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Lucas TREPS
Lucas TREPS
CRCI2NA, UMR 1307 Inserm / UMR 6075 CNRS, Nantes, France
E-mail confirmado em univ-nantes.fr
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Single-cell transcriptome atlas of murine endothelial cells
J Kalucka, LPMH de Rooij, J Goveia, K Rohlenova, SJ Dumas, E Meta, ...
Cell 180 (4), 764-779. e20, 2020
8372020
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy
AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ...
Cancer cell 30 (6), 968-985, 2016
5522016
Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders
S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ...
The EMBO journal 33 (18), 2020-2039, 2014
5292014
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes, BW Wong, P Carmeliet
Physiological reviews 98 (1), 3-58, 2018
4682018
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates
J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ...
Cancer cell 37 (1), 21-36. e13, 2020
3332020
Basic and therapeutic aspects of angiogenesis updated
G Eelen, L Treps, X Li, P Carmeliet
Circulation research 127 (2), 310-329, 2020
3102020
Glioblastoma stem-like cells secrete the pro-angiogenic VEGF-A factor in extracellular vesicles
L Treps, R Perret, S Edmond, D Ricard, J Gavard
Journal of extracellular vesicles 6 (1), 1359479, 2017
2462017
Endothelial cell metabolism in health and disease: impact of hypoxia
BW Wong, E Marsch, L Treps, M Baes, P Carmeliet
The EMBO journal 36 (15), 2187-2203, 2017
2382017
Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis
J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ...
Cell metabolism 28 (6), 881-894. e13, 2018
2092018
Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis
K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ...
Cell metabolism 31 (4), 862-877. e14, 2020
1922020
Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation
U Bruning, F Morales-Rodriguez, J Kalucka, J Goveia, F Taverna, ...
Cell metabolism 28 (6), 866-880. e15, 2018
1802018
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ...
Nature 561 (7721), 63-69, 2018
1562018
Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma
L Treps, S Edmond, E Harford-Wright, EM Galan-Moya, A Schmitt, S Azzi, ...
Oncogene 35 (20), 2615-2623, 2016
1202016
Central role of metabolism in endothelial cell function and vascular disease
L Bierhansl, LC Conradi, L Treps, M Dewerchin, P Carmeliet
Physiology 32 (2), 126-140, 2017
1032017
Pharmacological targeting of apelin impairs glioblastoma growth
E Harford-Wright, G Andre-Gregoire, KA Jacobs, L Treps, S Le Gonidec, ...
Brain 140 (11), 2939-2954, 2017
932017
Endothelial cell metabolism: a novel player in atherosclerosis? Basic principles and therapeutic opportunities
A Pircher, L Treps, N Bodrug, P Carmeliet
Atherosclerosis 253, 247-257, 2016
862016
Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation
A Le Guelte, EM Galan-Moya, J Dwyer, L Treps, G Kettler, JK Hebda, ...
Journal of cell Science 125 (17), 4137-4146, 2012
822012
EndoDB: a database of endothelial cell transcriptomics data
S Khan, F Taverna, K Rohlenova, L Treps, V Geldhof, L de Rooij, L Sokol, ...
Nucleic acids research 47 (D1), D736-D744, 2019
792019
Manipulating angiogenesis by targeting endothelial metabolism: hitting the engine rather than the drivers—a new perspective?
L Treps, LC Conradi, U Harjes, P Carmeliet
Pharmacological Reviews 68 (3), 872-887, 2016
572016
Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target
L Treps, S Faure, N Clere
Pharmacology & therapeutics 223, 107805, 2021
512021
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Artigos 1–20