A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses DC Jackson, YF Lau, T Le, A Suhrbier, G Deliyannis, C Cheers, C Smith, ... Proceedings of the National Academy of Sciences 101 (43), 15440-15445, 2004 | 305 | 2004 |
Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease JL McAuley, MD Tate, CJ MacKenzie-Kludas, A Pinar, W Zeng, A Stutz, ... PLoS pathogens 9 (5), e1003392, 2013 | 258 | 2013 |
Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines W Zeng, S Ghosh, YF Lau, LE Brown, DC Jackson The Journal of Immunology 169 (9), 4905-4912, 2002 | 235 | 2002 |
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses M Koutsakos, PT Illing, THO Nguyen, NA Mifsud, JC Crawford, S Rizzetto, ... Nature immunology 20 (5), 613-625, 2019 | 201 | 2019 |
New multi-determinant strategy for a group A streptococcal vaccine designed for the Australian Aboriginal population ER Brandt, KS Sriprakash, RI Hobb, WA Hayman, W Zeng, MR Batzloff, ... Nature medicine 6 (4), 455-459, 2000 | 189 | 2000 |
Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2 HH Alphs, R Gambhira, B Karanam, JN Roberts, S Jagu, JT Schiller, ... Proceedings of the National Academy of Sciences 105 (15), 5850-5855, 2008 | 188 | 2008 |
Intranasal administration of the TLR2 agonist Pam2Cys provides rapid protection against influenza in mice ACL Tan, EJ Mifsud, W Zeng, K Edenborough, J McVernon, LE Brown, ... Molecular pharmaceutics 9 (9), 2710-2718, 2012 | 119 | 2012 |
Chitosan microparticles and nanoparticles as biocompatible delivery vehicles for peptide and protein-based immunocontraceptive vaccines BY Chua, M Al Kobaisi, W Zeng, D Mainwaring, DC Jackson Molecular Pharmaceutics 9 (1), 81-90, 2012 | 117 | 2012 |
Induction of Long-Term Memory CD8+ T Cells for Recall of Viral Clearing Responses against Influenza Virus G Deliyannis, DC Jackson, NJ Ede, W Zeng, I Hourdakis, E Sakabetis, ... Journal of virology 76 (9), 4212-4221, 2002 | 102 | 2002 |
Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS … EH Nardin, JM Calvo-Calle, GA Oliveira, P Clavijo, R Nussenzweig, ... Vaccine 16 (6), 590-600, 1998 | 102 | 1998 |
Natural peptides as building blocks for the synthesis of large protein-like molecules with hydrazone and oxime linkages K Rose, W Zeng, PO Regamey, IV Chernushevich, KG Standing, ... Bioconjugate chemistry 7 (5), 552-556, 1996 | 102 | 1996 |
Bioactivity in an aggrecan 32‐mer fragment is mediated via Toll‐like receptor 2 S Lees, SB Golub, K Last, W Zeng, DC Jackson, P Sutton, AJ Fosang Arthritis & rheumatology 67 (5), 1240-1249, 2015 | 95 | 2015 |
Intranasal lipopeptide primes lung‐resident memory CD8+ T cells for long‐term pulmonary protection against influenza G Deliyannis, K Kedzierska, YF Lau, W Zeng, SJ Turner, DC Jackson, ... European journal of immunology 36 (3), 770-778, 2006 | 92 | 2006 |
Herpes simplex virus antigens directly activate NK cells via TLR2, thus facilitating their presentation to CD4 T lymphocytes M Kim, NR Osborne, W Zeng, H Donaghy, K McKinnon, DC Jackson, ... The Journal of Immunology 188 (9), 4158-4170, 2012 | 88 | 2012 |
Intranasal vaccination with a lipopeptide containing a conformationally constrained conserved minimal peptide, a universal T cell epitope, and a self-adjuvanting lipid protects … MR Batzloff, J Hartas, W Zeng, DC Jackson, MF Good The Journal of infectious diseases 194 (3), 325-330, 2006 | 87 | 2006 |
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model PC Proud, D Tsitoura, RJ Watson, BY Chua, MJ Aram, KR Bewley, ... EBioMedicine 63, 2021 | 86 | 2021 |
Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer JR Wallace, KM Mangas, JL Porter, R Marcsisin, SJ Pidot, B Howden, ... PLoS neglected tropical diseases 11 (4), e0005553, 2017 | 85 | 2017 |
Tear interferon-gamma as a biomarker for evaporative dry eye disease DC Jackson, W Zeng, CY Wong, EJ Mifsud, NA Williamson, CS Ang, ... Investigative ophthalmology & visual science 57 (11), 4824-4830, 2016 | 85 | 2016 |
Lipid-containing mimetics of natural triggers of innate immunity as CTL-inducing influenza vaccines YF Lau, G Deliyannis, W Zeng, A Mansell, DC Jackson, LE Brown International immunology 18 (12), 1801-1813, 2006 | 80 | 2006 |
Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens W Zeng, DC Jackson, J Murray, K Rose, LE Brown Vaccine 18 (11-12), 1031-1039, 2000 | 78 | 2000 |