Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer KA Leinonen, OR Saramäki, B Furusato, T Kimura, H Takahashi, S Egawa, ... Cancer epidemiology, biomarkers & prevention 22 (12), 2333-2344, 2013 | 155 | 2013 |
Association of SPINK1 Expression and TMPRSS2:ERG Fusion with Prognosis in Endocrine-Treated Prostate Cancer KA Leinonen, TT Tolonen, H Bracken, UH Stenman, TLJ Tammela, ... Clinical Cancer Research 16 (10), 2845-2851, 2010 | 134 | 2010 |
Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer A Urbanucci, SJ Barfeld, V Kytölä, HM Itkonen, IM Coleman, D Vodák, ... Cell reports 19 (10), 2045-2059, 2017 | 123 | 2017 |
EZH2, Ki‐67 and MCM7 are prognostic markers in prostatectomy treated patients S Laitinen, PM Martikainen, T Tolonen, J Isola, TLJ Tammela, T Visakorpi International journal of cancer 122 (3), 595-602, 2008 | 118 | 2008 |
ImmunoMembrane: a publicly available web application for digital image analysis of HER2 immunohistochemistry VJ Tuominen, TT Tolonen, J Isola Histopathology 60 (5), 758-767, 2012 | 95 | 2012 |
Dual‐specificity phosphatase 1 and serum/glucocorticoid‐regulated kinase are downregulated in prostate cancer HE Rauhala, KP Porkka, TT Tolonen, PM Martikainen, TLJ Tammela, ... International journal of cancer 117 (5), 738-745, 2005 | 95 | 2005 |
Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections–a randomized controlled trial KE Hietanen, TA Järvinen, H Huhtala, TT Tolonen, HO Kuokkanen, ... Journal of Plastic, Reconstructive & Aesthetic Surgery 72 (1), 4-11, 2019 | 91 | 2019 |
Atorvastatin versus placebo for prostate cancer before radical prostatectomy—a randomized, double-blind, placebo-controlled clinical trial TJ Murtola, H Syvälä, T Tolonen, M Helminen, J Riikonen, J Koskimäki, ... European urology 74 (6), 697-701, 2018 | 65 | 2018 |
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse S Taavitsainen, N Engedal, S Cao, F Handle, A Erickson, S Prekovic, ... Nature communications 12 (1), 5307, 2021 | 62 | 2021 |
Overall and worst Gleason scores are equally good predictors of prostate cancer progression TT Tolonen, PM Kujala, TLJ Tammela, VJ Tuominen, JJ Isola, T Visakorpi BMC urology 11, 1-6, 2011 | 54 | 2011 |
Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy DJ Woodcock, E Riabchenko, S Taavitsainen, M Kankainen, G Gundem, ... Nature communications 11 (1), 5070, 2020 | 51 | 2020 |
Cytokeratin-supervised deep learning for automatic recognition of epithelial cells in breast cancers stained for ER, PR, and Ki-67 M Valkonen, J Isola, O Ylinen, V Muhonen, A Saxlin, T Tolonen, M Nykter, ... IEEE transactions on medical imaging 39 (2), 534-542, 2019 | 50 | 2019 |
Microseminoprotein-beta expression in different stages of prostate cancer L Sjöblom, O Saramäki, M Annala, K Leinonen, J Nättinen, T Tolonen, ... PloS one 11 (3), e0150241, 2016 | 40 | 2016 |
Optimized JPEG 2000 compression for efficient storage of histopathological whole-slide images H Helin, T Tolonen, O Ylinen, P Tolonen, J Napankangas, J Isola Journal of pathology informatics 9 (1), 20, 2018 | 39 | 2018 |
Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer GS Bova, HML Kallio, M Annala, K Kivinummi, G Högnäs, S Häyrynen, ... Molecular Case Studies 2 (3), a000752, 2016 | 33 | 2016 |
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations A Khanna, JK Rane, KK Kivinummi, A Urbanucci, MA Helenius, ... Oncotarget 6 (23), 19661, 2015 | 32 | 2015 |
Histopathological variables and biomarkers enhancer of zeste homologue 2, Ki‐67 and minichromosome maintenance protein 7 as prognosticators in primarily endocrine‐treated … TT Tolonen, TLJ Tammela, PM Kujala, VJ Tuominen, JJ Isola, T Visakorpi BJU international 108 (9), 1430-1438, 2011 | 29 | 2011 |
Expression of the miR-200 family in tumor tissue, plasma and urine of epithelial ovarian cancer patients in comparison to benign counterparts K Savolainen, M Scaravilli, A Ilvesmäki, S Staff, T Tolonen, JU Mäenpää, ... BMC research notes 13, 1-7, 2020 | 27 | 2020 |
Computer-aided breast cancer histopathological diagnosis: Comparative analysis of three DTOCS-based features: SW-DTOCS, SW-WDTOCS and SW-3-4-DTOCS I Pöllänen, B Braithwaite, T Ikonen, H Niska, K Haataja, P Toivanen, ... 2014 4th International Conference on Image Processing Theory, Tools and …, 2014 | 25 | 2014 |
Expression of neuroendocrine differentiation markers in lethal metastatic castration-resistant prostate cancer M Sainio, T Visakorpi, T Tolonen, J Ilvesaro, GS Bova Pathology-Research and Practice 214 (6), 848-856, 2018 | 24 | 2018 |