Three-dimensional folding and functional organization principles of the Drosophila genome T Sexton, E Yaffe, E Kenigsberg, F Bantignies, B Leblanc, M Hoichman, ... Cell 148 (3), 458-472, 2012 | 2042 | 2012 |
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells S Schoenfelder, T Sexton, L Chakalova, NF Cope, A Horton, S Andrews, ... Nature genetics 42 (1), 53-61, 2010 | 814 | 2010 |
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus S Hadjur, LM Williams, NK Ryan, BS Cobb, T Sexton, P Fraser, AG Fisher, ... Nature 460 (7253), 410-413, 2009 | 630 | 2009 |
The role of chromosome domains in shaping the functional genome T Sexton, G Cavalli Cell 160 (6), 1049-1059, 2015 | 442 | 2015 |
Gene regulation through nuclear organization T Sexton, H Schober, P Fraser, SM Gasser Nature structural & molecular biology 14 (11), 1049-1055, 2007 | 305 | 2007 |
TADs are 3D structural units of higher-order chromosome organization in Drosophila Q Szabo, D Jost, JM Chang, DI Cattoni, GL Papadopoulos, B Bonev, ... Science advances 4 (2), eaar8082, 2018 | 258 | 2018 |
Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation T Sexton, F Bantignies, G Cavalli Seminars in cell & developmental biology 20 (7), 849-855, 2009 | 142 | 2009 |
A chromatin insulator driving three-dimensional Polycomb response element (PRE) contacts and Polycomb association with the chromatin fiber I Comet, B Schuettengruber, T Sexton, G Cavalli Proceedings of the National Academy of Sciences 108 (6), 2294-2299, 2011 | 126 | 2011 |
The role of transcription factories in large-scale structure and dynamics of interphase chromatin T Sexton, D Umlauf, S Kurukuti, P Fraser Seminars in cell & developmental biology 18 (5), 691-697, 2007 | 81 | 2007 |
Cooperativity, specificity, and evolutionary stability of Polycomb targeting in Drosophila B Schuettengruber, NO Elkayam, T Sexton, M Entrevan, S Stern, ... Cell reports 9 (1), 219-233, 2014 | 76 | 2014 |
Defining functionally relevant spatial chromatin domains: it is a TAD complicated N Sikorska, T Sexton Journal of molecular biology 432 (3), 653-664, 2020 | 57 | 2020 |
Sensitive detection of chromatin coassociations using enhanced chromosome conformation capture on chip T Sexton, S Kurukuti, JA Mitchell, D Umlauf, T Nagano, P Fraser Nature protocols 7 (7), 1335-1350, 2012 | 52 | 2012 |
Polycomb: a paradigm for genome organization from one to three dimensions A Delest, T Sexton, G Cavalli Current opinion in cell biology 24 (3), 405-414, 2012 | 49 | 2012 |
Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation T Schauer, Y Ghavi‐Helm, T Sexton, C Albig, C Regnard, G Cavalli, ... EMBO reports 18 (10), 1854-1868, 2017 | 38 | 2017 |
ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C Y Ben Zouari, AM Molitor, N Sikorska, V Pancaldi, T Sexton Genome biology 20, 1-19, 2019 | 28 | 2019 |
Myod1 and GR coordinate myofiber-specific transcriptional enhancers D Rovito, AI Rerra, V Ueberschlag-Pitiot, S Joshi, N Karasu, ... Nucleic acids research 49 (8), 4472-4492, 2021 | 20 | 2021 |
Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains V Ea, T Sexton, T Gostan, L Herviou, MO Baudement, Y Zhang, S Berlivet, ... BMC genomics 16, 1-12, 2015 | 17 | 2015 |
4See: a flexible browser to explore 4C data Y Ben Zouari, A Platania, AM Molitor, T Sexton Frontiers in Genetics 10, 1372, 2020 | 16 | 2020 |
The 3D genome shapes up for pluripotency T Sexton, G Cavalli Cell Stem Cell 13 (1), 3-4, 2013 | 16 | 2013 |
Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus T Taylor, N Sikorska, VM Shchuka, S Chahar, C Ji, NN Macpherson, ... Genes & Development 36 (11-12), 699-717, 2022 | 15 | 2022 |