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Andrew L Lee
Andrew L Lee
Professor of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill
E-mail confirmado em unc.edu - Página inicial
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Redistribution and loss of side chain entropy upon formation of a calmodulin–peptide complex
AL Lee, SA Kinnear, AJ Wand
Nature structural biology 7 (1), 72-77, 2000
4132000
Hidden dynamic allostery in a PDZ domain
CM Petit, J Zhang, PJ Sapienza, EJ Fuentes, AL Lee
Proceedings of the National Academy of Sciences 106 (43), 18249-18254, 2009
3682009
Microscopic origins of entropy, heat capacity and the glass transition in proteins
AL Lee, AJ Wand
Nature 411 (6836), 501-504, 2001
3602001
Ligand-dependent dynamics and intramolecular signaling in a PDZ domain
EJ Fuentes, CJ Der, AL Lee
Journal of molecular biology 335 (4), 1105-1115, 2004
2672004
Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor
CL Partch, MW Clarkson, S Özgür, AL Lee, A Sancar
Biochemistry 44 (10), 3795-3805, 2005
2262005
Dynamic coupling and allosteric behavior in a nonallosteric protein
MW Clarkson, SA Gilmore, MH Edgell, AL Lee
Biochemistry 45 (25), 7693-7699, 2006
1562006
Evaluation of energetic and dynamic coupling networks in a PDZ domain protein
EJ Fuentes, SA Gilmore, RV Mauldin, AL Lee
Journal of molecular biology 364 (3), 337-351, 2006
1412006
Comparison of 2H and 13C NMR Relaxation Techniques for the Study of Protein Methyl Group Dynamics in Solution
AL Lee, PF Flynn, AJ Wand
Journal of the American Chemical Society 121 (12), 2891-2902, 1999
1361999
Assessing potential bias in the determination of rotational correlation times of proteins by NMR relaxation
AL Lee, AJ Wand
Journal of biomolecular NMR 13, 101-112, 1999
1251999
Temperature Dependence of the Internal Dynamics of a Calmodulin− Peptide Complex
AL Lee, KA Sharp, JK Kranz, XJ Song, AJ Wand
Biochemistry 41 (46), 13814-13825, 2002
1212002
Mapping allosteric communications within individual proteins
J Wang, A Jain, LR McDonald, C Gambogi, AL Lee, NV Dokholyan
Nature communications 11 (1), 3862, 2020
1152020
Using NMR to study fast dynamics in proteins: methods and applications
PJ Sapienza, AL Lee
Current opinion in pharmacology 10 (6), 723-730, 2010
1032010
Interaction of the sex‐lethal RNA binding domains with RNA.
R Kanaar, AL Lee, DZ Rudner, DE Wemmer, DC Rio
The EMBO Journal 14 (18), 4530-4539, 1995
1011995
Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c
MW Clarkson, AL Lee
Biochemistry 43 (39), 12448-12458, 2004
1002004
Direct demonstration of structural similarity between native and denatured eglin C
S Ohnishi, AL Lee, MH Edgell, D Shortle
Biochemistry 43 (14), 4064-4070, 2004
932004
Evidence for dynamics in proteins as a mechanism for ligand dissociation
MJ Carroll, RV Mauldin, AV Gromova, SF Singleton, EJ Collins, AL Lee
Nature chemical biology 8 (3), 246-252, 2012
892012
Dynamic dysfunction in dihydrofolate reductase results from antifolate drug binding: modulation of dynamics within a structural state
RV Mauldin, MJ Carroll, AL Lee
Structure 17 (3), 386-394, 2009
892009
Improved labeling strategy for 13C relaxation measurements of methyl groups in proteins
AL Lee, JL Urbauer, AJ Wand
Journal of biomolecular NMR 9, 437-440, 1997
851997
Phosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate …
J Zhang, CM Petit, DS King, AL Lee
Journal of Biological Chemistry 286 (48), 41776-41785, 2011
812011
Frameworks for understanding long-range intra-protein communication
AL Lee
Current Protein and Peptide Science 10 (2), 116-127, 2009
772009
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Artigos 1–20