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Alexander J. Najibi
Alexander J. Najibi
Ph.D. Student, Harvard University
E-mail confirmado em g.harvard.edu - Página inicial
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Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors
H Wang, AJ Najibi, MC Sobral, BR Seo, JY Lee, D Wu, AW Li, ...
Nature communications 11 (1), 5696, 2020
1202020
Matrix viscoelasticity controls spatiotemporal tissue organization
A Elosegui-Artola, A Gupta, AJ Najibi, BR Seo, R Garry, CM Tringides, ...
Nature materials 22 (1), 117-127, 2023
952023
A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia
NJ Shah, AJ Najibi, TY Shih, AS Mao, A Sharda, DT Scadden, DJ Mooney
Nature Biomedical Engineering 4 (1), 40-51, 2020
852020
CD4 T-cells regulate angiogenesis and myogenesis
BJ Kwee, E Budina, AJ Najibi, DJ Mooney
Biomaterials 178, 109-121, 2018
522018
Cell and tissue engineering in lymph nodes for cancer immunotherapy
AJ Najibi, DJ Mooney
Advanced drug delivery reviews 161, 42-62, 2020
502020
Acetalated dextran nanoparticles loaded into an injectable alginate cryogel for combined chemotherapy and cancer vaccination
T Bauleth‐Ramos, TY Shih, MA Shahbazi, AJ Najibi, AS Mao, D Liu, ...
Advanced Functional Materials 29 (35), 1903686, 2019
502019
Treating ischemia via recruitment of antigen-specific T cells
BJ Kwee, BR Seo, AJ Najibi, AW Li, TY Shih, D White, DJ Mooney
Science advances 5 (7), eaav6313, 2019
362019
Active tissue adhesive activates mechanosensors and prevents muscle atrophy
S Nam, BR Seo, AJ Najibi, SL McNamara, DJ Mooney
Nature materials 22 (2), 249-259, 2023
232023
Ultrasound-triggered release reveals optimal timing of CpG-ODN delivery from a cryogel cancer vaccine
TY Shih, AJ Najibi, AL Bartlett, AW Li, DJ Mooney
Biomaterials 279, 121240, 2021
152021
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes
AJ Najibi, TY Shih, DJ Mooney
Biomaterials, 121329, 2022
132022
Scaffold Vaccines for Generating Robust and Tunable Antibody Responses
AJ Najibi, MO Dellacherie, TY Shih, EJ Doherty, DA White, ...
Advanced Functional Materials, 2110905, 2022
102022
Adoptive T cell transfer and host antigen-presenting cell recruitment with cryogel scaffolds promotes long-term protection against solid tumors
K Adu-Berchie, JM Brockman, Y Liu, TW To, DKY Zhang, AJ Najibi, ...
Nature Communications 14 (1), 3546, 2023
72023
Targeting tumor extracellular matrix activates the tumor-draining lymph nodes
AJ Najibi, TY Shih, DKY Zhang, J Lou, MC Sobral, H Wang, ...
Cancer Immunology, Immunotherapy 71 (12), 2957-2968, 2022
72022
Chemotherapy dose shapes the expression of immune-interacting markers on cancer cells
AJ Najibi, K Larkin, Z Feng, N Jeffreys, MT Dacus, Y Rustagi, FS Hodi, ...
Cellular and Molecular Bioengineering 15 (6), 535-551, 2022
32022
Immune‐responsive biodegradable scaffolds for enhancing neutrophil regeneration
MD Kerr, DA McBride, WT Johnson, AK Chumber, AJ Najibi, BR Seo, ...
Bioengineering & Translational Medicine 8 (1), e10309, 2023
22023
Biomaterial-based antigen free vaccine and the use thereof
AJ Najibi, NJ Shah, H Wang, DJ Mooney, DT Scadden
US Patent App. 17/701,270, 2022
12022
Lymph node expansion predicts magnitude of vaccine immune response
AJ Najibi, RS Lane, MC Sobral, BR Freedman, JG Estupinan, ...
bioRxiv, 2022.10. 25.513749, 2022
12022
Enhancing adoptive T cell therapy with synergistic host immune engagement promotes long-term protection against solid tumors
K Adu-Berchie, JM Brockman, Y Liu, DKY Zhang, AJ Najibi, A Stafford, ...
bioRxiv, 2022.09. 10.507437, 2022
12022
Abstract PO085: Cryogel-based cancer vaccine to treat acute myeloid leukemia
AJ Najibi, NJ Shah, TY Shih, AS Mao, A Sharda, DT Scadden, DJ Mooney
Cancer Immunology Research 9 (2_Supplement), PO085-PO085, 2021
12021
Biomaterial Scaffold-Based Vaccines Sustain Robust Immune Responses through the Lymph Nodes
AJ Najibi
Harvard University, 2022
2022
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Artigos 1–20