Victor Nizet
Victor Nizet
Distinguished Professor of Pediatrics and Pharmacy
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
HIF-1α is essential for myeloid cell-mediated inflammation
T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ...
Cell 112 (5), 645-657, 2003
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
J Rius, M Guma, C Schachtrup, K Akassoglou, AS Zinkernagel, V Nizet, ...
Nature 453 (7196), 807-811, 2008
Innate antimicrobial peptide protects the skin from invasive bacterial infection
V Nizet, T Ohtake, X Lauth, J Trowbridge, J Rudisill, RA Dorschner, ...
Nature 414 (6862), 454-457, 2001
Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis
AL Bisno, MA Gerber, JM Gwaltney Jr, EL Kaplan, RH Schwartz
Clinical infectious diseases 35 (2), 113-125, 2002
Skin microbiota: a source of disease or defence?
AL Cogen, V Nizet, RL Gallo
British journal of dermatology 158 (3), 442-455, 2008
Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
M Karin, T Lawrence, V Nizet
Cell 124 (4), 823-835, 2006
Infectious diseases of the fetus and newborn E-book
JS Remington, CB Wilson, V Nizet, JO Klein, Y Maldonado
Elsevier Health Sciences, 2010
HIF transcription factors, inflammation, and immunity
A Palazon, AW Goldrath, V Nizet, RS Johnson
Immunity 41 (4), 518-528, 2014
Development and use of personalized bacteriophage-based therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii infection
RT Schooley, B Biswas, JJ Gill, A Hernandez-Morales, J Lancaster, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 00954-17, 2017
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
Y Chen, R Corriden, Y Inoue, L Yip, N Hashiguchi, A Zinkernagel, V Nizet, ...
Science 314 (5806), 1792-1795, 2006
Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity
GY Liu, A Essex, JT Buchanan, V Datta, HM Hoffman, JF Bastian, J Fierer, ...
The Journal of experimental medicine 202 (2), 209-215, 2005
Disease manifestations and pathogenic mechanisms of group A Streptococcus
MJ Walker, TC Barnett, JD McArthur, JN Cole, CM Gillen, A Henningham, ...
Clinical microbiology reviews 27 (2), 264-301, 2014
DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps
JT Buchanan, AJ Simpson, RK Aziz, GY Liu, SA Kristian, M Kotb, ...
Current Biology 16 (4), 396-400, 2006
HIF-1α expression regulates the bactericidal capacity of phagocytes
C Peyssonnaux, V Datta, T Cramer, A Doedens, EA Theodorakis, ...
The Journal of clinical investigation 115 (7), 1806-1815, 2005
Interdependence of hypoxic and innate immune responses
V Nizet, RS Johnson
Nature Reviews Immunology 9 (9), 609-617, 2009
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
T Lawrence, M Bebien, GY Liu, V Nizet, M Karin
Nature 434 (7037), 1138-1143, 2005
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
C Peyssonnaux, AS Zinkernagel, RA Schuepbach, E Rankin, S Vaulont, ...
The Journal of clinical investigation 117 (7), 1926-1932, 2007
Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus
RA Dorschner, VK Pestonjamasp, S Tamakuwala, T Ohtake, J Rudisill, ...
Journal of Investigative Dermatology 117 (1), 91-97, 2001
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence
CI Liu, GY Liu, Y Song, F Yin, ME Hensler, WY Jeng, V Nizet, AHJ Wang, ...
Science 319 (5868), 1391-1394, 2008
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