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Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome
S Ussar, NW Griffin, O Bezy, S Fujisaka, S Vienberg, S Softic, L Deng, ...
Cell metabolism 22 (3), 516-530, 2015
5692015
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
SB Biddinger, JT Haas, BB Yu, O Bezy, E Jing, W Zhang, TG Unterman, ...
Nature medicine 14 (7), 778-782, 2008
3872008
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
C Vernochet, A Mourier, O Bezy, Y Macotela, J Boucher, MJ Rardin, D An, ...
Cell metabolism 16 (6), 765-776, 2012
2552012
Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells
A Abderrahim-Ferkoune, O Bezy, C Chiellini, M Maffei, P Grimaldi, ...
Journal of lipid research 44 (5), 994-1000, 2003
1762003
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans
O Bezy, TT Tran, J Pihlajamäki, R Suzuki, B Emanuelli, J Winnay, MA Mori, ...
The Journal of clinical investigation 121 (6), 2504-2517, 2011
1682011
Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications
C Vernochet, F Damilano, A Mourier, O Bezy, MA Mori, G Smyth, ...
The FASEB Journal 28 (10), 4408, 2014
1622014
TRB3 blocks adipocyte differentiation through the inhibition of C/EBPβ transcriptional activity
O Bezy, C Vernochet, S Gesta, SR Farmer, CR Kahn
Molecular and cellular biology 27 (19), 6818-6831, 2007
1152007
Glypican-4 enhances insulin signaling via interaction with the insulin receptor and serves as a novel adipokine
S Ussar, O Bezy, M Blüher, CR Kahn
Diabetes 61 (9), 2289-2298, 2012
1082012
A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis
J Boucher, Y Macotela, O Bezy, MA Mori, K Kriauciunas, CR Kahn
Science signaling 3 (151), ra87-ra87, 2010
932010
Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration
S Gesta, O Bezy, MA Mori, Y Macotela, KY Lee, CR Kahn
Proceedings of the National Academy of Sciences 108 (7), 2771-2776, 2011
902011
Transdifferentiation of preadipose cells into smooth muscle-like cells: role of aortic carboxypeptidase-like protein
A Abderrahim-Ferkoune, O Bezy, S Astri-Roques, C Elabd, G Ailhaud, ...
Experimental cell research 293 (2), 219-228, 2004
872004
A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
MA Mori, M Liu, O Bezy, K Almind, H Shapiro, S Kasif, CR Kahn
Diabetes 59 (11), 2960-2971, 2010
762010
Metabolic syndrome: is Nlrp3 inflammasome a trigger or a target of insulin resistance?
MA Mori, O Bezy, CR Kahn
Circulation research 108 (10), 1160-1162, 2011
512011
Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein β, implicated in adipocyte differentiation
O Bezy, C Elabd, O Cochet, RK Petersen, K Kristiansen, C Dani, ...
Journal of Biological Chemistry 280 (12), 11432-11438, 2005
432005
Role of PKCδ in insulin sensitivity and skeletal muscle metabolism
M Li, SG Vienberg, O Bezy, BT O’Neill, CR Kahn
Diabetes 64 (12), 4023-4032, 2015
422015
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation
E Fung, L Kang, D Sapashnik, S Benard, A Sievers, Y Liu, G Yan, J Zhou, ...
Scientific reports 11 (1), 8921, 2021
142021
Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation
DM Breen, S Jagarlapudi, A Patel, C Zou, S Joaquim, X Li, L Kang, ...
Iscience 24 (6), 2021
102021
LPS induces rapid increase in GDF15 levels in mice, rats, and humans but is not required for anorexia in mice
AR Patel, H Frikke-Schmidt, O Bezy, PV Sabatini, N Rittig, N Jessen, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 322 (2 …, 2022
82022
Use of protein kinase c delta (pkcd) inhibitors to treat diabetes, obesity, and hepatic steatosis
CR Kahn, O Bezy
US Patent App. 13/497,172, 2012
72012
Attenuation of PKC δ enhances metabolic activity and promotes expansion of blood progenitors
TN Rao, MK Gupta, S Softic, LD Wang, YC Jang, T Thomou, O Bezy, ...
The EMBO Journal 37 (24), e100409, 2018
42018
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