A toolkit for rapid modular construction of biological circuits in mammalian cells JP Fonseca, AR Bonny, GR Kumar, AH Ng, J Town, QC Wu, E Aslankoohi, ... ACS synthetic biology 8 (11), 2593-2606, 2019 | 54 | 2019 |
Cell confinement reveals a branched-actin independent circuit for neutrophil polarity BR Graziano, JP Town, E Sitarska, TL Nagy, M Fošnarič, S Penič, A Iglič, ... PLoS biology 17 (10), e3000457, 2019 | 53 | 2019 |
The WAVE complex associates with sites of saddle membrane curvature A Pipathsouk, RM Brunetti, JP Town, BR Graziano, A Breuer, PA Pellett, ... Journal of Cell Biology 220 (8), e202003086, 2021 | 37 | 2021 |
Cell protrusions and contractions generate long-range membrane tension propagation H De Belly, S Yan, HB da Rocha, S Ichbiah, JP Town, PJ Zager, ... Cell 186 (14), 3049-3061. e15, 2023 | 26 | 2023 |
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance D Mavor, KA Barlow, D Asarnow, Y Birman, D Britain, W Chen, EM Green, ... Biology Open 7 (7), bio036103, 2018 | 21 | 2018 |
Progressive enhancement of kinetic proofreading in T cell antigen discrimination from receptor activation to DAG generation DM Britain, JP Town, OD Weiner Elife 11, e75263, 2022 | 15 | 2022 |
Mechanosensitive mTORC2 independently coordinates leading and trailing edge polarity programs during neutrophil migration S Saha, JP Town, OD Weiner Molecular biology of the cell 34 (5), ar35, 2023 | 10 | 2023 |
WAVE complex self-organization templates lamellipodial formation A Pipathsouk, RM Brunetti, JP Town, A Breuer, PA Pellett, K Marchuk, ... bioRxiv, 836585, 2019 | 10 | 2019 |
Actin-driven protrusions generate rapid long-range membrane tension propagation in cells H De Belly, S Yan, HB da Rocha, S Ichbiah, JP Town, H Turlier, ... bioRxiv, 2022.09. 07.507005, 2022 | 8 | 2022 |
Assembly of genetic circuits with the mammalian toolKit JP Fonseca, AR Bonny, J Town, H El-Samad Bio-protocol 10 (5), e3547-e3547, 2020 | 4 | 2020 |
mTORC2 coordinates the leading and trailing edge cytoskeletal programs during neutrophil migration S Saha, JP Town, OD Weiner bioRxiv, 2022.03. 25.484773, 2022 | 2 | 2022 |
Local negative feedback of Rac activity at the leading edge underlies a pilot pseudopod-like program for amoeboid cell guidance JP Town, OD Weiner PLoS Biology 21 (9), e3002307, 2023 | 1 | 2023 |
Rac negative feedback links local PIP3 rate-of-change to dynamic control of neutrophil guidance J Town, O Weiner bioRxiv, 2022.12. 30.521706, 2022 | 1 | 2022 |
Cell-extrinsic mechanical forces restore neutrophil polarization in the absence of branched actin assembly B Graziano, J Town, T Nagy, M Fonari, S Peni, A Igli, V Kralj-Igli, N Gov, ... bioRxiv, 457119, 2018 | 1 | 2018 |
Do cell membranes support or resist tension propagation? H De Belly, S Yan, HB da Rocha, S Ichbiah, JP Town, H Turlier, ... Biophysical journal 122 (3), 269a, 2023 | | 2023 |
Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView T Kudo, AM Meireles, R Moncada, Y Chen, P Wu, J Gould, X Hu, ... bioRxiv, 2023.12. 26.573143, 2023 | | 2023 |
Decisive but not stubborn: How local inhibition tunes polarity in migrating neutrophils JP Town University of California, San Francisco, 2023 | | 2023 |
Research Advance: Extending chemical perturbations of the Ubiquitin fitness landscape in a classroom setting D Mavor, KA Barlow, D Asarnow, Y Birman, D Britain, W Chen, EM Green, ... bioRxiv, 139352, 2017 | | 2017 |