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Michael B. Winter
Michael B. Winter
CytomX Therapeutics, UCSF, UC Berkeley
E-mail confirmado em ucsf.edu
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Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter
JM Kim, S Wu, TM Tomasiak, C Mergel, MB Winter, SB Stiller, ...
Nature 517 (7534), 396-400, 2015
1282015
Immunoproteasome functions explained by divergence in cleavage specificity and regulation
MB Winter, F La Greca, S Arastu-Kapur, F Caiazza, P Cimermancic, ...
Elife 6, e27364, 2017
842017
Global identification of biofilm-specific proteolysis in Candida albicans
MB Winter, EC Salcedo, MB Lohse, N Hartooni, M Gulati, H Sanchez, ...
MBio 7 (5), 10.1128/mbio. 01514-16, 2016
732016
Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain
MB Winter, MA Herzik Jr, J Kuriyan, MA Marletta
Proceedings of the National Academy of Sciences 108 (43), E881-E889, 2011
672011
Ru-Porphyrin Protein Scaffolds for Sensing O2
MB Winter, EJ McLaurin, SY Reece, C Olea Jr, DG Nocera, MA Marletta
Journal of the American Chemical Society 132 (16), 5582-5583, 2010
622010
Porphyrin-substituted H-NOX proteins as high-relaxivity MRI contrast agents
MB Winter, PJ Klemm, CM Phillips-Piro, KN Raymond, MA Marletta
Inorganic chemistry 52 (5), 2277-2279, 2013
542013
The rational design of therapeutic peptides for aminopeptidase N using a substrate-based approach
S Joshi, L Chen, MB Winter, YL Lin, Y Yang, M Shapovalova, PM Smith, ...
Scientific reports 7 (1), 1424, 2017
422017
Design and synthesis of C5 methylated L-arginine analogues as active site probes for nitric oxide synthase
NI Martin, JJ Woodward, MB Winter, WT Beeson, MA Marletta
Journal of the American Chemical Society 129 (41), 12563-12570, 2007
402007
Global substrate specificity profiling of post‐translational modifying enzymes
SL Ivry, NO Meyer, MB Winter, MF Bohn, GM Knudsen, AJ O'Donoghue, ...
Protein Science 27 (3), 584-594, 2018
382018
The multifaceted roles of tumor-associated proteases and harnessing their activity for prodrug activation
O Vasiljeva, DR Hostetter, SJ Moore, MB Winter
Biological Chemistry 400 (8), 965-977, 2019
362019
Structure and Properties of a Bis-Histidyl Ligated Globin from Caenorhabditis elegans,
J Yoon, MA Herzik Jr, MB Winter, R Tran, C Olea Jr, MA Marletta
Biochemistry 49 (27), 5662-5670, 2010
352010
Imaging active urokinase plasminogen activator in prostate cancer
AM LeBeau, N Sevillano, K Markham, MB Winter, ST Murphy, ...
Cancer research 75 (7), 1225-1235, 2015
292015
Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition
D Schneidman-Duhovny, N Khuri, GQ Dong, MB Winter, E Shifrut, ...
PloS one 13 (11), e0206654, 2018
262018
Multiplex substrate profiling by mass spectrometry for kinases as a method for revealing quantitative substrate motifs
NO Meyer, AJ O’Donoghue, U Schulze-Gahmen, M Ravalin, SM Moss, ...
Analytical chemistry 89 (8), 4550-4558, 2017
202017
Probing domain interactions in soluble guanylate cyclase
ER Derbyshire, MB Winter, M Ibrahim, S Deng, TG Spiro, MA Marletta
Biochemistry 50 (20), 4281-4290, 2011
202011
A probody T cell–engaging bispecific antibody targeting EGFR and CD3 inhibits colon cancer growth with limited toxicity
LM Boustany, SL LaPorte, L Wong, C White, V Vinod, J Shen, W Yu, ...
Cancer Research 82 (22), 4288-4298, 2022
172022
4, 4-Difluorinated analogues of l-arginine and NG-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase
NI Martin, JJ Woodward, MB Winter, MA Marletta
Bioorganic & medicinal chemistry letters 19 (6), 1758-1762, 2009
152009
Global identification of biofilm-specific proteolysis in Candida albicans. mBio 7: e01514-16
MB Winter, EC Salcedo, MB Lohse, N Hartooni, M Gulati, H Sanchez, ...
102016
Evidence of intratumoral localization, activation, and immunomodulatory effect of CX-072, a probody therapeutic targeting PD-L1, in a phase I/II trial
S Lyman, A Naing, IA Zein, Y Ru, B Howng, MB Winter, O Vasiljeva, ...
American Society of Clinical Oncology Virtual Meeting, 29-31, 2020
92020
An Escherichia coli Expression-Based Approach for Porphyrin Substitution in Heme Proteins
MB Winter, JJ Woodward, MA Marletta
Cytochrome P450 Protocols, 95-106, 2013
92013
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Artigos 1–20