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Tillie L Hackett
Tillie L Hackett
Professor, Department of Anesthesiology, Pharmacology, Therapeutics, University of British Columbia
Verified email at hli.ubc.ca - Homepage
Title
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Year
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
JM Leung, CX Yang, A Tam, T Shaipanich, TL Hackett, GK Singhera, ...
European Respiratory Journal 55 (5), 2020
9642020
Induction of epithelial–mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-β1
TL Hackett, SM Warner, D Stefanowicz, F Shaheen, DV Pechkovsky, ...
American journal of respiratory and critical care medicine 180 (2), 122-133, 2009
4692009
Lung eQTLs to help reveal the molecular underpinnings of asthma
K Hao, Y Bossé, DC Nickle, PD Paré, DS Postma, M Laviolette, ...
PLoS genetics 8 (11), e1003029, 2012
3682012
The contribution of small airway obstruction to the pathogenesis of chronic obstructive pulmonary disease
JC Hogg, PD Paré, TL Hackett
Physiological reviews 97 (2), 529-552, 2017
3012017
Airway epithelial regulation of pulmonary immune homeostasis and inflammation
TS Hallstrand, TL Hackett, WA Altemeier, G Matute-Bello, PM Hansbro, ...
Clinical immunology 151 (1), 1-15, 2014
2822014
Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution
TL Hackett, GK Singhera, F Shaheen, P Hayden, GR Jackson, RG Hegele, ...
American journal of respiratory cell and molecular biology 45 (5), 1090-1100, 2011
2522011
E-cadherin: gatekeeper of airway mucosa and allergic sensitization
MC Nawijn, TL Hackett, DS Postma, AJM van Oosterhout, IH Heijink
Trends in immunology 32 (6), 248-255, 2011
2522011
Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study
HK Koo, DM Vasilescu, S Booth, A Hsieh, OL Katsamenis, N Fishbane, ...
The Lancet Respiratory Medicine 6 (8), 591-602, 2018
2472018
Epithelial–mesenchymal transition in the pathophysiology of airway remodelling in asthma
TL Hackett
Current opinion in allergy and clinical immunology 12 (1), 53-59, 2012
2362012
The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter
JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ...
Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012
2112012
The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation
S Post, MC Nawijn, TL Hackett, M Baranowska, R Gras, ...
Thorax 67 (6), 488-495, 2012
1972012
Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism
D Marchant, GK Singhera, S Utokaparch, TL Hackett, JH Boyd, Z Luo, X Si, ...
Journal of virology 84 (21), 11359-11373, 2010
1782010
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine
CA Brandsma, M Van den Berge, TL Hackett, G Brusselle, W Timens
The Journal of pathology 250 (5), 624-635, 2020
1772020
Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study
TL Hackett, R Holloway, ST Holgate, JA Warner
Respiratory research 9, 1-14, 2008
1692008
Characterization of side population cells from human airway epithelium
TL Hackett, F Shaheen, A Johnson, S Wadsworth, DV Pechkovsky, ...
Stem cells 26 (10), 2576-2585, 2008
1612008
Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
MS Eapen, PM Hansbro, K McAlinden, RY Kim, C Ward, TL Hackett, ...
Scientific reports 7 (1), 13392, 2017
1582017
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK
JD Campbell, JE McDonough, JE Zeskind, TL Hackett, DV Pechkovsky, ...
Genome medicine 4, 1-16, 2012
1582012
Imaging collagen in scar tissue: developments in second harmonic generation microscopy for biomedical applications
L Mostaço-Guidolin, NL Rosin, TL Hackett
International journal of molecular sciences 18 (8), 1772, 2017
1482017
Airway epithelial barrier function regulates the pathogenesis of allergic asthma
IH Heijink, MC Nawijn, TL Hackett
Clinical & Experimental Allergy 44 (5), 620-630, 2014
1392014
DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children
D Stefanowicz, TL Hackett, FS Garmaroudi, OP Günther, S Neumann, ...
Public Library of Science 7 (9), e44213, 2012
1332012
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