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Bradley R. Kossmann
Bradley R. Kossmann
E-mail confirmado em student.gsu.edu
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Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space
WH Hudson, BR Kossmann, IMS de Vera, SW Chuo, ER Weikum, ...
Proceedings of the National Academy of Sciences 113 (2), 326-331, 2016
362016
Unexpected allosteric network contributes to LRH-1 co-regulator selectivity
PM Musille, BR Kossmann, JA Kohn, I Ivanov, EA Ortlund
Journal of Biological Chemistry 291 (3), 1411-1426, 2016
282016
Uncovering universal rules governing the selectivity of the archetypal DNA glycosylase TDG
T Dodd, C Yan, BR Kossmann, K Martin, I Ivanov
Proceedings of the National Academy of Sciences 115 (23), 5974-5979, 2018
232018
Secondary interaction interfaces with PCNA control conformational switching of DNA polymerase PolB from polymerization to editing
X Xu, C Yan, BR Kossmann, I Ivanov
The Journal of Physical Chemistry B 120 (33), 8379-8388, 2016
212016
Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft
BR Kossmann, M Abdelmalak, S Lopez, G Tender, C Yan, Y Pommier, ...
Bioorganic & medicinal chemistry letters 26 (14), 3232-3236, 2016
182016
Alkylpurine glycosylase D employs DNA sculpting as a strategy to extrude and excise damaged bases
B Kossmann, I Ivanov
PLoS Computational Biology 10 (7), e1003704, 2014
42014
Computational Investigations of Biomolecular Motions and Interactions in Genomic Maintenance and Regulation
BR Kossmann
2017
Evolving allostery of the 3-ketosteroid family of nuclear receptors
B Kossmann, W Hudson, I Ivanov, E Ortlund
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
2016
Damage recognition and base extrusion strategies of DNA repair glycosylase enzyme
B Kossmann, I Ivanov
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
2016
Computational discovery of activating and repressing states for the liver receptor homologue 1 ligand binding domain
B Kossmann, P Musille, I Ivanov, E Ortlund
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
2016
An Allosteric Network in LRH‐1 Mediates Phospholipid‐Driven Gene Regulation
J Kohn, P Musille, B Kossmann, I Ivanov, E Ortlund
The FASEB Journal 29, 715.28, 2015
2015
Computational insights for the AlkD base extrusion strategy
BR Kossmann, I Ivanov
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
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Artigos 1–12