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Seth Lucian Masters
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
33502013
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
RC Coll, AAB Robertson, JJ Chae, SC Higgins, R Muñoz-Planillo, ...
Nature medicine 21 (3), 248-255, 2015
22552015
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ...
Nature immunology 11 (10), 897-904, 2010
14112010
STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus
EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ...
New England Journal of Medicine 357 (10), 977-986, 2007
13082007
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
SL Masters, A Simon, I Aksentijevich, DL Kastner
Annual review of immunology 27, 621-668, 2009
13062009
An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist
I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ...
New England Journal of Medicine 360 (23), 2426-2437, 2009
10352009
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
AR Mridha, A Wree, AAB Robertson, MM Yeh, CD Johnson, ...
Journal of hepatology 66 (5), 1037-1046, 2017
8432017
The B30. 2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production
JJ Chae, G Wood, SL Masters, K Richard, G Park, BJ Smith, DL Kastner
Proceedings of the National Academy of Sciences 103 (26), 9982-9987, 2006
7252006
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ...
Nature communications 6 (1), 6282, 2015
5912015
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ...
Cell 157 (5), 1175-1188, 2014
5832014
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells
A Vasanthakumar, K Moro, A Xin, Y Liao, R Gloury, S Kawamoto, ...
Nature immunology 16 (3), 276-285, 2015
5372015
TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS
CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ...
Cell 183 (3), 636-649. e18, 2020
4952020
Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity
PR Nagareddy, M Kraakman, SL Masters, RA Stirzaker, DJ Gorman, ...
Cell metabolism 19 (5), 821-835, 2014
4762014
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production
M Haneklaus, M Gerlic, M Kurowska-Stolarska, AA Rainey, D Pich, ...
The Journal of Immunology 189 (8), 3795-3799, 2012
4722012
miR‐223: infection, inflammation and cancer
M Haneklaus, M Gerlic, LAJ O'Neill, SL Masters
Journal of internal medicine 274 (3), 215-226, 2013
4452013
Evidence that TLR4 is not a receptor for saturated fatty acids but mediates lipid-induced inflammation by reprogramming macrophage metabolism
GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, ...
Cell metabolism 27 (5), 1096-1110. e5, 2018
3842018
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation
FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ...
Cell 167 (1), 187-202. e17, 2016
3842016
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ...
Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017
3812017
Homeostasis-altering molecular processes as mechanisms of inflammasome activation
A Liston, SL Masters
Nature Reviews Immunology 17 (3), 208-214, 2017
3762017
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5
PJ Baker, D Boucher, D Bierschenk, C Tebartz, PG Whitney, DB D'Silva, ...
European journal of immunology 45 (10), 2918-2926, 2015
3482015
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