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Adam Kimple, MD/PhD
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SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ...
Cell 182 (2), 429-446. e14, 2020
14332020
SARS-CoV-2 infection of the oral cavity and saliva
N Huang, P Pérez, T Kato, Y Mikami, K Okuda, RC Gilmore, CD Conde, ...
Nature medicine 27 (5), 892-903, 2021
6772021
Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review
AJ Shapiro, MA Zariwala, T Ferkol, SD Davis, SD Sagel, SD Dell, ...
Pediatric pulmonology 51 (2), 115-132, 2016
3762016
Structural and evolutionary division of phosphotyrosine binding (PTB) domains
MT Uhlik, B Temple, S Bencharit, AJ Kimple, DP Siderovski, GL Johnson
Journal of molecular biology 345 (1), 1-20, 2005
3122005
Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets
AJ Kimple, DE Bosch, PM Giguère, DP Siderovski
Pharmacological reviews 63 (3), 728-749, 2011
3102011
GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling
CA Johnston, JP Taylor, Y Gao, AJ Kimple, JC Grigston, JG Chen, ...
Proceedings of the National Academy of Sciences 104 (44), 17317-17322, 2007
2402007
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits
M Soundararajan, FS Willard, AJ Kimple, AP Turnbull, LJ Ball, GA Schoch, ...
Proceedings of the National Academy of Sciences 105 (17), 6457-6462, 2008
2152008
PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-κB activation
K Nakamura, AJ Kimple, DP Siderovski, GL Johnson
Journal of biological chemistry 285 (3), 2077-2089, 2010
1382010
Surgical treatments for otitis media with effusion: a systematic review
IF Wallace, ND Berkman, KN Lohr, MF Harrison, AJ Kimple, MJ Steiner
Pediatrics 133 (2), 296-311, 2014
1312014
Regulators of G-protein signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity
NA Lambert, CA Johnston, SD Cappell, S Kuravi, AJ Kimple, FS Willard, ...
Proceedings of the National Academy of Sciences 107 (15), 7066-7071, 2010
1012010
Reducing nasal morbidity after skull base reconstruction with the nasoseptal flap: free middle turbinate mucosal grafts
AJ Kimple, WD Leight, SA Wheless, AM Zanation
The Laryngoscope 122 (9), 1920-1924, 2012
842012
Structural determinants of G-protein α subunit selectivity by regulator of G-protein signaling 2 (RGS2)
AJ Kimple, M Soundararajan, SQ Hutsell, AK Roos, DJ Urban, V Setola, ...
Journal of Biological Chemistry 284 (29), 19402-19411, 2009
842009
Otitis media with effusion: comparative effectiveness of treatments
ND Berkman, IF Wallace, MJ Steiner, M Harrison, AM Greenblatt, KN Lohr, ...
832013
High-affinity immobilization of proteins using biotin-and GST-based coupling strategies
SQ Hutsell, RJ Kimple, DP Siderovski, FS Willard, AJ Kimple
Surface Plasmon Resonance: Methods and Protocols, 75-90, 2010
782010
Numerical evaluation of spray position for improved nasal drug delivery
S Basu, LT Holbrook, K Kudlaty, O Fasanmade, J Wu, A Burke, ...
Scientific reports 10 (1), 10568, 2020
692020
The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face
AJ Kimple, FS Willard, PM Giguère, CA Johnston, V Mocanu, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774 (9), 1213-1220, 2007
602007
A capture coupling method for the covalent immobilization of hexahistidine tagged proteins for surface plasmon resonance
AJ Kimple, RE Muller, DP Siderovski, FS Willard
Surface Plasmon Resonance: Methods and Protocols, 91-100, 2010
572010
A direct fluorescence-based assay for RGS domain GTPase accelerating activity
FS Willard, AJ Kimple, CA Johnston, DP Siderovski
Analytical biochemistry 340 (2), 341-351, 2005
572005
Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector
FS Willard, MD Willard, AJ Kimple, M Soundararajan, EA Oestreich, X Li, ...
PLoS One 4 (3), e4884, 2009
552009
Integrated single-cell atlases reveal an oral SARS-CoV-2 infection and transmission axis
N Huang, P Perez, T Kato, Y Mikami, K Okuda, RC Gilmore, ...
MedRxiv, 2020.10. 26.20219089, 2020
542020
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