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David Gavaghan
David Gavaghan
Professor of Computational Biology, University of Oxford
E-mail confirmado em cs.ox.ac.uk
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Assessing the quality of reports of randomized clinical trials: is blinding necessary?
AR Jadad, RA Moore, D Carroll, C Jenkinson, DJM Reynolds, ...
Controlled clinical trials 17 (1), 1-12, 1996
249521996
Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature
JAC Sterne, D Gavaghan, M Egger
Journal of clinical epidemiology 53 (11), 1119-1129, 2000
23532000
Size is everything–large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects
RA Moore, D Gavaghan, MR Tramer, SL Collins, HJ McQuay
Pain 78 (3), 209-216, 1998
5231998
Chaste: an open source C++ library for computational physiology and biology
GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ...
PLoS computational biology 9 (3), e1002970, 2013
5132013
Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk
GR Mirams, Y Cui, A Sher, M Fink, J Cooper, BM Heath, NC McMahon, ...
Cardiovascular research 91 (1), 53-61, 2011
3442011
An evaluation of homogeneity tests in meta-analyses in pain using simulations of individual patient data
DJ Gavaghan, RA Moore, HJ McQuay
Pain 85 (3), 415-424, 2000
3322000
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
3082009
Troubling trends in scientific software use
LN Joppa, G McInerny, R Harper, L Salido, K Takeda, K O'Hara, ...
Science 340 (6134), 814-815, 2013
2622013
Metabolic changes during carcinogenesis: potential impact on invasiveness
K Smallbone, RA Gatenby, RJ Gillies, PK Maini, DJ Gavaghan
Journal of theoretical biology 244 (4), 703-713, 2007
2492007
Multi-scale computational modelling in biology and physiology
J Southern, J Pitt-Francis, J Whiteley, D Stokeley, H Kobashi, R Nobes, ...
Progress in biophysics and molecular biology 96 (1-3), 60-89, 2008
2382008
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
JM Osborne, AG Fletcher, JM Pitt-Francis, PK Maini, DJ Gavaghan
PLoS computational biology 13 (2), e1005387, 2017
2312017
Oral morphine in cancer pain: influences on morphine and metabolite concentration
HJ McQuay, D Carroll, CC Faura, DJ Gavaghan, CW Hand, RA Moore
Clinical Pharmacology & Therapeutics 48 (3), 236-244, 1990
2161990
Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function
MJ Bishop, G Plank, RAB Burton, JE Schneider, DJ Gavaghan, V Grau, ...
American Journal of Physiology-Heart and Circulatory Physiology 298 (2 …, 2010
2132010
Generation of histo-anatomically representative models of the individual heart: tools and application
G Plank, RAB Burton, P Hales, M Bishop, T Mansoori, MO Bernabeu, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2009
2072009
The role of acidity in solid tumour growth and invasion
K Smallbone, DJ Gavaghan, RA Gatenby, PK Maini
Journal of theoretical biology 235 (4), 476-484, 2005
2022005
Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics
A Moore, H McQuay, D Gavaghan
PAIN® 66 (2-3), 229-237, 1996
1921996
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
1872009
Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: use of pain intensity and visual analogue scales
A Moore, O Moore, H McQuay, D Gavaghan
Pain 69 (3), 311-315, 1997
1841997
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework
AG Fletcher, JM Osborne, PK Maini, DJ Gavaghan
Progress in biophysics and molecular biology 113 (2), 299-326, 2013
1812013
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ...
Journal of molecular and cellular cardiology 96, 49-62, 2016
1652016
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