Markus-Frederik Bohn
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
11412020
Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A
MA Carpenter, M Li, A Rathore, L Lackey, EK Law, AM Land, B Leonard, ...
Journal of Biological Chemistry 287 (41), 34801-34808, 2012
1202012
Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain
MF Bohn, SMD Shandilya, JS Albin, T Kouno, BD Anderson, ...
Structure 21 (6), 1042-1050, 2013
1032013
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity
T Kouno, TV Silvas, BJ Hilbert, SMD Shandilya, MF Bohn, BA Kelch, ...
Nature communications 8 (1), 1-8, 2017
772017
The ssDNA mutator APOBEC3A is regulated by cooperative dimerization
MF Bohn, SMD Shandilya, TV Silvas, EA Nalivaika, T Kouno, BA Kelch, ...
Structure 23 (5), 903-911, 2015
742015
Immunoproteasome functions explained by divergence in cleavage specificity and regulation
MB Winter, F La Greca, S Arastu-Kapur, F Caiazza, P Cimermancic, ...
Elife 6, e27364, 2017
262017
A computational analysis of the structural determinants of APOBEC3’s catalytic activity and vulnerability to HIV-1 Vif
SMD Shandilya, MF Bohn, CA Schiffer
Virology 471, 105-116, 2014
252014
Ehlers–Danlos Syndrome Caused by Biallelic TNXB Variants in Patients with Congenital Adrenal Hyperplasia
W Chen, AF Perritt, R Morissette, JL Dreiling, MF Bohn, A Mallappa, Z Xu, ...
Human mutation 37 (9), 893-897, 2016
192016
A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing. bioRxiv
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, MJ O’Meara, ...
Preprint posted March 22, 2020
162020
Global substrate specificity profiling of post‐translational modifying enzymes
SL Ivry, NO Meyer, MB Winter, MF Bohn, GM Knudsen, AJ O'Donoghue, ...
Protein Science 27 (3), 584-594, 2018
142018
Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization
B Wang, D Asarnow, WH Lee, CW Huang, B Faust, PML Ng, EZX Ngoh, ...
bioRxiv, 2020
122020
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases
M Ravalin, P Theofilas, K Basu, KA Opoku-Nsiah, VA Assimon, ...
Nature chemical biology 15 (8), 786-794, 2019
122019
Structural determination of the broadly reactive anti-IGHV1-69 anti-idiotypic antibody G6 and its idiotope
Y Avnir, KL Prachanronarong, Z Zhang, S Hou, EC Peterson, J Sui, ...
Cell reports 21 (11), 3243-3255, 2017
102017
Allosteric inhibitors, crystallography, and comparative analysis reveal network of coordinated movement across human herpesvirus proteases
TM Acker, JE Gable, MF Bohn, P Jaishankar, MC Thompson, JS Fraser, ...
Journal of the American Chemical Society 139 (34), 11650-11653, 2017
72017
Garc, amp, iacute-Sastre A
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, MJ O'Meara, ...
Jura, M. von Zastrow, J. Taunton, O. Schwartz, M. Vignuzzi, C. Enfert, S …, 2020
62020
REdiii: a pipeline for automated structure solution
MF Bohn, CA Schiffer
Acta Crystallographica Section D: Biological Crystallography 71 (5), 1059-1067, 2015
12015
Structure of an affinity-matured inhibitory recombinant fab against urokinase plasminogen activator reveals basis of potency and specificity
N Sevillano, MF Bohn, M Zimanyi, Y Chen, C Petzold, S Gupta, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1869 (2), 140562, 2020
2020
Die Ehlers-Danlos-Syndrome mit Schwerpunkt auf dem hypermobilen Typ
KU Sturm, MF Bohn
Journal für Mineralstoffwechsel & Muskuloskelettale Erkrankungen 26 (1), 12-22, 2019
2019
Allosteric inhibition via two-step enzyme isomerization of human herpesvirus protease protein-protein interaction decreases viral infectivity of Kaposi's sarcoma-associated …
T Acker, J Gable, M Bohn, P Jaishankar, A Renslo, C Craik
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Structural Comparison of Firefly Luciferase with the Latent Luciferase CG6178
S Adams Jr, M Bohn, C Schiffer, S Miller
The FASEB Journal 29, 573.46, 2015
2015
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