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Alaa A. Shafie
Alaa A. Shafie
Assoc. Prof. of Med. Genetics, College of Applied Medical Sciences, Taif University, Saudi Arabia
E-mail confirmado em tu.edu.sa
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Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation
M Xue, MO Weickert, S Qureshi, NB Kandala, A Anwar, M Waldron, ...
Diabetes 65 (8), 2282-2294, 2016
2112016
Genomic variations in the structural proteins of SARS-CoV-2 and their deleterious impact on pathogenesis: a comparative genomics approach
T Mohammad, A Choudhury, I Habib, P Asrani, Y Mathur, M Umair, ...
Frontiers in cellular and infection microbiology 11, 765039, 2021
582021
Structure‐based investigation of MARK4 inhibitory potential of Naringenin for therapeutic management of cancer and neurodegenerative diseases
S Anwar, S Khan, A Shamsi, F Anjum, A Shafie, A Islam, F Ahmad, ...
Journal of cellular biochemistry 122 (10), 1445-1459, 2021
482021
Myricetin inhibits breast and lung cancer cells proliferation via inhibiting MARK4
S Anwar, S Khan, F Anjum, A Shamsi, P Khan, H Fatima, A Shafie, A Islam, ...
Journal of Cellular Biochemistry 123 (2), 359-374, 2022
332022
MAP/Microtubule affinity regulating kinase 4 inhibitory potential of irisin: A new therapeutic strategy to combat cancer and Alzheimer’s disease
R Waseem, S Anwar, S Khan, A Shamsi, MI Hassan, F Anjum, A Shafie, ...
International journal of molecular sciences 22 (20), 10986, 2021
292021
Identification of phytoconstituents as potent inhibitors of casein kinase-1 alpha using virtual screening and molecular dynamics simulations
A Shafie, S Khan, Zehra, T Mohammad, F Anjum, GM Hasan, DK Yadav, ...
Pharmaceutics 13 (12), 2157, 2021
272021
Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro
A Shafie, M Xue, G Barker, D Zehnder, PJ Thornalley, N Rabbani
Biochemical Journal 473 (22), 4255-4270, 2016
262016
Copy number variation of glyoxalase I
A Shafie, M Xue, PJ Thornalley, N Rabbani
Biochemical Society Transactions 42 (2), 500-503, 2014
232014
Combination of pulsed electric field and ultrasound in the extraction of polyphenols and volatile compounds from grape stems
G Ntourtoglou, F Drosou, T Chatzimitakos, V Athanasiadis, E Bozinou, ...
Applied Sciences 12 (12), 6219, 2022
222022
Implications of tempol in pyruvate dehydrogenase kinase 3 targeted anticancer therapeutics: Computational, spectroscopic, and calorimetric studies
S Anwar, D DasGupta, A Shafie, FA Alhumaydhi, SA Alsagaby, ...
Journal of Molecular Liquids 350, 118581, 2022
202022
Identification of intrinsically disorder regions in non-structural proteins of SARS-CoV-2: New insights into drug and vaccine resistance
F Anjum, T Mohammad, P Asrani, A Shafie, S Singh, DK Yadav, ...
Molecular and Cellular Biochemistry 477 (5), 1607-1619, 2022
172022
Bioactive phytoconstituents as potent inhibitors of casein kinase-2: Dual implications in cancer and COVID-19 therapeutics
F Anjum, MN Sulaimani, A Shafie, T Mohammad, GM Ashraf, AL Bilgrami, ...
RSC advances 12 (13), 7872-7882, 2022
172022
Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
A Shafie, S Khan, S Batra, F Anjum, T Mohammad, S Alam, DK Yadav, ...
Plos one 16 (10), e0258929, 2021
132021
Discovery of natural compounds as potential inhibitors of human carbonic anhydrase II: An integrated virtual screening, docking, and molecular dynamics simulation study
F Anjum, F Ali, T Mohammad, A Shafie, O Akhtar, B Abdullaev, I Hassan
OMICS: A Journal of Integrative Biology 25 (8), 513-524, 2021
132021
Impact of single amino acid substitution on the structure and function of TANK‐binding kinase‐1
M Umair, S Khan, T Mohammad, A Shafie, F Anjum, A Islam, MI Hassan
Journal of cellular biochemistry 122 (10), 1475-1490, 2021
122021
Targeting inhibition of microtubule affinity regulating kinase 4 by Harmaline: Strategy to combat Alzheimer's disease
M Adnan, S Anwar, D DasGupta, M Patel, AM Elasbali, HH Alhassan, ...
International Journal of Biological Macromolecules 224, 188-195, 2023
102023
Prevalence of anemia among Saudi patients with solid cancers at diagnosis in King Faisal Hospital, Taif Province, Kingdom of Saudi Arabia
M Almehmadi, M Salih, TE Elmissbah, A Alsharif, N Alsiwiehri, ...
PLoS One 16 (1), e0246202, 2021
102021
High-resolution MD simulation studies to get mechanistic insights into the urea-induced denaturation of human sphingosine kinase 1
FI Khan, S Ali, W Chen, F Anjum, A Shafie, MI Hassan, D Lai
Current Topics in Medicinal Chemistry 21 (31), 2839-2850, 2021
92021
Comparative analysis of web-based programs for single amino acid substitutions in proteins
A Choudhury, T Mohammad, F Anjum, A Shafie, IK Singh, B Abdullaev, ...
PloS one 17 (5), e0267084, 2022
82022
Effect of pH on the structure and function of cyclin-dependent kinase 6
M Yousuf, A Shamsi, F Anjum, A Shafie, A Islam, QMR Haque, ...
Plos one 17 (2), e0263693, 2022
82022
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