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J. Crawford Downs
J. Crawford Downs
Professor of Ophthalmology and Visual Sciences, UAB
E-mail confirmado em uab.edu - Página inicial
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The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve …
CF Burgoyne, JC Downs, AJ Bellezza, JKF Suh, RT Hart
Progress in retinal and eye research 24 (1), 39-73, 2005
12682005
Deformation of the lamina cribrosa and anterior scleral canal wall in early experimental glaucoma
AJ Bellezza, CJ Rintalan, HW Thompson, JC Downs, RT Hart, ...
Investigative ophthalmology & visual science 44 (2), 623-637, 2003
4702003
Mechanical environment of the optic nerve head in glaucoma
JC Downs, MD Roberts, CF Burgoyne
Optometry and Vision Science 85 (6), E425-E435, 2008
2962008
3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: lamina cribrosa and peripapillary scleral position and thickness
H Yang, JC Downs, C Girkin, L Sakata, A Bellezza, H Thompson, ...
Investigative ophthalmology & visual science 48 (10), 4597-4607, 2007
2902007
Glaucomatous cupping of the lamina cribrosa: a review of the evidence for active progressive remodeling as a mechanism
JC Downs, MD Roberts, IA Sigal
Experimental eye research 93 (2), 133-140, 2011
2822011
Viscoelastic material properties of the peripapillary sclera in normal and early-glaucoma monkey eyes
JC Downs, JKF Suh, KA Thomas, AJ Bellezza, RT Hart, CF Burgoyne
Investigative ophthalmology & visual science 46 (2), 540-546, 2005
2722005
Biomechanical changes in the sclera of monkey eyes exposed to chronic IOP elevations
MJA Girard, JKF Suh, M Bottlang, CF Burgoyne, JC Downs
Investigative ophthalmology & visual science 52 (8), 5656-5669, 2011
2602011
Premise and prediction—how optic nerve head biomechanics underlies the susceptibility and clinical behavior of the aged optic nerve head
CF Burgoyne, JC Downs
Journal of glaucoma 17 (4), 318-328, 2008
2522008
Scleral biomechanics in the aging monkey eye
MJA Girard, JKF Suh, M Bottlang, CF Burgoyne, JC Downs
Investigative ophthalmology & visual science 50 (11), 5226-5237, 2009
2502009
Three-dimensional reconstruction of normal and early glaucoma monkey optic nerve head connective tissues
CF Burgoyne, JC Downs, AJ Bellezza, RT Hart
Investigative ophthalmology & visual science 45 (12), 4388-4399, 2004
2382004
Remodeling of the connective tissue microarchitecture of the lamina cribrosa in early experimental glaucoma
MD Roberts, V Grau, J Grimm, J Reynaud, AJ Bellezza, CF Burgoyne, ...
Investigative ophthalmology & visual science 50 (2), 681-690, 2009
2262009
Three-dimensional histomorphometry of the normal and early glaucomatous monkey optic nerve head: neural canal and subarachnoid space architecture
JC Downs, H Yang, C Girkin, L Sakata, A Bellezza, H Thompson, ...
Investigative ophthalmology & visual science 48 (7), 3195-3208, 2007
1872007
Posterior (outward) migration of the lamina cribrosa and early cupping in monkey experimental glaucoma
H Yang, G Williams, JC Downs, IA Sigal, MD Roberts, H Thompson, ...
Investigative ophthalmology & visual science 52 (10), 7109-7121, 2011
1852011
IOP-induced lamina cribrosa displacement and scleral canal expansion: an analysis of factor interactions using parameterized eye-specific models
IA Sigal, H Yang, MD Roberts, CF Burgoyne, JC Downs
Investigative ophthalmology & visual science 52 (3), 1896-1907, 2011
1772011
3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: prelaminar neural tissues and cupping
H Yang, JC Downs, A Bellezza, H Thompson, CF Burgoyne
Investigative ophthalmology & visual science 48 (11), 5068-5084, 2007
1762007
Peripapillary and posterior scleral mechanics—part II: experimental and inverse finite element characterization
MJA Girard, JC Downs, M Bottlang, CF Burgoyne, JKF Suh
1632009
24-hour IOP telemetry in the nonhuman primate: implant system performance and initial characterization of IOP at multiple timescales
JC Downs, CF Burgoyne, WP Seigfreid, JF Reynaud, NG Strouthidis, ...
Investigative ophthalmology & visual science 52 (10), 7365-7375, 2011
1582011
Optic nerve head biomechanics in aging and disease
JC Downs
Experimental eye research 133, 19-29, 2015
1542015
Correlation between local stress and strain and lamina cribrosa connective tissue volume fraction in normal monkey eyes
MD Roberts, Y Liang, IA Sigal, J Grimm, J Reynaud, A Bellezza, ...
Investigative ophthalmology & visual science 51 (1), 295-307, 2010
1472010
Age-and race-related differences in human scleral material properties
R Grytz, MA Fazio, V Libertiaux, L Bruno, S Gardiner, CA Girkin, ...
Investigative ophthalmology & visual science 55 (12), 8163-8172, 2014
1462014
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