|Leishmaniasis: drugs in the clinic, resistance and new developments|
M Ouellette, J Drummelsmith, B Papadopoulou
Drug Resistance Updates 7 (4-5), 257-266, 2004
|Drug resistance and treatment failure in leishmaniasis: A 21st century challenge|
A Ponte-Sucre, F Gamarro, JC Dujardin, MP Barrett, R López-Vélez, ...
PLoS neglected tropical diseases 11 (12), e0006052, 2017
|Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages|
C Dumas, M Ouellette, J Tovar, ML Cunningham, AH Fairlamb, S Tamar, ...
The EMBO journal 16 (10), 2590-2598, 1997
|Developmental regulation of gene expression in trypanosomatid parasitic protozoa|
S Haile, B Papadopoulou
Current opinion in microbiology 10 (6), 569-577, 2007
|The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase|
D Légaré, D Richard, R Mukhopadhyay, YD Stierhof, BP Rosen, ...
Journal of Biological Chemistry 276 (28), 26301-26307, 2001
|A novel antifolate resistance gene on the amplified H circle of Leishmania.|
B Papadopoulou, G Roy, M Ouellette
The EMBO journal 11 (10), 3601-3608, 1992
|Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages|
S Duclos, R Diez, J Garin, B Papadopoulou, A Descoteaux, H Stenmark, ...
Journal of cell science 113 (19), 3531-3541, 2000
|A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum|
F McNicoll, J Drummelsmith, M Müller, É Madore, N Boilard, M Ouellette, ...
Proteomics 6 (12), 3567-3581, 2006
|A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3′-untranslated region element|
N Boucher, Y Wu, C Dumas, M Dubé, D Sereno, M Breton, ...
Journal of Biological Chemistry 277 (22), 19511-19520, 2002
|Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models|
G Roy, C Dumas, D Sereno, Y Wu, AK Singh, MJ Tremblay, M Ouellette, ...
Molecular and biochemical parasitology 110 (2), 195-206, 2000
|Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy|
JM Ubeda, D Légaré, F Raymond, AA Ouameur, S Boisvert, P Rigault, ...
Genome biology 9 (7), 1-16, 2008
|An ATP-dependent As (III)-glutathione transport system in membrane vesicles of Leishmania tarentolae|
S Dey, M Ouellette, J Lightbody, B Papadopoulou, BP Rosen
Proceedings of the National Academy of Sciences 93 (5), 2192-2197, 1996
|Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species|
A Rochette, F Raymond, JM Ubeda, M Smith, N Messier, S Boisvert, ...
BMC genomics 9 (1), 1-26, 2008
|Mechanisms of drug resistance in Leishmania|
M Ouellette, B Papadopoulou
Parasitology Today 9 (5), 150-153, 1993
|Amplification of the ABC transporter gene PGPA and increased trypanothione levels in potassium antimonyl tartrate (SbIII) resistant Leishmania tarentolae.|
A Haimeur, C Brochu, PA Genest, B Papadopoulou, M Ouellette
Molecular and biochemical parasitology 108 (1), 131-135, 2000
|Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species|
F Raymond, S Boisvert, G Roy, JF Ritt, D Legare, A Isnard, M Stanke, ...
Nucleic acids research 40 (3), 1131-1147, 2012
|Role of the ABC Transporter MRPA (PGPA) in Antimony Resistance in Leishmania infantum Axenic and Intracellular Amastigotes|
K El Fadili, N Messier, P Leprohon, G Roy, C Guimond, N Trudel, ...
Antimicrobial Agents and Chemotherapy 49 (5), 1988-1993, 2005
|Contribution of the Leishmania P-glycoprotein-related gene ltpgpA to oxyanion resistance.|
B Papadopoulou, G Roy, S Dey, BP Rosen, M Ouellette
Journal of Biological Chemistry 269 (16), 11980-11986, 1994
|A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins|
Y Wu, Y El Fakhry, D Sereno, S Tamar, B Papadopoulou
Molecular and biochemical parasitology 110 (2), 345-357, 2000
|A proteomic approach to identify developmentally regulated proteins in Leishmania infantum|
Y El Fakhry, M Ouellette, B Papadopoulou
Proteomics 2 (8), 1007-1017, 2002