 227 | 2017 |
Design and synthesis of diselenobisbenzamides (DISeBAs) as nucleocapsid protein 7 (NCp7) inhibitors with anti-HIV activity L Sancineto, A Mariotti, L Bagnoli, F Marini, J Desantis, N Iraci, C Santi, ... Journal of medicinal chemistry 58 (24), 9601-9614, 2015 | 206 | 2015 |
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis T Liu, AEL Tee, A Porro, SA Smith, T Dwarte, PY Liu, N Iraci, E Sekyere, ... Proceedings of the National Academy of Sciences 104 (47), 18682-18687, 2007 | 145 | 2007 |
Pharmacophore‐based discovery of small‐molecule inhibitors of protein–protein interactions between HIV‐1 integrase and cellular cofactor LEDGF/p75 L De Luca, ML Barreca, S Ferro, F Christ, N Iraci, R Gitto, AM Monforte, ... ChemMedChem 4 (8), 1311-1316, 2009 | 137 | 2009 |
Extracellular vesicles are independent metabolic units with asparaginase activity N Iraci, E Gaude, T Leonardi, ASH Costa, C Cossetti, L Peruzzotti-Jametti, ... Nature chemical biology 13 (9), 951-955, 2017 | 128 | 2017 |
Neural stem cells traffic functional mitochondria via extracellular vesicles L Peruzzotti-Jametti, JD Bernstock, CM Willis, G Manferrari, R Rogall, ... PLoS biology 19 (4), e3001166, 2021 | 114 | 2021 |
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects GM Marshall, S Gherardi, N Xu, Z Neiron, T Trahair, CJ Scarlett, ... Oncogene 29 (44), 5957-5968, 2010 | 112 | 2010 |
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors S Sabatini, F Gosetto, S Serritella, G Manfroni, O Tabarrini, N Iraci, ... Journal of Medicinal Chemistry 55 (7), 3568-3572, 2012 | 100 | 2012 |
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains ML Barreca, A Rao, L De Luca, N Iraci, AM Monforte, G Maga, ... Bioorganic & medicinal chemistry letters 17 (7), 1956-1960, 2007 | 91 | 2007 |
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model IL Shytaj, S Norelli, B Chirullo, A Della Corte, M Collins, J Yalley-Ogunro, ... PLoS pathogens 8 (6), e1002774, 2012 | 85 | 2012 |
Microglia polarization, gene-environment interactions and Wnt/β-catenin signaling: emerging roles of glia-neuron and glia-stem/neuroprogenitor crosstalk for dopaminergic … F L'Episcopo, C Tirolo, MF Serapide, S Caniglia, N Testa, L Leggio, ... Frontiers in aging neuroscience 10, 12, 2018 | 76 | 2018 |
Induced‐fit docking approach provides insight into the binding mode and mechanism of action of HIV‐1 integrase inhibitors ML Barreca, N Iraci, L De Luca, A Chimirri ChemMedChem: Chemistry Enabling Drug Discovery 4 (9), 1446-1456, 2009 | 72 | 2009 |
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors A Astolfi, T Felicetti, N Iraci, G Manfroni, S Massari, D Pietrella, O Tabarrini, ... Journal of medicinal chemistry 60 (4), 1598-1604, 2017 | 66 | 2017 |
Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? A Fuster-Matanzo, F Gessler, T Leonardi, N Iraci, S Pluchino Stem cell research & therapy 6, 1-10, 2015 | 63 | 2015 |
Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases JA Smith, T Leonardi, B Huang, N Iraci, B Vega, S Pluchino Biogerontology 16, 147-185, 2015 | 62 | 2015 |
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors ML Barreca, L De Luca, N Iraci, A Rao, S Ferro, G Maga, A Chimirri Journal of chemical information and modeling 47 (2), 557-562, 2007 | 62 | 2007 |