CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineering CKL Wang, Q Kaas, L Chiche, DJ Craik Nucleic acids research 36 (suppl_1), D206-D210, 2007 | 312 | 2007 |
Distribution and evolution of circular miniproteins in flowering plants CW Gruber, AG Elliott, DC Ireland, PG Delprete, S Dessein, U Goransson, ... The Plant Cell 20 (9), 2471-2483, 2008 | 299 | 2008 |
ConoServer, a database for conopeptide sequences and structures Q Kaas, JC Westermann, R Halai, CKL Wang, DJ Craik Bioinformatics 24 (3), 445-446, 2008 | 237 | 2008 |
Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedoensis CKL Wang, ML Colgrave, KR Gustafson, DC Ireland, U Goransson, ... Journal of natural products 71 (1), 47-52, 2008 | 207 | 2008 |
Designing macrocyclic disulfide-rich peptides for biotechnological applications CK Wang, DJ Craik Nature chemical biology 14 (5), 417-427, 2018 | 203 | 2018 |
Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity SM Simonsen, L Sando, KJ Rosengren, CK Wang, ML Colgrave, NL Daly, ... Journal of biological chemistry 283 (15), 9805-9813, 2008 | 199 | 2008 |
Cyclotides as natural anti‐HIV agents DC Ireland, CKL Wang, JA Wilson, KR Gustafson, DJ Craik Peptide science 90 (1), 51-60, 2008 | 179 | 2008 |
CyBase: a database of cyclic protein sequence and structure JP Mulvenna, C Wang, DJ Craik Nucleic acids research 34 (suppl_1), D192-D194, 2006 | 178 | 2006 |
The cyclotide family of circular miniproteins: nature's combinatorial peptide template DJ Craik, M Čemažar, CKL Wang, NL Daly Peptide Science: original Research on Biomolecules 84 (3), 250-266, 2006 | 172 | 2006 |
Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients CK Wang, SE Northfield, B Colless, S Chaousis, I Hamernig, RJ Lohman, ... Proceedings of the National Academy of Sciences 111 (49), 17504-17509, 2014 | 155 | 2014 |
Molecular grafting onto a stable framework yields novel cyclic peptides for the treatment of multiple sclerosis CK Wang, CW Gruber, M Cemazar, C Siatskas, P Tagore, N Payne, ... ACS chemical biology 9 (1), 156-163, 2014 | 152 | 2014 |
The anthelmintic activity of the cyclotides: natural variants with enhanced activity ML Colgrave, AC Kotze, DC Ireland, CK Wang, DJ Craik Chembiochem 9 (12), 1939-1945, 2008 | 148 | 2008 |
Disulfide-rich macrocyclic peptides as templates in drug design SE Northfield, CK Wang, CI Schroeder, T Durek, MW Kan, JE Swedberg, ... European Journal of Medicinal Chemistry 77, 248-257, 2014 | 141 | 2014 |
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold CK Wang, SH Hu, JL Martin, T Sjogren, J Hajdu, L Bohlin, P Claeson, ... Journal of Biological Chemistry 284 (16), 10672-10683, 2009 | 129 | 2009 |
Cyclic peptide oral bioavailability: lessons from the past CK Wang, DJ Craik Peptide Science 106 (6), 901-909, 2016 | 118 | 2016 |
Conformational flexibility is a determinant of permeability for cyclosporin CK Wang, JE Swedberg, PJ Harvey, Q Kaas, DJ Craik The Journal of Physical Chemistry B 122 (8), 2261-2276, 2018 | 112 | 2018 |
Extensions of PDZ domains as important structural and functional elements CK Wang, L Pan, J Chen, M Zhang Protein & cell 1, 737-751, 2010 | 101 | 2010 |
Isolation and characterization of cytotoxic cyclotides from Viola tricolor J Tang, CK Wang, X Pan, H Yan, G Zeng, W Xu, W He, NL Daly, DJ Craik, ... Peptides 31 (8), 1434-1440, 2010 | 96 | 2010 |
Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes CK Wang, ML Colgrave, DC Ireland, Q Kaas, DJ Craik Biophysical Journal 97 (5), 1471-1481, 2009 | 95 | 2009 |
Chlorotoxin: Structure, activity, and potential uses in cancer therapy PG Ojeda, CK Wang, DJ Craik Peptide Science 106 (1), 25-36, 2016 | 92 | 2016 |