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FRANCIS LEONARDO PAZINI
FRANCIS LEONARDO PAZINI
Laboratório de Neurobiologia da Depressão- UFSC
E-mail confirmado em posgrad.ufsc.br
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Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L.
DG Machado, MP Cunha, VB Neis, GO Balen, A Colla, LEB Bettio, ...
Food Chemistry 136 (2), 999-1005, 2013
1632013
Creatine, similar to ketamine, counteracts depressive-like behavior induced by corticosterone via PI3K/Akt/mTOR pathway
FL Pazini, MP Cunha, JM Rosa, ARS Colla, V Lieberknecht, Á Oliveira, ...
Molecular neurobiology 53, 6818-6834, 2016
1342016
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide–cGMP and PI3K/mTOR pathways
LEB Bettio, MP Cunha, J Budni, FL Pazini, Á Oliveira, AR Colla, ...
Behavioural brain research 234 (2), 137-148, 2012
1002012
Central irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice
A Siteneski, MP Cunha, V Lieberknecht, FL Pazini, K Gruhn, PS Brocardo, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 84, 294-303, 2018
742018
Involvement of PI3K/Akt signaling pathway and its downstream intracellular targets in the antidepressant-like effect of creatine
MP Cunha, J Budni, FK Ludka, FL Pazini, JM Rosa, Á Oliveira, MW Lopes, ...
Molecular neurobiology 53, 2954-2968, 2016
652016
Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice
ARS Colla, A Oliveira, FL Pazini, JM Rosa, LM Manosso, MP Cunha, ...
Pharmacology Biochemistry and Behavior 124, 108-116, 2014
582014
The antidepressant-like effect of physical activity on a voluntary running wheel
MP Cunha, A Oliveira, FL Pazini, DG Machado, LE Bettio, J Budni, ...
Med Sci Sports Exerc 45 (5), 851-859, 2013
572013
Therapeutic potential of ursolic acid to manage neurodegenerative and psychiatric diseases
AB Ramos-Hryb, FL Pazini, MP Kaster, ALS Rodrigues
Cns Drugs 31 (12), 1029-1041, 2017
512017
The antidepressant‐like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation
LEB Bettio, VB Neis, FL Pazini, PS Brocardo, AR Patten, J Gil‐Mohapel, ...
European Journal of Neuroscience 43 (8), 1006-1015, 2016
472016
The modulation of NMDA receptors and l-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test
MP Cunha, FL Pazini, FK Ludka, JM Rosa, Á Oliveira, J Budni, ...
Amino acids 47, 795-811, 2015
462015
Creatine prevents corticosterone-induced reduction in hippocampal proliferation and differentiation: possible implication for its antidepressant effect
FL Pazini, MP Cunha, D Azevedo, JM Rosa, A Colla, J de Oliveira, ...
Molecular neurobiology 54, 6245-6260, 2017
442017
Evidence for the involvement of 5-HT1A receptor in the acute antidepressant-like effect of creatine in mice
MP Cunha, FL Pazini, Á Oliveira, DG Machado, ALS Rodrigues
Brain Research Bulletin 95, 61-69, 2013
402013
Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A1 and A2A receptor activation
MP Cunha, FL Pazini, JM Rosa, AB Ramos-Hryb, Á Oliveira, MP Kaster, ...
Purinergic Signalling 11, 215-227, 2015
392015
Augmentation effect of ketamine by guanosine in the novelty-suppressed feeding test is dependent on mTOR signaling pathway
A Camargo, FL Pazini, JM Rosa, IAV Wolin, M Moretti, PB Rosa, VB Neis, ...
Journal of psychiatric research 115, 103-112, 2019
382019
The possible beneficial effects of creatine for the management of depression
FL Pazini, MP Cunha, ALS Rodrigues
Progress in Neuro-Psychopharmacology and Biological Psychiatry 89, 193-206, 2019
382019
The activation of α1-adrenoceptors is implicated in the antidepressant-like effect of creatine in the tail suspension test
MP Cunha, FL Pazini, Á Oliveira, LEB Bettio, JM Rosa, DG Machado, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 44, 39-50, 2013
382013
MPP+-Lesioned Mice: an Experimental Model of Motor, Emotional, Memory/Learning, and Striatal Neurochemical Dysfunctions
MP Cunha, FL Pazini, V Lieberknecht, J Budni, Á Oliveira, JM Rosa, ...
Molecular neurobiology 54, 6356-6377, 2017
372017
Antidepressant-like and pro-neurogenic effects of physical exercise: The putative role of FNDC5/irisin pathway
A Siteneski, G Olescowicz, FL Pazini, A Camargo, DB Fraga, PS Brocardo, ...
Journal of neural transmission 127, 355-370, 2020
342020
Ascorbic acid presents rapid behavioral and hippocampal synaptic plasticity effects
DB Fraga, AP Costa, G Olescowicz, A Camargo, FL Pazini, AE Freitas, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 96, 109757, 2020
302020
mTORC1-dependent signaling pathway underlies the rapid effect of creatine and ketamine in the novelty-suppressed feeding test
FL Pazini, JM Rosa, A Camargo, DB Fraga, M Moretti, A Siteneski, ...
Chemico-Biological Interactions 332, 109281, 2020
242020
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