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Martin Larhammar
Martin Larhammar
BioArctic AB
E-mail confirmado em bioarctic.se
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Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice
LS Andersson, M Larhammar, F Memic, H Wootz, D Schwochow, ...
Nature 488 (7413), 642-646, 2012
5002012
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth
E Markljung, L Jiang, JD Jaffe, TS Mikkelsen, O Wallerman, M Larhammar, ...
PLoS biology 7 (12), e1000256, 2009
2112009
Alterations in the motor neuron–renshaw cell circuit in the Sod1G93A mouse model
H Wootz, E FitzSimons‐Kantamneni, M Larhammar, TM Rotterman, ...
Journal of Comparative Neurology 521 (7), 1449-1469, 2013
842013
The Ste20 family kinases MAP4K4, MINK1, and TNIK converge to regulate stress-induced JNK signaling in neurons
M Larhammar, S Huntwork-Rodriguez, Y Rudhard, A Sengupta-Ghosh, ...
Journal of Neuroscience 37 (46), 11074-11084, 2017
812017
Cell death and neurodegeneration
BJ Andreone, M Larhammar, JW Lewcock
Cold Spring Harbor perspectives in biology 12 (2), a036434, 2020
702020
Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult
M Larhammar, S Huntwork-Rodriguez, Z Jiang, H Solanoy, ...
Elife 6, e20725, 2017
682017
Characterization of Dmrt3-derived neurons suggest a role within locomotor circuits
S Perry, M Larhammar, J Vieillard, C Nagaraja, MM Hilscher, A Tafreshiha, ...
Journal of Neuroscience 39 (10), 1771-1782, 2019
452019
SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis
M Larhammar, K Patra, M Blunder, L Emilsson, C Peuckert, E Arvidsson, ...
Biological psychiatry 77 (6), 526-536, 2015
452015
Firing properties of Renshaw cells defined by Chrna2 are modulated by hyperpolarizing and small conductance ion currents Ih and ISK
S Perry, H Gezelius, M Larhammar, MM Hilscher, B Lamotte d'Incamps, ...
European Journal of Neuroscience 41 (7), 889-900, 2015
322015
The synaptic protein encoded by the gene Slc10A4 suppresses epileptiform activity and regulates sensitivity to cholinergic chemoconvulsants
J Zelano, S Mikulovic, K Patra, M Kühnemund, M Larhammar, L Emilsson, ...
Experimental neurology 239, 73-81, 2013
292013
Developmental disruption of recurrent inhibitory feedback results in compensatory adaptation in the Renshaw cell–motor neuron circuit
A Enjin, S Perry, MM Hilscher, C Nagaraja, M Larhammar, H Gezelius, ...
Journal of Neuroscience 37 (23), 5634-5647, 2017
252017
Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice
A Hånell, F Clausen, A Djupsjö, A Vallstedt, K Patra, C Israelsson, ...
Journal of neurotrauma 29 (17), 2660-2671, 2012
202012
Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of …
RA Craig, BM Fox, C Hu, KW Lexa, M Osipov, AP Thottumkara, ...
Journal of Medicinal Chemistry 65 (24), 16290-16312, 2022
62022
DNL343 is an investigational CNS penetrant eIF2B activator that prevents and reverses the effects of neurodegeneration caused by the Integrated Stress Response
E Yulyaningsih, JH Suh, MH Fanok, R Chau, H Solanoy, R Takahashi, ...
bioRxiv, 2023.08. 21.554203, 2023
12023
SARM1 activation and its downstream pathways are distinct in neuronal compartments
T Miyamoto, C Kim, J Chow, JC Dugas, J DeGroot, AL Bagdasarian, ...
bioRxiv, 2022.04. 27.489702, 2022
12022
Neuronal Networks of Movement: Slc10a4 as a Modulator & Dmrt3 as a Gait-keeper
M Larhammar
Acta Universitatis Upsaliensis, 2014
12014
Development of spinal motor circuits in the absence of VIAAT-mediated Renshaw cell signaling
A Enjin, KE Leão, A Eriksson, M Larhammar, H Gezelius, ...
12011
SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons
T Miyamoto, C Kim, J Chow, JC Dugas, J DeGroot, AL Bagdasarian, ...
Journal of Biological Chemistry 300 (2), 2024
2024
Dmrt3 derived spinal cord neurons regulate locomotor coordination across different speeds
S Perry, M Larhammar, C Nagaraja, MM Hilscher, A Tafreshiha, E Potter, ...
2016
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Artigos 1–19