| Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode Nɛ-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ... Chemistry & biology 15 (11), 1187-1197, 2008 | 401 | 2008 |
| Dicer partner proteins tune the length of mature miRNAs in flies and mammals R Fukunaga, BW Han, JH Hung, J Xu, Z Weng, PD Zamore Cell 151 (3), 533-546, 2012 | 262 | 2012 |
| The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer–editing conformation M Tukalo, A Yaremchuk, R Fukunaga, S Yokoyama, S Cusack Nature structural & molecular biology 12 (10), 923-930, 2005 | 198 | 2005 |
| Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease ES Cenik, R Fukunaga, G Lu, R Dutcher, Y Wang, TMT Hall, PD Zamore Molecular cell 42 (2), 172-184, 2011 | 172 | 2011 |
| dsRNA with 5′ overhangs contributes to endogenous and antiviral RNA silencing pathways in plants R Fukunaga, JA Doudna The EMBO journal 28 (5), 545-555, 2009 | 160 | 2009 |
| Crystallographic studies on multiple conformational states of active-site loops in pyrrolysyl-tRNA synthetase T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ... Journal of molecular biology 378 (3), 634-652, 2008 | 121 | 2008 |
| Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition R Fukunaga, S Yokoyama Nature structural & molecular biology 12 (10), 915-922, 2005 | 121 | 2005 |
| Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation R Fukunaga, S Yokoyama Journal of molecular biology 346 (1), 57-71, 2005 | 106 | 2005 |
| Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase R Fukunaga, S Yokoyama Journal of molecular biology 359 (4), 901-912, 2006 | 81 | 2006 |
| Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus M Kuratani, R Ishii, Y Bessho, R Fukunaga, T Sengoku, M Shirouzu, ... Journal of Biological Chemistry 280 (16), 16002-16008, 2005 | 73 | 2005 |
| Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea R Fukunaga, S Yokoyama Nature structural & molecular biology 14 (4), 272-279, 2007 | 63 | 2007 |
| Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei T Yanagisawa, R Ishii, R Fukunaga, O Nureki, S Yokoyama Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 62 | 2006 |
| Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine R Fukunaga, S Fukai, R Ishitani, O Nureki, S Yokoyama Journal of Biological Chemistry 279 (9), 8396-8402, 2004 | 61 | 2004 |
| Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization M Naganuma, S Sekine, R Fukunaga, S Yokoyama Proceedings of the National Academy of Sciences 106 (21), 8489-8494, 2009 | 59 | 2009 |
| Structural basis for non-cognate amino acid discrimination by the valyl-tRNA synthetase editing domain R Fukunaga, S Yokoyama Journal of Biological Chemistry 280 (33), 29937-29945, 2005 | 55 | 2005 |
| Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production SK Kandasamy, R Fukunaga Proceedings of the National Academy of Sciences 113 (49), 14031-14036, 2016 | 54 | 2016 |
| Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA: Cys-tRNA synthase from Archaeoglobus fulgidus R Fukunaga, S Yokoyama Journal of molecular biology 370 (1), 128-141, 2007 | 49 | 2007 |
| Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase HM Sasaki, S Sekine, T Sengoku, R Fukunaga, M Hattori, Y Utsunomiya, ... Proceedings of the National Academy of Sciences 103 (40), 14744-14749, 2006 | 49 | 2006 |
| Inorganic phosphate blocks binding of pre‐mi RNA to Dicer‐2 via its PAZ domain R Fukunaga, C Colpan, BW Han, PD Zamore The EMBO journal 33 (4), 371-384, 2014 | 43 | 2014 |
| Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models S Vakrou, R Fukunaga, DB Foster, L Sorensen, Y Liu, Y Guan, ... JCI insight 3 (6), 2018 | 37 | 2018 |
